新型全光纤交叉偏振光学相干层析成像系统
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摘要
交叉偏振图像不但可以反映样品的偏振敏感结构信息,而且可以更好地反映出样品浅表层的微结构。因此利用光学相干层析成像技术(OCT)获取样品的交叉偏振图像越来越受到人们的关注。在前人的基础上,实现了一种基于单模光纤的新型全光纤交叉偏振光学相干层析成像系统(CP-OCT),该系统具有同时获得样品的交叉偏振信号和同向偏振信号的功能。详细介绍了CP-OCT系统信号的形成原理,并使用琼斯矩阵理论推导出交叉偏振信号和同向偏振信号的表达式。使用CP-OCT系统分别对玻璃片、中心波长为1310nm的λ/4波片及在体皮肤进行成像,从实验上验证了全光纤CP-OCT系统具有同时获取样品偏振敏感结构与偏振不敏感结构信息的能力。
Cross-polarized image can provide both polarization-sensitive information and a more clear sub-surface structure of the sample.As a result,getting the cross-polarized image by using optical coherence tomography(OCT) becomes more and more popular.A novel fiber-based cross-polarized optical coherence tomography(CP-OCT) system is implemented,which is capable of acquiring both cross-polarized signal and co-polarized signal of a sample simultaneously.Forming principles of both cross-polarized and co-polarized signals are described,and the expressions of them are derived using Jones matrix.The images of a glass slide,a λ/4 wave plate at a wavelength of 1310 nm,and vivo skin obtained with the system confirm that CP-OCT can provide both polarization-sensitive and polarization-insensitive informations of the sample.
Cross-polarized image can provide both polarization-sensitive information and a more clear sub-surface structure of the sample.As a result,getting the cross-polarized image by using optical coherence tomography(OCT) becomes more and more popular.A novel fiber-based cross-polarized optical coherence tomography(CP-OCT) system is implemented,which is capable of acquiring both cross-polarized signal and co-polarized signal of a sample simultaneously.Forming principles of both cross-polarized and co-polarized signals are described,and the expressions of them are derived using Jones matrix.The images of a glass slide,a λ/4 wave plate at a wavelength of 1310 nm,and vivo skin obtained with the system confirm that CP-OCT can provide both polarization-sensitive and polarization-insensitive informations of the sample.
引文
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20V.M.Gelikonov,G.V.Gelikonov.New approach to cross-polarized optical coherence tomography based on orthogonal arbitrarilypolarized modes[J].Laser Physics Letters,2006,3(9):445～451
21Meng Zhuo,X.Steve Yao,Lan Shoufeng et al..Study ofautomatic elimination of polarization fluctuation method for all-fiber oral OCT system[J].Journal of Optoelectronics.Laser,2009,20(1):133～136孟卓,姚晓天,兰寿锋等.全光纤口腔OCT系统偏振波动自动消除方法研究[J].光电子.激光,2009,20(1):133～136
22Li Chen,Zhang Chunxi,Liang Sheng et al..Analysis ofpolarization dependence of fiber optic security systems[J].Journal of Beijing University of Aeronautics and Astronautics,2010,36(9):1099～1102李琛,张春熹,梁生等.干涉型光纤安防系统偏振误差机理分析[J].北京航空航天大学学报,2010,36(9):1099～1102
23M.C.Pierce,R.L.Sheridan,B.H.Park et al..Collagendenaturation can be quantified in burned human skin usingpolarization-sensitive optical coherence tomography[J].Burns,2004,30(6):511～517
2Huang Bingjie,Bu Peng,Wang Xiangzhao et al..Opticalcoherence tomography based on depth resolved dispersioncompensation[J].Acta Optica Sinica,2012,32(2):0217002黄炳杰,步鹏,王向朝等.用于频域光学相干层析成像的深度分辨色散补偿方法[J].光学学报,2012,32(2):0217002
3Yang Liu,Wang Chuan,Ding Zhihua et al..Image reconstruction indioptric media for spectral domain optical coherence tomography[J].Chinese J.Lasers,2011,38(5):0504001杨柳,王川,丁志华等.屈光介质中谱域光学相干层析成像的重构[J].中国激光,2011,38(5):0504001
4Yang Lifeng,Zeng Nan,Chen Dongsheng.Characterization ofdehydration and proteolysis process of chicken muscle usingpolarization-sensitive optical coherence tomography[J].ChineseJ.Lasers,2011,38(12):1204002阳利锋,曾楠,陈东胜.偏振敏感光学相干层析对鸡肉组织两种变质过程的表征[J].中国激光,2011,38(12):1204002
5M.R.Hee,D.Huang,E.A.Swansonet al..Polarization-sensitivelow-coherence reflectometer for birefringence characterization andranging[J].J.Opt.Soc.Am.B,1992,9(6):903～908
6Shuliang Jiao,Wurong Yu,George Stoica et al..Optical-fiber-based Muller optical coherence tomography[J].Opt.Lett.,2003,28(14):1206～1208
7B.H.Park.Fiber-Based Polarization-Sensitive Optical CoherenceYomography[D].Irvine:University of California,2005.56～110
8S.Makita,M.Yamanari,Y.Yasuno.Generalized Jones matrixoptical coherence tomography:performance and localbirefringence imaging[J].Opt.Express,2010,18(2):854～876
9Nan Nan,Bu Peng,Guo Xin et al..Three-dimensional full-rangecomplex fourier domain optical coherence tomography system for vivoimaging of human skin[J].Chinese J.Lasers,2012,39(7):0704002南楠,步鹏,郭昕等.三维全深度复频域光学相干层析成像系统及其对人体皮肤的在体成像[J].中国激光,2012,39(7):0704002
10T.Torzicky,M.Pircher,S.Zotter et al..Automatedmeasurement of choroidal thickness in the human eye bypolarization sensitive optical coherence tomography[J].Opt.Express,2012,20(7):7564～7574
11B.Elmaanaoui,B.Wang,J.C.Dwelle et al..Birefringencemeasurement of the retinal nerve fiber layer by swept sourcepolarization sensitive optical coherence tomography[J].Opt.Express,2011,19(11):10252～10268
12C.Rashidifard,S.Martin,N.Kumar et al..Assessment ofrotator cuff tendon integrity with single detector polarizationsensitive optical coherence tomography[C].Lasers and Electro-Optics,2011.ATuC2
13B.J.Vakoc,D.Fukumura,R.K.Jain et al..Cancer imagingby optical coherence tomography:preclinical progress and clinicalpotential[J].Nature Reviews,2012,12:363～368
14B.H.Park,C.Saxer,S.M.Srinivas et al..In vivo burn depthdetermination by high-speed fiber-based polarization sensitiveoptical coherence tomography[J].Journal of Biomedical Optics,2001,6(4):474～479
15B.Cense,T.C.Chen,B.H.Park et al..In vivo depth-resolved birefringence measurements of the human retinal nervefiber layer by polarization-sensitive optical coherence tomography[J].Opt.Lett.,2002,27(18):1610～1612
16H.Kang,J.J.Jiao,C.Lee et al..Nondestructive assessmentof early tooth demineralization using cross-polarization opticalcoherence tomography[J].IEEE J.Selected Topics in QuantumElectronics,2010,16(4):870～876
17J.M.Schmitt,S.H.Xiang.Cross-polarized backscatter inoptical coherence tomography of biological tissue[J].Opt.Lett.,1998,23(13):1060～1062
18R.V.Kuranov,V.V.Sapozhnikova,I.V.Turchin et al..Complementary use of cross-polarization and standard OCT fordifferential diagnosis of pathological tissues[J].Opt.Express,2002,10(15):707～713
19Meng Zhuo,Liang Yu,Yao Xiaotianet al..In-line measurementand compensation for dispersion in OCT system[J].Journal ofOptoelectronics.Laser,2011,22(2):256～260孟卓,梁雨,姚晓天等.光学相干层析系统色散的在线测量及补偿[J].光电子.激光,2011,22(2):256～260
20V.M.Gelikonov,G.V.Gelikonov.New approach to cross-polarized optical coherence tomography based on orthogonal arbitrarilypolarized modes[J].Laser Physics Letters,2006,3(9):445～451
21Meng Zhuo,X.Steve Yao,Lan Shoufeng et al..Study ofautomatic elimination of polarization fluctuation method for all-fiber oral OCT system[J].Journal of Optoelectronics.Laser,2009,20(1):133～136孟卓,姚晓天,兰寿锋等.全光纤口腔OCT系统偏振波动自动消除方法研究[J].光电子.激光,2009,20(1):133～136
22Li Chen,Zhang Chunxi,Liang Sheng et al..Analysis ofpolarization dependence of fiber optic security systems[J].Journal of Beijing University of Aeronautics and Astronautics,2010,36(9):1099～1102李琛,张春熹,梁生等.干涉型光纤安防系统偏振误差机理分析[J].北京航空航天大学学报,2010,36(9):1099～1102
23M.C.Pierce,R.L.Sheridan,B.H.Park et al..Collagendenaturation can be quantified in burned human skin usingpolarization-sensitive optical coherence tomography[J].Burns,2004,30(6):511～517