世居高原藏族高血压患者高尿酸血症发病率相关因素分析
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摘要
目的:探讨世居高原藏族高血压患者高尿酸血症发病率相关因素。方法:收治藏族高血压患者613例,按是否合并高尿酸血症分为A组346例和B组267例,收集两组患者的体重指数(BMI)、血压、血脂、血糖等指标,经多因素Logistic回归分析合并高尿酸血症的危险因素。结果:BMI、空腹血糖(FBG)、甘油三酯(TG)、总胆固醇(TC)、低密度脂蛋白(LDL-C)均为世居高原藏族高血压患者合并高尿酸血症的危险因素(P<0.05)。结论:世居高原藏族高血压患者易发生高尿酸血症,其发生的风险因素亦较多,临床需重视高原藏族人群高尿酸血症的防治。
Objective:To explore the correlative factors of hyperuricemia in Tibetan hypertension patients living in Plateau.Methods:613 Tibetan hypertensive patients were selected,they were divided into the group A(346 cases)and the group B(267 cases)according to whether they had hyperuricemia or not.The body mass index(BMI),blood pressure,blood lipid,blood sugar and other indicators of the two groups were collected,and the risk factors of hyperuricemia were analyzed by multivariate logistic regression.Results:BMI,fasting blood glucose(FBG),triglyceride(TG),total cholesterol(TC),low density lipoprotein(LDL-C)were all risk factors for hyperuricemia in Tibetan hypertension patients living at high altitude(P<0.05).Conclusion:Hyperuricemia is easy to occur in Tibetan hypertensive patients at high altitude,and there are many risk factors.Clinically,attention should be paid to the prevention and treatment of hyperuricemia in Tibetan population at high altitude.
Objective:To explore the correlative factors of hyperuricemia in Tibetan hypertension patients living in Plateau.Methods:613 Tibetan hypertensive patients were selected,they were divided into the group A(346 cases)and the group B(267 cases)according to whether they had hyperuricemia or not.The body mass index(BMI),blood pressure,blood lipid,blood sugar and other indicators of the two groups were collected,and the risk factors of hyperuricemia were analyzed by multivariate logistic regression.Results:BMI,fasting blood glucose(FBG),triglyceride(TG),total cholesterol(TC),low density lipoprotein(LDL-C)were all risk factors for hyperuricemia in Tibetan hypertension patients living at high altitude(P<0.05).Conclusion:Hyperuricemia is easy to occur in Tibetan hypertensive patients at high altitude,and there are many risk factors.Clinically,attention should be paid to the prevention and treatment of hyperuricemia in Tibetan population at high altitude.
引文
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[3]国家基本公共卫生服务项目基层高血压管理办公室,基层高血压管理专家委员会.国家基层高血压防治管理指南[J].中国循环杂志,2017,32(11):1041-1048.
[4]中华医学会内分泌学分会.高尿酸血症和痛风治疗的中国专家共识[J].中华内分泌代谢杂志,2013,29(11):913-920.
[5] Kim SY,Guevara JP,Kim KM,et al.Hyperuricemia and coronary heart disease:a systematic review and meta analysis[J].Arthritis Care&Research,2010,62(2):170-180.
[6] Borghi C,Cosentino ER,Rinaldi ER,et al.Uricaemia and ejection fraction in elderly heart failure outpatients[J].European Journal of Clinical Investigation,2014,44(6):573-577.
[7]方迎昕.高尿酸血症[J].中国实用乡村医生杂志,2018,25(2):9-10.
[8]贺斌,李小萍,魏玲,等.高原地区高血压患者血尿酸水平的研究[J].实用医院临床杂志,2011,8(3):34-35.
[9]杨丽辉,宋嘉,石荔,等.拉萨市区成年人高尿酸血症和痛风的流行病学调查[J].西部医学,2015,27(10):1476-1478.
[10]陶世冰,任艳,冉兴无,等.四川地区成年人高尿酸血症患病率及相关危险因素的调查性研究[J].四川医学,2018,39(2):133-137.
[11]马娜.原发性老年高血压患者高尿酸血症发病率相关因素分析[J].中国老年保健医学,2018,16(2):38-39.
[2]万强,高艳霞,吴燕升,等.高尿酸血症与心血管疾病关系的研究进展[J].中西医结合心脑血管病杂志,2018,16(1):54-56.
[3]国家基本公共卫生服务项目基层高血压管理办公室,基层高血压管理专家委员会.国家基层高血压防治管理指南[J].中国循环杂志,2017,32(11):1041-1048.
[4]中华医学会内分泌学分会.高尿酸血症和痛风治疗的中国专家共识[J].中华内分泌代谢杂志,2013,29(11):913-920.
[5] Kim SY,Guevara JP,Kim KM,et al.Hyperuricemia and coronary heart disease:a systematic review and meta analysis[J].Arthritis Care&Research,2010,62(2):170-180.
[6] Borghi C,Cosentino ER,Rinaldi ER,et al.Uricaemia and ejection fraction in elderly heart failure outpatients[J].European Journal of Clinical Investigation,2014,44(6):573-577.
[7]方迎昕.高尿酸血症[J].中国实用乡村医生杂志,2018,25(2):9-10.
[8]贺斌,李小萍,魏玲,等.高原地区高血压患者血尿酸水平的研究[J].实用医院临床杂志,2011,8(3):34-35.
[9]杨丽辉,宋嘉,石荔,等.拉萨市区成年人高尿酸血症和痛风的流行病学调查[J].西部医学,2015,27(10):1476-1478.
[10]陶世冰,任艳,冉兴无,等.四川地区成年人高尿酸血症患病率及相关危险因素的调查性研究[J].四川医学,2018,39(2):133-137.
[11]马娜.原发性老年高血压患者高尿酸血症发病率相关因素分析[J].中国老年保健医学,2018,16(2):38-39.