磁共振冠状动脉成像新进展
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摘要
在过去的20年中,越来越多的研究关注于冠状动脉粥样硬化斑块的早期检测和监测。在几种成像方式中,磁共振成像(MRI)是一种很有前途的选择,其优点包括通用性、良好的软组织对比、斑块表征和缺乏电离辐射。在这篇综述中,我们将探讨多对比和多参数成像序列的最新进展,这些进展使冠状动脉管腔、管壁和斑块特征同步成像更接近临床。我们还讨论了分子磁共振和多模态动脉粥样硬化成像的最新进展。
In the past 20 years, more and more studies have focused on the early detection and monitoring of coronary atherosclerotic plaques.Magnetic resonance imaging(MRI) is a promising alternative to several imaging modalities, with advantages including versatility, good soft tissue contrast, plaque characterization, and lack of ionizing radiation.In this review, we will explore recent advances in multi-contrast and multi-parameter imaging sequences that bring synchronous imaging of coronary lumen, wall, and plaque features closer to clinical practice.We also discuss recent advances in molecular magnetic resonance imaging and multimodal atherosclerosis imaging.
In the past 20 years, more and more studies have focused on the early detection and monitoring of coronary atherosclerotic plaques.Magnetic resonance imaging(MRI) is a promising alternative to several imaging modalities, with advantages including versatility, good soft tissue contrast, plaque characterization, and lack of ionizing radiation.In this review, we will explore recent advances in multi-contrast and multi-parameter imaging sequences that bring synchronous imaging of coronary lumen, wall, and plaque features closer to clinical practice.We also discuss recent advances in molecular magnetic resonance imaging and multimodal atherosclerosis imaging.
引文
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[2]Adla T,Adlova R.Multimodality imaging of carotid stenosis.Int J Angiol.2015;24:179-184.
[3]Varnava AM,Mills PG,Davies MJ.Relationship between coronary artery remodeling and plaque vulnerability.Circulation.2002;105:939-943.
[4]Miao C,Chen S,Macedo R,et al.Positive remodeling of the coronary arteries detected by magnetic resonance imaging in an asymptomatic population:MESA(Multi-Ethnic Study of Atherosclerosis).J Am Coll Cardiol.2009;53:1708-1715.
[5]Cruz G,Atkinson D,Henningsson M,et al.Highly efficient nonrigid motion-corrected 3D whole-heart coronary vessel wall imaging.Magn Reson Med.2017;77:1894-1908.
[6]Xie Y,Kim YJ,Pang J,et al.Coronary atherosclerosis T1-weighed characterization with integrated anatomical reference:comparison with high-risk plaque features detected by invasive coronary imaging.JACC Cardiovasc Imaging.2017;10:637-648.
[7]Ginami G,Neji R,Phinikaridou A,et al.Simultaneous bright-and black-blood whole-heart MRI for noncontrast enhanced coronary lumen and thrombus visualization.Magn Reson Med.2018;79:1460-1472.
[8]Maintz D,Ozgun M,Hoffmeier A,et al.Selective coronary artery plaque visualization and differentiation by contrast-enhanced inversion prepared MRI.Eur Heart J.2006;27:1732-1736.