梅花鹿鹿茸的质量分析及开发利用
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摘要
梅花鹿茸是我国传统名贵中药,使得在国内的中药材市场上伪劣品、混淆品越来越多。研究表明,粗蛋白、Ca、P、Na、Fe、Ba、Sr、谷氨酸及甘氨酸是鹿茸的特征成分,与鹿茸品质特征密切相关。完善鹿茸鉴定方法,建立综合评价鹿茸质量以及对梅花鹿鹿茸的开发与利用有着极其深远的意义。系统阐述了梅花鹿鹿茸的质量评价及开发利用,为梅花鹿鹿茸的进一步研究及应用提供借鉴。
Sika deer antlers is a traditional Chinese medicine.It is expensive and need more in the market,more and more fake and confused antlers are selling in Chinese herbal medicine market.The crude protein,Ca,P,Na,Fe,Ba,Sr,glutamic acid and glycine are the characteristic components of antlers in previous research,which are closely related to the quality characteristics of antlers.So the improvement of antler's identification method,the comprehensive evaluation of the quality and the research utilization of deer antler are very significant.This paper systematically expounds the quality evaluation,development and utilization of the deer antlers and provide reference for the further research and application of the deer antler.
Sika deer antlers is a traditional Chinese medicine.It is expensive and need more in the market,more and more fake and confused antlers are selling in Chinese herbal medicine market.The crude protein,Ca,P,Na,Fe,Ba,Sr,glutamic acid and glycine are the characteristic components of antlers in previous research,which are closely related to the quality characteristics of antlers.So the improvement of antler's identification method,the comprehensive evaluation of the quality and the research utilization of deer antler are very significant.This paper systematically expounds the quality evaluation,development and utilization of the deer antlers and provide reference for the further research and application of the deer antler.
引文
[1]邢博.西藏马鹿和东北马鹿营养适应对策比较研究[D].哈尔滨:东北林业大学,2016.
[2]丁玉华.鹿茸的角[J].野生动物,1998,19(01):11-13.
[3]赵守训等.中药辞海(第三卷)[M].北京:中国医药科技出版社,1997:519-525.
[4]侯召华,刘畅,任贵兴.煮炸和冷冻干燥鹿茸中脂溶性成分及色差研究[J].现代食品科技,2017,10(33):1-8.
[5]胡太超,刘玉敏,陶荣珊,等.鹿茸多肤的抗疲劳作用机制研究[J].吉林农业大学学报,2015,37(04):469-475.
[6]ZHOU Q L,GUO Y J,WANG L J,et al.Velvet antler polypeptidespromoted proliferation of chondrocytes and osteoblast precursors andfracture healing[J].Acta Phannacologica Sinica,1999,20(03):279-282.
[7]国家药典委员会.中华人民共和国药典[S].一部.北京:中国医药科技出版社,2010:303.
[8]杨若明,张经华,张林源,等.麋鹿茸、马鹿茸和梅花鹿茸营养成分的分析比较研究[J].广东微量元素科学,2000,7(12):47-51.
[9]李淑芳.花马杂交鹿茸多种营养成分的主成分测定探析[J].北方药学,2014,11(04):7.
[10]赵磊,李继海,朱大洲,等.5种鹿茸营养成分的主成分分析[J].光谱学与光谱分析,2010,30(09):2571-2575.
[11]Suttie J M.Insulin-like growth factor I(IGF-I)antler stimulating hormone[J].Journal of Endocrinology,1985,116(02):846.
[12]Price J,Allen S.Exploring the mechanisms regulating re-generation of deer antlers[J].Philosophical Transactions of the Royal Society of London.Series B,Biological Sciences,2004,259(1445):809.
[13]李仁宽,曾志森,林娟,等.梅花鹿超氧化歧化酶的克隆与原核表达[J].生物技术,2010,20(04):9-12.
[14]Tseng S H,Sung C H,Chen L G,et al.Comparison of chemical compositions and osteoprotective effects of different sections of velvet antler[J].Journal of Ethnopharmacology,2014,151(01):352-360.
[15]张树臣.鹿茸的化学、药理及临床应用[J].吉林中医药,1981(03);48-50.
[16]赵蒙.东北马鹿乌兰坝品种鹿茸化学成分分析报告[J].经济动物学报,1999,3(01):28-34.
[17]王静竹,陈定一,薛岚.鹿茸与鹿角中氨基酸含量测定[J].中药材,1990(10):13-14.
[18]何琴.鹿茸及其伪品的性状鉴别[J].实用中医药杂志,2017,9(33):1102-1103.
[19]陈代贤,郭秋月,任伟,等.11种鹿茸显微组织特征比较鉴别[J].中药材,2000,23(12):743-746.
[20]刘丽,曲静,包辉,等.六种鹿茸茸毛的显微特征比较鉴别[J].辽宁中医杂志,2008,35(06):906-908.
[21]魏晓明,陈代贤,郭月秋.鹿角及八种类似品的显微组织比较鉴别[J].中药材2004,27(04):246-249.
[22]安宏,谭照龙,杨桂芹.用紫外光谱法对鹿茸质量的比较鉴别[J].黑龙江医药,2000,13(04):222.
[23]张丽,王树春,吴云山,等.马鹿茸的X射线衍射Fourier指纹图谱鉴定[J].中成药,2005(05):577-580.
[24]丁倩男,王春梅,戴俊东,等.梅花鹿鹿茸不同部位蛋白双向电泳谱图比[J].中药材,2013,36(04):521-525.
[25]朱云飞,初正云,李洪江,等.SDS-PAGE凝胶电泳法对不同种鹿茸蛋白质差异化研究[J].2017,19(03):48-50.
[26]董思敏.鹿茸鹿源及梅花鹿茸品质评价体系的建立[D].长春:吉林农业大学,2016.
[27]陈建南.鹿茸资源的综合开发利用[J].福建中医药,1988(03):39-40.
[28]陈艳霞.马鹿(Cervus elaphus)鹿茸快速生长期生长点软骨和茸皮组织microRNA表达谱研究[D].哈尔滨:东北林业大学,2016.
[29]Billingham RE,Mangold R,Silvers K.The neogenesis of skin in the antlers of deer[J].Annals of the New York Academy of Sciences,1959,83:491-8.
[30]Li C.Exploration of the mechanism underlying neogenesis and regeneration of postnatal l mammalian skin:deer antler velvet[J].International Journal of Medical and Biologica Frontiers,2010,16(11/12):1-19.
[31]高其品,仲崇林,张大军.鹿茸胶中磷脂类成分分析[J].中国中药杂志,1993(06):360-361.
[32]宗颖,张辉,牛晓晖,等.梅花鹿茸生物碱类成分及其对小鼠脾细胞增殖的影响[J].中药材,2014,37(05):752-755.
[33]吉静娴,钱璟,黄凤杰,等.鹿茸的活性物质及药理作用的研究进展[J].中国生化药物杂志,2009,30(02):141-143.
[34]齐艳萍.鹿茸的化学成分及对肝损伤的修复作用[J].甘肃中医,2010,23(01):61-63.
[35]Zhou R,Li S F.Supercritical carbon dioxide and co-solventextractions of estradiol and progesterone from antler velvet[J].Journal of Food Composition and Analysis,2009,22:72-78.
[36]杨秀伟,白云鹏.马鹿茸化学成分的研究[J].中草药,1994,25(05):229-231.
[37]杨若明,张经华,蓝叶芬.固相萃取-毛细管电泳法测定麋鹿茸中的性激素[J].现代仪器,2005(01):25-27.
[38]Suttie J M.Insulin-like growth factor I(IGF-I)antler stimulating hormone[J].Journal of Endocrinolc,1985,116(02):846.
[39]Price J,Allen S.Exploring the mechanisms regulating re-generation of deer antlers[J].Philosoph Transactions of the Royal Society of London.Series B,Biological Sciences,2004,259(1445):809.
[40]李和平.中国茸鹿品种的鹿茸化学成分[J].东北林业大学学报,2003,31(04):26-28.
[41]汪树理,孙继红,李晓红,等.东北梅花鹿茸不同部位多糖与无机元素质量分数的差异[J].东北林业大学学报,2008,36(05):58,66.
[2]丁玉华.鹿茸的角[J].野生动物,1998,19(01):11-13.
[3]赵守训等.中药辞海(第三卷)[M].北京:中国医药科技出版社,1997:519-525.
[4]侯召华,刘畅,任贵兴.煮炸和冷冻干燥鹿茸中脂溶性成分及色差研究[J].现代食品科技,2017,10(33):1-8.
[5]胡太超,刘玉敏,陶荣珊,等.鹿茸多肤的抗疲劳作用机制研究[J].吉林农业大学学报,2015,37(04):469-475.
[6]ZHOU Q L,GUO Y J,WANG L J,et al.Velvet antler polypeptidespromoted proliferation of chondrocytes and osteoblast precursors andfracture healing[J].Acta Phannacologica Sinica,1999,20(03):279-282.
[7]国家药典委员会.中华人民共和国药典[S].一部.北京:中国医药科技出版社,2010:303.
[8]杨若明,张经华,张林源,等.麋鹿茸、马鹿茸和梅花鹿茸营养成分的分析比较研究[J].广东微量元素科学,2000,7(12):47-51.
[9]李淑芳.花马杂交鹿茸多种营养成分的主成分测定探析[J].北方药学,2014,11(04):7.
[10]赵磊,李继海,朱大洲,等.5种鹿茸营养成分的主成分分析[J].光谱学与光谱分析,2010,30(09):2571-2575.
[11]Suttie J M.Insulin-like growth factor I(IGF-I)antler stimulating hormone[J].Journal of Endocrinology,1985,116(02):846.
[12]Price J,Allen S.Exploring the mechanisms regulating re-generation of deer antlers[J].Philosophical Transactions of the Royal Society of London.Series B,Biological Sciences,2004,259(1445):809.
[13]李仁宽,曾志森,林娟,等.梅花鹿超氧化歧化酶的克隆与原核表达[J].生物技术,2010,20(04):9-12.
[14]Tseng S H,Sung C H,Chen L G,et al.Comparison of chemical compositions and osteoprotective effects of different sections of velvet antler[J].Journal of Ethnopharmacology,2014,151(01):352-360.
[15]张树臣.鹿茸的化学、药理及临床应用[J].吉林中医药,1981(03);48-50.
[16]赵蒙.东北马鹿乌兰坝品种鹿茸化学成分分析报告[J].经济动物学报,1999,3(01):28-34.
[17]王静竹,陈定一,薛岚.鹿茸与鹿角中氨基酸含量测定[J].中药材,1990(10):13-14.
[18]何琴.鹿茸及其伪品的性状鉴别[J].实用中医药杂志,2017,9(33):1102-1103.
[19]陈代贤,郭秋月,任伟,等.11种鹿茸显微组织特征比较鉴别[J].中药材,2000,23(12):743-746.
[20]刘丽,曲静,包辉,等.六种鹿茸茸毛的显微特征比较鉴别[J].辽宁中医杂志,2008,35(06):906-908.
[21]魏晓明,陈代贤,郭月秋.鹿角及八种类似品的显微组织比较鉴别[J].中药材2004,27(04):246-249.
[22]安宏,谭照龙,杨桂芹.用紫外光谱法对鹿茸质量的比较鉴别[J].黑龙江医药,2000,13(04):222.
[23]张丽,王树春,吴云山,等.马鹿茸的X射线衍射Fourier指纹图谱鉴定[J].中成药,2005(05):577-580.
[24]丁倩男,王春梅,戴俊东,等.梅花鹿鹿茸不同部位蛋白双向电泳谱图比[J].中药材,2013,36(04):521-525.
[25]朱云飞,初正云,李洪江,等.SDS-PAGE凝胶电泳法对不同种鹿茸蛋白质差异化研究[J].2017,19(03):48-50.
[26]董思敏.鹿茸鹿源及梅花鹿茸品质评价体系的建立[D].长春:吉林农业大学,2016.
[27]陈建南.鹿茸资源的综合开发利用[J].福建中医药,1988(03):39-40.
[28]陈艳霞.马鹿(Cervus elaphus)鹿茸快速生长期生长点软骨和茸皮组织microRNA表达谱研究[D].哈尔滨:东北林业大学,2016.
[29]Billingham RE,Mangold R,Silvers K.The neogenesis of skin in the antlers of deer[J].Annals of the New York Academy of Sciences,1959,83:491-8.
[30]Li C.Exploration of the mechanism underlying neogenesis and regeneration of postnatal l mammalian skin:deer antler velvet[J].International Journal of Medical and Biologica Frontiers,2010,16(11/12):1-19.
[31]高其品,仲崇林,张大军.鹿茸胶中磷脂类成分分析[J].中国中药杂志,1993(06):360-361.
[32]宗颖,张辉,牛晓晖,等.梅花鹿茸生物碱类成分及其对小鼠脾细胞增殖的影响[J].中药材,2014,37(05):752-755.
[33]吉静娴,钱璟,黄凤杰,等.鹿茸的活性物质及药理作用的研究进展[J].中国生化药物杂志,2009,30(02):141-143.
[34]齐艳萍.鹿茸的化学成分及对肝损伤的修复作用[J].甘肃中医,2010,23(01):61-63.
[35]Zhou R,Li S F.Supercritical carbon dioxide and co-solventextractions of estradiol and progesterone from antler velvet[J].Journal of Food Composition and Analysis,2009,22:72-78.
[36]杨秀伟,白云鹏.马鹿茸化学成分的研究[J].中草药,1994,25(05):229-231.
[37]杨若明,张经华,蓝叶芬.固相萃取-毛细管电泳法测定麋鹿茸中的性激素[J].现代仪器,2005(01):25-27.
[38]Suttie J M.Insulin-like growth factor I(IGF-I)antler stimulating hormone[J].Journal of Endocrinolc,1985,116(02):846.
[39]Price J,Allen S.Exploring the mechanisms regulating re-generation of deer antlers[J].Philosoph Transactions of the Royal Society of London.Series B,Biological Sciences,2004,259(1445):809.
[40]李和平.中国茸鹿品种的鹿茸化学成分[J].东北林业大学学报,2003,31(04):26-28.
[41]汪树理,孙继红,李晓红,等.东北梅花鹿茸不同部位多糖与无机元素质量分数的差异[J].东北林业大学学报,2008,36(05):58,66.