联用葛花醒酒汤和纳洛酮治疗重症急性酒精中毒的效果研讨
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摘要
目的:探讨联用葛花醒酒汤和纳洛酮治疗重症急性酒精中毒的临床效果。方法:选择2016年5月至2018年2月期间什邡市人民医院急诊科收治的100例重症急性酒精中毒患者作为研究对象。将这100例患者分为对照组和观察组,每组各有50例患者。为对照组患者使用纳洛酮进行治疗,为观察组患者联用纳洛酮和葛花醒酒汤进行治疗。然后,比较两组患者治疗后症状消失的时间、意识清醒的时间、出院的时间、用药不良反应的发生率及其对治疗服务的满意率。结果:治疗后,与对照组患者相比,观察组患者症状消失所用的时间、意识清醒所用的时间、及出院的时间均更短,其对治疗服务的满意率更高(P <0.05)。与对照组患者相比,观察组患者用药不良反应的发生率更低(P>0.05)。结论:联用葛花醒酒汤和纳洛酮治疗重症急性酒精中毒的临床效果较好,可使其较快地恢复意识,且安全性较高。
objective: to investigate the clinical effect of gehua-xingjiu decoction combined with naloxone in the treatment of severe acute alcoholism. Methods: 100 patients with severe acute alcoholism admitted to the emergency department of shifang people's hospital from May 2016 to February 2018 were selected as the study subjects. The 100 patients were divided into control group and observation group, with 50 patients in each group. Patients in the control group were treated with naloxone, while patients in the observation group were treated with naloxone and gehua decanting decoction. Then, the time of symptom disappearance, time of consciousness, time of discharge, incidence of adverse drug reactions and satisfaction rate of treatment services were compared between the two groups. Results: after treatment, compared with patients in the control group, patients in the observation group spent less time in symptom disappearance, consciousness, and discharge, with a higher satisfaction rate for treatment services(P < 0.05). Compared with the control group, the incidence of adverse drug reactions was lower in the observation group(P > 0.05). Conclusion: the combination of gehua decoction and naloxone in the treatment of severe acute alcoholism has better clinical effect, can make it recover consciousnessquickly, and has higher safety.
objective: to investigate the clinical effect of gehua-xingjiu decoction combined with naloxone in the treatment of severe acute alcoholism. Methods: 100 patients with severe acute alcoholism admitted to the emergency department of shifang people's hospital from May 2016 to February 2018 were selected as the study subjects. The 100 patients were divided into control group and observation group, with 50 patients in each group. Patients in the control group were treated with naloxone, while patients in the observation group were treated with naloxone and gehua decanting decoction. Then, the time of symptom disappearance, time of consciousness, time of discharge, incidence of adverse drug reactions and satisfaction rate of treatment services were compared between the two groups. Results: after treatment, compared with patients in the control group, patients in the observation group spent less time in symptom disappearance, consciousness, and discharge, with a higher satisfaction rate for treatment services(P < 0.05). Compared with the control group, the incidence of adverse drug reactions was lower in the observation group(P > 0.05). Conclusion: the combination of gehua decoction and naloxone in the treatment of severe acute alcoholism has better clinical effect, can make it recover consciousnessquickly, and has higher safety.
引文
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[15]郑继昌.加味葛花解酲汤联合纳洛酮治疗重症急性酒精中毒疗效观察[J].养生保健指南,2017,12(30):264-264.
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[3]程益锋,卢阳,范笙艳,等.参麦注射液联合布地奈德治疗急性酒精中毒合并吸入性肺炎的临床研究[J].中国现代医学杂志,2015,25(7):100-103.
[4]司贤峰.急性酒精中毒合并脑出血的应急治疗[J].中国实用神经疾病杂志,2016,19(23):104-105.
[5]黄宁利,巩红霞,党红絮,等.急性酒精中毒的促醒治疗和护理要点分析[J].中国中医急症,2015,24(10):1878-1880.
[6]张剑.急性酒精中毒内科急诊治疗疗效研究[J].中国医药科学,2015,5(11):199-201,204.
[7]高万露,汪小海.急性酒精中毒药物治疗新进展[J].药学与临床研究,2015,23(1):59-61.
[8]段茜.急性酒精中毒387例诊治体会[J].临床合理用药杂志,2015,8(2):163-163,164.
[9]罗骞,涂星,熊芬等.醒脑静注射液联合纳洛酮治疗急性酒精中毒的经济学分析[J].西北药学杂志,2015,8(6):747-750.
[10]曾迎胜.醒脑静治疗急性酒精中毒50例[J].中国药业,2016,25(2):120-121,122.
[11]周红勤.纳洛酮治疗急性酒精中毒的效果观察与护理配合[J].包头医学院学报,2015,31(11):57-58.
[12]李敏,白伟娜.大剂量纳洛酮联合醒脑静治疗重度急性酒精中毒效果观察[J].临床合理用药杂志,2016,9(16):29-30.
[13]林柳廷.葛花解醒汤对急性酒精中毒患者的疗效评价[J].大家健康(下旬版),2016,10(10):43-43.
[14]高秀霞,朱立恩,王俊平,等.加味葛花解酲汤联合纳洛酮治疗重症急性酒精中毒疗效观察[J].现代中西医结合杂志,2017,26(21):2328-2330.
[15]郑继昌.加味葛花解酲汤联合纳洛酮治疗重症急性酒精中毒疗效观察[J].养生保健指南,2017,12(30):264-264.