全面护理在老年慢性阻塞性肺气肿布地奈德联合硫酸特布他林雾化吸入治疗中的应用效果
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摘要
目的探讨布地奈德联合硫酸特布他林雾化吸入治疗老年慢性阻塞性肺气肿护理效果。方法选取2017年7~12月我院收治的老年慢性阻塞性肺气肿患者50例,根据治疗方法将其分为对照组、观察组,每组25例。所有患者给予布地奈德联合硫酸特布他林雾化吸入治疗,对照组给予普通护理,观察组则给予全面化护理。比较两组老年慢性阻塞性肺气肿临床疗效;平均住院时间、慢性阻塞性肺气肿病因知晓度、用药知识知晓度、遵医行为评分;治疗前后患者肺功能指标(FEV1、FVC以及FEV1/FVC);药物不良反应率。结果观察组患者的临床疗效高于对照组,差异有统计学意义(P<0.05)。治疗前,两组患者肺功能指标(FEV1、FVC以及FEV1/FVC)的比较,差异无统计学意义(P>0.05);两组治疗后的肺功能指标(FEV1、FVC以及FEV1/FVC)均显著优于治疗前,差异有统计学意义(P<0.05)。治疗后观察组肺功能指标(FEV1、FVC以及FEV1/FVC)优于对照组,差异有统计学意义(P<0.05)。观察组患者的平均住院时间短于对照组,慢性阻塞性肺气肿病因知晓度、用药知识知晓度、遵医行为评分高于对照组,差异有统计学意义(P<0.05)。观察组患者的不良反应发生率低于对照组,差异有统计学意义(P<0.05)。结论布地奈德联合硫酸特布他林雾化吸入治疗老年慢性阻塞性肺气肿效果确切,辅以全面护理,可提高患者疾病、用药认知和遵医行为,有效控制病情,缓解不良情绪,改善肺功能和生活质量,减少用药不良事件,值得推广应用。
Objective To investigate the effect of Budesonide combined with Terbutaline Sulfate inhalation therapy for elderly patients with chronic obstructive pulmonary disease.Methods Fifty elderly patients with chronic obstructive pulmonary disease were selected from July to December 2017.According to the treatment methods,they were divided into control group and observation group,25 cases in each group.All patients were given Budesonide combined with Terbutaline Sulfate Aerosol inhalation therapy,the control group was given ordinary care,the observation group was given comprehensive care.The clinical efficacy of COPD in two groups was compared. Average hospital stay,awareness of COPD etiology,knowledge of medication,compliance behavior score were compared.The pulmonary function indexes FEV1,FVC and FEV1/FVC of patients before and after treatment were compared.Adverse drug reaction rate was also compared.Results The clinical efficacy of the observation group was higher than that of the control group,the difference was statistically significant(P<0.05).Before treatment,there was no significant difference in pulmonary function between the two groups(P>0.05).The pulmonary function indexes of FEV1,FVC and FEV1/FVC of the two groups after treatment were significantly better than those before treatment(P<0.05).After treatment,the pulmonary function indexes of FEV1,FVC and FEV1/FVC in the observation group were better than those in the control group,the differences were statistically significant(P<0.05).The average length of hospital stay in the observation group was shorter than that in the control group,the awareness of COPD etiology,knowledge of medication and compliance behavior were higher in the observation group than in the control group(P<0.05).The incidence of adverse reactions in the observation group was lower than those in the control group,the difference was statistically significant(P<0.05).Conclusion The inhalation of Budesonide and Terbutaline Sulfate for the treatment of COPD in the elderly is effective.Supplemented by comprehensive care,it can improve the patient′ s disease,medication awareness and compliance behavior,effectively control the condition,relieve bad mood and improve lung Functional and quality of life,reducing adverse drug events,it is worth promoting.
Objective To investigate the effect of Budesonide combined with Terbutaline Sulfate inhalation therapy for elderly patients with chronic obstructive pulmonary disease.Methods Fifty elderly patients with chronic obstructive pulmonary disease were selected from July to December 2017.According to the treatment methods,they were divided into control group and observation group,25 cases in each group.All patients were given Budesonide combined with Terbutaline Sulfate Aerosol inhalation therapy,the control group was given ordinary care,the observation group was given comprehensive care.The clinical efficacy of COPD in two groups was compared. Average hospital stay,awareness of COPD etiology,knowledge of medication,compliance behavior score were compared.The pulmonary function indexes FEV1,FVC and FEV1/FVC of patients before and after treatment were compared.Adverse drug reaction rate was also compared.Results The clinical efficacy of the observation group was higher than that of the control group,the difference was statistically significant(P<0.05).Before treatment,there was no significant difference in pulmonary function between the two groups(P>0.05).The pulmonary function indexes of FEV1,FVC and FEV1/FVC of the two groups after treatment were significantly better than those before treatment(P<0.05).After treatment,the pulmonary function indexes of FEV1,FVC and FEV1/FVC in the observation group were better than those in the control group,the differences were statistically significant(P<0.05).The average length of hospital stay in the observation group was shorter than that in the control group,the awareness of COPD etiology,knowledge of medication and compliance behavior were higher in the observation group than in the control group(P<0.05).The incidence of adverse reactions in the observation group was lower than those in the control group,the difference was statistically significant(P<0.05).Conclusion The inhalation of Budesonide and Terbutaline Sulfate for the treatment of COPD in the elderly is effective.Supplemented by comprehensive care,it can improve the patient′ s disease,medication awareness and compliance behavior,effectively control the condition,relieve bad mood and improve lung Functional and quality of life,reducing adverse drug events,it is worth promoting.
引文
[1]陈婧.硫酸特布他林雾化吸入致患儿血糖升高[J].药物不良反应杂志,2017,19(2):134-135.
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[8]范存斌.老年慢性阻塞性肺气肿患者治疗中布地奈德及特布他林联合氨茶碱的临床疗效[J].当代医学,2017,23(27):110-111.
[9]华盼金.布地奈德联合特布他林雾化治疗术后咳嗽疗效观察[J].当代医学,2018,24(2):65-67.
[10]杨玉博.尤瑞克林对急性脑梗死疗效观察及对CPR的影响[J].现代诊断与治疗,2017,28(6):1108-1109.
[11]梁水仙.布地奈德与特布他林气动雾化吸入对小儿毛细支气管炎患者的疗效及其护理对策[J].抗感染药学,2017,14(6):1245-1248.
[12]罗政,皮红英.国内6种核心期刊近5年慢性阻塞性肺疾病患者护理的文献定量分析[J].解放军护理杂志,2017,34(18):31-34,37.
[13]李启芬.社区康复护理对老年慢性阻塞性肺气肿患者生活质量的影响[J].齐鲁护理杂志,2011,17(24):85.
[14]邵凤珍.特布他林、布地奈德治疗小儿喘憋性肺炎的全程系统护理及效果[J].实用临床医学,2017,18(4):98-99.
[15]房春花,梁丽华,罗育琴,等.布地奈德、特布他林及异丙托溴胺三联雾化吸入治疗COPD患者的疗效及护理[J].中国医药科学,2017,7(9):84-87.
[2]Zhao Y,Castiglioni S,Fent K.Synthetic progestins medroxyprogesterone acetate and dydrogesterone and their binary mixtures adversely affect reproduction and lead to histological and transcriptional alterations in zebrafish(danio rerio)[J].Environ Sci Technol,2015,49(7):4636-4645.
[3]邱玉明,李剑雄.布地奈德、特布他林、异丙托溴铵联合雾化吸入辅助治疗小儿肺炎链球菌肺炎的临床分析[J].齐齐哈尔医学院学报,2017,38(3):302-303.
[4]El Behery MM,Saleh HS,Ibrahiem MA,et al.Levonorgestrelreleasing intrauterine device versus Dydrogesterone for management of endometrial hyperplasia without atypia[J].Reprod Sci,2015,22(3):329-334.
[5]车向郁.异丙托溴铵联合布地奈德、特布他林雾化吸入对支气管肺炎患儿细胞因子的影响[J].海南医学院学报,2016,22(17):1989-1991,1995.
[6]卢国煊.异丙托溴铵与布地奈德加特布他林雾化吸入在儿童中重度支气管哮喘急性发作治疗中的应用[J].吉林医学,2017,38(2):354-355.
[7]刘振宽,张宇.无创机械通气联合雾化吸入药物治疗AECOPD并发呼吸衰竭的临床观察[J].中国药房,2016,27(20):2833-2835.
[8]范存斌.老年慢性阻塞性肺气肿患者治疗中布地奈德及特布他林联合氨茶碱的临床疗效[J].当代医学,2017,23(27):110-111.
[9]华盼金.布地奈德联合特布他林雾化治疗术后咳嗽疗效观察[J].当代医学,2018,24(2):65-67.
[10]杨玉博.尤瑞克林对急性脑梗死疗效观察及对CPR的影响[J].现代诊断与治疗,2017,28(6):1108-1109.
[11]梁水仙.布地奈德与特布他林气动雾化吸入对小儿毛细支气管炎患者的疗效及其护理对策[J].抗感染药学,2017,14(6):1245-1248.
[12]罗政,皮红英.国内6种核心期刊近5年慢性阻塞性肺疾病患者护理的文献定量分析[J].解放军护理杂志,2017,34(18):31-34,37.
[13]李启芬.社区康复护理对老年慢性阻塞性肺气肿患者生活质量的影响[J].齐鲁护理杂志,2011,17(24):85.
[14]邵凤珍.特布他林、布地奈德治疗小儿喘憋性肺炎的全程系统护理及效果[J].实用临床医学,2017,18(4):98-99.
[15]房春花,梁丽华,罗育琴,等.布地奈德、特布他林及异丙托溴胺三联雾化吸入治疗COPD患者的疗效及护理[J].中国医药科学,2017,7(9):84-87.