摘要
目的观察对自体富血小板凝胶治疗糖尿病足慢性溃疡的疗效。方法将糖尿病足慢性溃疡经4周常规治疗未愈的患者随机分为对照组和自体富血小板凝胶治疗组,观察6周内两组溃疡的治愈率和有效率的差异。结果与对照组比较,自体富血小板凝胶治疗组在糖尿病足慢性溃疡有效率差异具有统计学意义,治愈率差异无统计学意义,但两组平均治愈时间差异具有统计学意义。结论自体富血小板凝胶可有效改善wagner2-4级糖尿病足慢性溃疡预后,明显缩短治疗时间。其机制复杂,与抗菌性、抗炎性及调节组织基质金属蛋白酶活性有关。
引文
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