鼻咽癌发病与二十四节气相关性研究
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摘要
目的:探讨鼻咽癌发病与二十四节气的相关性。方法:收集2013年1月1日至2018年1月1日诊治的194例新发鼻咽癌病例,调查其发病日期,确定其发病节气,采用频数分布和圆形分布统计方法,探讨鼻咽癌发病与二十四节气的相关性。结果:194例鼻咽癌在二十四节气均可发病,未显现特定的发病高峰节气,相对高发的散在节气包括雨水7. 22%(14例)、大暑6. 19%(12例)、小暑5. 67%(11例)、处暑5. 15%(10例)、立春5. 15%(10例)和立冬5. 15%(10例),相对高发的节气区间为芒种至白露。结论:鼻咽癌发病可能与节气相关,芒种至白露为鼻咽癌相对高发节气区间。
Objective: To explore the correlation between the incidence of nasopharyngeal carcinoma and 24 solar terms. Methods:194 cases of nasopharyngeal carcinoma( NPC) diagnosed and treated from January 1,2013 to January 1,2018 were collected. The onset date of NPC was investigated,and the onset season was determined. The correlation between NPC incidence and 24 solar terms was discussed by using frequency distribution and circular distribution statistical methods. Results: 194 cases of nasopharyngeal carcinoma could develop on the 24 th solar terms,and there was no specific peak incidence of solar terms. Relatively high incidence of diffuse solar terms included Yushui 7. 22%( 14 cases),Dashu 6. 19%( 12 cases),Xiaoshu 5. 67%( 11 cases),Chushu5. 15%( 10 cases),Lichun 5. 15%( 10 cases) and Lidong 5. 15%( 10 cases). Relatively high incidence of solar terms ranged from Mangzhong to Bailu. Conclusion: The incidence of nasopharyngeal carcinoma may be related to solar terms. The relative high incidence of nasopharyngeal carcinoma is from Mangzhong to Bailu.
Objective: To explore the correlation between the incidence of nasopharyngeal carcinoma and 24 solar terms. Methods:194 cases of nasopharyngeal carcinoma( NPC) diagnosed and treated from January 1,2013 to January 1,2018 were collected. The onset date of NPC was investigated,and the onset season was determined. The correlation between NPC incidence and 24 solar terms was discussed by using frequency distribution and circular distribution statistical methods. Results: 194 cases of nasopharyngeal carcinoma could develop on the 24 th solar terms,and there was no specific peak incidence of solar terms. Relatively high incidence of diffuse solar terms included Yushui 7. 22%( 14 cases),Dashu 6. 19%( 12 cases),Xiaoshu 5. 67%( 11 cases),Chushu5. 15%( 10 cases),Lichun 5. 15%( 10 cases) and Lidong 5. 15%( 10 cases). Relatively high incidence of solar terms ranged from Mangzhong to Bailu. Conclusion: The incidence of nasopharyngeal carcinoma may be related to solar terms. The relative high incidence of nasopharyngeal carcinoma is from Mangzhong to Bailu.
引文
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[2]田道法,肖调立,何迎春.鼻咽癌的中医药防治[J].中国中西医结合耳鼻咽喉科杂志,2013,21(1):69-74.
[3]梁玲,陈静,梁波,等.中医时间医学研究进展[J].云南中医中药杂志,2007,28(4):46-47.
[4]印会河.中医基础理论[M].上海:上海科学技术出版社,1984:7.
[5]怀超玺.浅谈中国古代历法之二十四节气[J].中国新技术新产品,2009(9):254-255.
[6]彭涛,沈敏鹤,阮善明.浅谈中医时间医学观对肿瘤诊治的指导意义[J].中医杂志,2014,55(4):358-360.
[7]李福俊.新编万年历[M].郑州:中州古籍出版社,1996:4-5.
[8]熊晓芳,钟锡新.慢性胃炎与季节、节气相关性研究[J].新中医,2013,45(11):34-35.
[9]段秀姣. 447例心肌梗塞发病高峰与季节、节气的关系分析[J].中国公共卫生,1997,13(4):18.
[10]彭子益.圆运动古中医学[M].北京:中国中医药出版社,2009:6.
[11]陈实功.徐评外科正宗校注[M].北京:学苑出版社,1997:482-483.
[12]吴谦等.医宗金鉴[M]. 2版.北京:人民卫生出版社,1985:1701-1703.
[13]邹岳.外科真诠[M].长沙:科学技术出版社,1997:1604.
[14]张红,陈孟溪,梁益辉.鼻咽癌初诊患者中医主症、证型规律初步研究[J].中国中医急症,2011,20(12):1925-1927.
[15]王贤文,田道法.初诊鼻咽癌患者临床证型及体质类型调查[J].中国中西医结合耳鼻咽喉科杂志,2007,15(2):116-119.
[16]刘蓬.王德鉴教授学术思想介绍[J].新中医,2004,36(8):5-6.
[17]刘书静,田道法,何迎春,等.鼻咽癌患者初诊中医证型与病灶颅内侵犯潜力的相关性[J].中国中西医结合杂志,2006,26(12):1086-1089.
[18]胡长坤.应用圆形分布法分析鼻咽部恶性肿瘤收治时间的分布规律[J].中国医院统计,1996,3(3):136-138.
[19]周小军,田道法.鼻咽癌古文献研究[J].中华医史杂志,2001,31(2):115-118.
[20]巢元方.诸病源候论[M].北京:中国医药科技出版社,2011:8.
[21]孙思邈.备急千金要方[M].北京:人民卫生出版社,1982:407.
[22]欧杰,李永刚,王兴华.结直肠癌住院患者死亡时间节律初探[J].山东中医药大学学报,2015,39(1):50-52.