不同营养方式在结直肠癌根治术后的应用
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摘要
目的分析不同营养方式在结直肠癌根治术中的应用价值。方法选取2016年4月—2018年1月在山东省莱芜市人民医院肛肠外科实施结直肠癌根治术的108例患者,在获取患者知情同意后将之随机分为两组,各54例。观察组术后给予肠内营养支持,对照组术后给予肠外营养支持,比较两组恢复情况、营养相关指标及不良反应情况。结果治疗后,两组患者营养相关指标水平组间比较差异无统计学意义(P>0.05),不良反应发生率比较差异无统计学意义(P>0.05)。与对照组比较,观察组胃肠功能恢复时间、住院时间明显缩短,营养支持费用明显降低(P<0.05);术后7 d比较,观察组C反应蛋白、血前列腺素均明显低于对照组(P<0.05)。结论在结直肠癌根治术中,与肠外营养支持相比,肠内营养支持可缩短患者胃肠功能恢复时间与住院时间,减少营养支持费用,且可减轻机体炎症应激反应。
Objective To analyze the application value of different nutritional methods in radical resection of colorectal cancer. Methods A total of 108 patients who underwent radical resection of colorectal cancer in anorectal surgical department from April 2016 to January 2018 were randomly divided to 2 groups, 54 cases in each group. The observation group was given enteral nutrition support after operation, and the control group was given parenteral nutrition support. The recovery, nutrition related indicators and adverse reactions were compared between the two groups. Results After treatment, there was no significant difference between the two groups(P>0.05), and the incidence of adverse reactions had no significant differences(P>0.05).Compared with the control group, the recovery time and hospitalization time of the observation group were significantly shortened,and the nutritional support cost was significantly lower(P<0.05). Compared with the control group, the C-reactive protein and blood prostaglandin were significantly lower.(P<0.05). Conclusion In the radical resection of colorectal cancer, compared with parenteral nutrition support, enteral nutrition support can shorten the recovery time and hospitalization time of patients with gastrointestinal function, reduce the cost of nutritional support, and reduce the body's inflammatory stress response.
Objective To analyze the application value of different nutritional methods in radical resection of colorectal cancer. Methods A total of 108 patients who underwent radical resection of colorectal cancer in anorectal surgical department from April 2016 to January 2018 were randomly divided to 2 groups, 54 cases in each group. The observation group was given enteral nutrition support after operation, and the control group was given parenteral nutrition support. The recovery, nutrition related indicators and adverse reactions were compared between the two groups. Results After treatment, there was no significant difference between the two groups(P>0.05), and the incidence of adverse reactions had no significant differences(P>0.05).Compared with the control group, the recovery time and hospitalization time of the observation group were significantly shortened,and the nutritional support cost was significantly lower(P<0.05). Compared with the control group, the C-reactive protein and blood prostaglandin were significantly lower.(P<0.05). Conclusion In the radical resection of colorectal cancer, compared with parenteral nutrition support, enteral nutrition support can shorten the recovery time and hospitalization time of patients with gastrointestinal function, reduce the cost of nutritional support, and reduce the body's inflammatory stress response.
引文
[1]肖永彪,贺宇琴.结直肠癌各分期的营养风险评分和相应营养支持与术后并发症的关系分析[J].医学临床研究,2016,33(6):1236-1238.
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[9]申连东,齐文海.术前营养风险与直肠癌前切除术后吻合口漏的相关性分析[J].中国普外基础与临床杂志,2016,8(4):454-457.
[10]操志方.直肠癌根治术前应用免疫增强型肠内营养对患者术后免疫应答水平及创伤耐受能力的影响[J].海南医学院学报,2017,23(4):521-524.
[11]傅华军,张少林,陈卉颖,等.结直肠癌术后切口感染与机体营养状态、免疫功能及炎性因子的关系[J].海南医学院学报,2017,23(7):921-924.
[12]Ma傅华军,张V,Bezd傅华军K,Foltys A,et al. The Impact of High Protein Nutritional Support on Clinical Outcomes and Treatment Costs of Patients with Colorectal Cancer[J]. Klin Onkol,2016,29(5):351-357.
[13]章晓璟,孙鑫荣,朱炜,等.早期肠内营养对结直肠癌术后机体免疫、早期康复及并发症的影响[J].临床药物治疗杂志,2016,14(1):39-42.
[14]秦禄武,何龙海.直肠癌术后早期肠内营养对预防肠梗阻的效果分析[J].实用癌症杂志,2016,31(12):2041-2043.
[15]谢永灿,邢专.腹腔镜结直肠癌根治术后两种营养支持途径的疗效对比[J].新医学,2017,48(7):482-486.
[2]周军,杨斌,张育超,等.老年结直肠癌腹腔镜根治术后早期肠内营养的快速康复价值分析[J].临床和实验医学杂志,2016,13(13):1253-1256.
[3]杜一鸿,刘云莉,李明杰.术前营养支持对腹腔镜结直肠癌根治术后免疫功能和并发症的影响[J].河北医药,2017,39(21):3258-3260.
[4]张正君,方可,李光耀.术前营养状态相关指标与结直肠癌根治术患者预后的关系[J].山东医药,2017,57(30):90-92.
[5]张明,朱信强,丁闯,等.结直肠癌患者术后预后营养指数在预后评估中的应用[J].实用肿瘤学杂志,2017,31(2):131-136.
[6]Wang Y,Zheng J,Gao Z,et al. Investigation on nutritional risk assessment and nutritional support status of surgical patients with colorectal cancer[J].J BUON,2018,23(1):62-67.
[7]章晓璟,孙鑫荣,朱炜,等.早期肠内营养对结直肠癌术后机体免疫、早期康复及并发症的影响[J].临床药物治疗杂志,2016,14(1):39-42.
[8]胡德升,董星,杨松鹏,等.术前营养不良对结直肠癌患者术后感染及免疫功能的影响[J].中华医院感染学杂志,2017,27(24):5626-5629.
[9]申连东,齐文海.术前营养风险与直肠癌前切除术后吻合口漏的相关性分析[J].中国普外基础与临床杂志,2016,8(4):454-457.
[10]操志方.直肠癌根治术前应用免疫增强型肠内营养对患者术后免疫应答水平及创伤耐受能力的影响[J].海南医学院学报,2017,23(4):521-524.
[11]傅华军,张少林,陈卉颖,等.结直肠癌术后切口感染与机体营养状态、免疫功能及炎性因子的关系[J].海南医学院学报,2017,23(7):921-924.
[12]Ma傅华军,张V,Bezd傅华军K,Foltys A,et al. The Impact of High Protein Nutritional Support on Clinical Outcomes and Treatment Costs of Patients with Colorectal Cancer[J]. Klin Onkol,2016,29(5):351-357.
[13]章晓璟,孙鑫荣,朱炜,等.早期肠内营养对结直肠癌术后机体免疫、早期康复及并发症的影响[J].临床药物治疗杂志,2016,14(1):39-42.
[14]秦禄武,何龙海.直肠癌术后早期肠内营养对预防肠梗阻的效果分析[J].实用癌症杂志,2016,31(12):2041-2043.
[15]谢永灿,邢专.腹腔镜结直肠癌根治术后两种营养支持途径的疗效对比[J].新医学,2017,48(7):482-486.