玉屏风汤联合针灸治疗变应性鼻炎临床研究
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摘要
目的:探讨玉屏风汤联合针灸治疗变应性鼻炎的疗效及安全性。方法:选取我院收治的变应性鼻炎患者120例,根据治疗方法不同分成两组。对照组应用常规针灸法治疗,研究组应用玉屏风汤联合针灸治疗,对比两组患者治疗结果及对患者的安全性进行分析。结果:研究组患者有效率显著高于对照组(P<0.05)。研究组患者的不良反应发生率明显低于对照组(P<0.05)。治疗前两组患者的各项症状、体征无统计学差异(P>0.05),治疗后研究组患者的症状、体征总积分明显高于对照组(P<0.05)。结论:在变应性鼻炎患者进行治疗的同时,对其采用玉屏风汤联合针灸辅助治疗,其临床效果较为理想,同时可显著降低患者的不良反应发生率,改善患者的各项血清学指标,以进一步改善患者的生活质量,延长患者的生存周期。
Objective: To investigate the efficacy and safety of Yupingfeng decoction combined with acupuncture and moxibustion in the treatment of allergic rhinitis. Methods: 120 patients with allergic rhinitis in our hospital were divided into two groups according to different treatment methods, the control group used conventional acupuncture treatment, the study group used Yupingfeng decoction combined with acupuncture treatment, compared two groups of patients and treatment results of patient safety. Results: The effective rate of the study group was significantly higher than that of the control group(P<0.05). The incidence of adverse reactions in the study group was significantly lower than that of the control group(P<0.05). There was no significant difference in the symptoms and signs between the two groups before treatment(P>0.05), total score of symptoms and signs in the study group after treatment. It was significantly higher than that in the control group(P<0.05). Conclusion: Paticrts with allergic rhinitis were being treated, the Yupingfeng decoction combined with acupuncture and moxibustion was an effective adjuvant therapy, which can significantly reduce the incidence of adverse reactions and improve the serological indicators of the patients, so as to further improve the quality of life of the patients and prolong the life cycle of the patients.
Objective: To investigate the efficacy and safety of Yupingfeng decoction combined with acupuncture and moxibustion in the treatment of allergic rhinitis. Methods: 120 patients with allergic rhinitis in our hospital were divided into two groups according to different treatment methods, the control group used conventional acupuncture treatment, the study group used Yupingfeng decoction combined with acupuncture treatment, compared two groups of patients and treatment results of patient safety. Results: The effective rate of the study group was significantly higher than that of the control group(P<0.05). The incidence of adverse reactions in the study group was significantly lower than that of the control group(P<0.05). There was no significant difference in the symptoms and signs between the two groups before treatment(P>0.05), total score of symptoms and signs in the study group after treatment. It was significantly higher than that in the control group(P<0.05). Conclusion: Paticrts with allergic rhinitis were being treated, the Yupingfeng decoction combined with acupuncture and moxibustion was an effective adjuvant therapy, which can significantly reduce the incidence of adverse reactions and improve the serological indicators of the patients, so as to further improve the quality of life of the patients and prolong the life cycle of the patients.
引文
[1] 马岩, 王金昌, 王树鹏.小青龙汤联合玉屏风散对变应性鼻炎大鼠AQP5、NF-κB p65和p-CREB表达的影响[J].环球中医药,2016, 9(11):1318-1322.
[2] Wang B, Liu H T. Clinical observation of mahuang lianqiao Chixiaodou decoction combined with acupuncture and moxibustion in treating 61 cases with allergic rhinitis[J]. Chinese Journal of Experimental Traditional Medical Formulae, 2015,12(23):1123-1125.
[3] 王金昌,马岩,王树鹏.基于NF-κB信号通路探讨小青龙汤合玉屏风散对变应性鼻炎大鼠MUC5AC和MUC5B表达的影响[J].辽宁中医药大学学报,2016,12(6):16-18.
[4] 马兆楠,王金昌,马岩,等.基于NF-κB信号通路探讨小青龙汤合玉屏风散对变应性鼻炎大鼠TNF-α和TNF-α mRNA表达影响[J].辽宁中医药大学学报,2017,35(4):18-20.
[5] Tao J. The clinical research on Huoluo Xiaobi decoction fumigation combined with acupuncture and moxibustion in the treatment of neck shoulder pain or lumbocrural pain[J]. Chinese Medicine Modern Distance Education of China, 2016,14(12):114-121.
[6] 陈庆利,王会民,汤智平,等.氯雷他定片联合小青龙汤加减治疗非变应性鼻炎疗效及对TNF-α和IL-4水平的影响[J].现代中西医结合杂志,2017,26(12):1351-1352.
[7] 贺莉,曹建英,侯明滨.穿心莲内酯滴丸联合丹溪玉屏风颗粒对变应性鼻炎患儿免疫功能的影响[J].中国药房,2017,28(5):643-645.
[8] Wang Lei.Zhilei in the treatment of allergic rhinitis by using warming Yang for inducing resuscitation method[J]. Guangming Journal of Chinese Medicine, 2015,13(34):134-146.
[9] 任蓉,陈鹏,段学军.鼻腔冲洗治疗变应性鼻炎36例[J].陕西医学杂志,2016, 45(10):1385-1386.
[10] 史红健,邵渝,何迎春,等.加味补中益气汤对变应性鼻炎大鼠鼻腔黏膜P物质及P物质受体表达活性的影响[J].中华中医药杂志,2015,14(3):918-920.
[11] 史军,刘玉.消风宣窍汤联合鼻用激素治疗变应性鼻炎近期疗效及对血清EOS、CSF水平和免疫细胞功能的影响[J].中国中医急症,2017,13(11):1887-1890.
[12] Zhou W, Ming L I, Ouyang Z. The clinical experience of professor ouyang Tian J. Bushen anshen decoction combined with acupuncture and moxibustion in the treatment of insomnia of Yin deficiency of liver and kidney for 57 Cases[J]. Guangming Journal of Chinese Medicine, 2017.
[13] 陈艳洋,曾莺,邓丽莎.培元生金通窍汤联合西药治疗儿童支气管哮喘合并变应性鼻炎疗效观察[J].海南医学,2016,27(24):4039-4041.
[14] 李海霞,屈凤勤,李梅生,等.通窍止鼽汤联合西替利嗪治疗变应性鼻炎及对TNF-α和IL-4水平的影响[J].陕西中医,2017, 38(2):240-241.
[15] Ming L I, Neurology D O, Hospital C P. Observation on the curative effect of Tongluo Fuzheng decoction combined with acupuncture and moxibustion on Hemiplegia after ischemic stroke[J]. China Continuing Medical Education, 2017,17(23):134-147.
[2] Wang B, Liu H T. Clinical observation of mahuang lianqiao Chixiaodou decoction combined with acupuncture and moxibustion in treating 61 cases with allergic rhinitis[J]. Chinese Journal of Experimental Traditional Medical Formulae, 2015,12(23):1123-1125.
[3] 王金昌,马岩,王树鹏.基于NF-κB信号通路探讨小青龙汤合玉屏风散对变应性鼻炎大鼠MUC5AC和MUC5B表达的影响[J].辽宁中医药大学学报,2016,12(6):16-18.
[4] 马兆楠,王金昌,马岩,等.基于NF-κB信号通路探讨小青龙汤合玉屏风散对变应性鼻炎大鼠TNF-α和TNF-α mRNA表达影响[J].辽宁中医药大学学报,2017,35(4):18-20.
[5] Tao J. The clinical research on Huoluo Xiaobi decoction fumigation combined with acupuncture and moxibustion in the treatment of neck shoulder pain or lumbocrural pain[J]. Chinese Medicine Modern Distance Education of China, 2016,14(12):114-121.
[6] 陈庆利,王会民,汤智平,等.氯雷他定片联合小青龙汤加减治疗非变应性鼻炎疗效及对TNF-α和IL-4水平的影响[J].现代中西医结合杂志,2017,26(12):1351-1352.
[7] 贺莉,曹建英,侯明滨.穿心莲内酯滴丸联合丹溪玉屏风颗粒对变应性鼻炎患儿免疫功能的影响[J].中国药房,2017,28(5):643-645.
[8] Wang Lei.Zhilei in the treatment of allergic rhinitis by using warming Yang for inducing resuscitation method[J]. Guangming Journal of Chinese Medicine, 2015,13(34):134-146.
[9] 任蓉,陈鹏,段学军.鼻腔冲洗治疗变应性鼻炎36例[J].陕西医学杂志,2016, 45(10):1385-1386.
[10] 史红健,邵渝,何迎春,等.加味补中益气汤对变应性鼻炎大鼠鼻腔黏膜P物质及P物质受体表达活性的影响[J].中华中医药杂志,2015,14(3):918-920.
[11] 史军,刘玉.消风宣窍汤联合鼻用激素治疗变应性鼻炎近期疗效及对血清EOS、CSF水平和免疫细胞功能的影响[J].中国中医急症,2017,13(11):1887-1890.
[12] Zhou W, Ming L I, Ouyang Z. The clinical experience of professor ouyang Tian J. Bushen anshen decoction combined with acupuncture and moxibustion in the treatment of insomnia of Yin deficiency of liver and kidney for 57 Cases[J]. Guangming Journal of Chinese Medicine, 2017.
[13] 陈艳洋,曾莺,邓丽莎.培元生金通窍汤联合西药治疗儿童支气管哮喘合并变应性鼻炎疗效观察[J].海南医学,2016,27(24):4039-4041.
[14] 李海霞,屈凤勤,李梅生,等.通窍止鼽汤联合西替利嗪治疗变应性鼻炎及对TNF-α和IL-4水平的影响[J].陕西中医,2017, 38(2):240-241.
[15] Ming L I, Neurology D O, Hospital C P. Observation on the curative effect of Tongluo Fuzheng decoction combined with acupuncture and moxibustion on Hemiplegia after ischemic stroke[J]. China Continuing Medical Education, 2017,17(23):134-147.