社交能力训练对精神分裂症患者认知功能的影响
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摘要
目的研究社交能力训练对精神分裂症患者认知功能的影响。方法选择2016年9月至2018年5月我院收治的150例精神分裂症患者作为观察组,另选择70例健康体检者作为对照组,比较两组的认知功能。根据治疗方式的不同将观察组分为观察1组(常规抗精神病药物治疗)和观察2组(常规抗精神病药物+社交能力训练治疗),各75例。比较观察组患者的认知功能及治疗效果。结果治疗前,观察组的PRM、IED、SWM及RVP各项数据与对照组比较,差异有统计学意义(P<0.05)。治疗后,观察2组患者的阳性量表、阴性量表、一般精神病理量表评分及总分均低于观察1组(P<0.05);观察2组的PRM测试中的平均潜伏时间、SWM测试中的总搜索错误数和策略分、RVP测试中的正确反应延迟时间、错误报警率明显优于观察1组,差异有统计学意义(P<0.05)。结论精神分裂症患者的认知功能均低于正常人,在常规抗精神病药物治疗的基础上联合社交能力训练能明显改善患者的阳性与阴性症状,提高部分认知功能。
Objective To observe the effect of social ability training on cognitive function of schizophrenic patients.Methods From Sepertember 2016 to May 2018, 150 patients with schizophrenia were selected as observation group, and 70 health examiners were selected as control group. The cognitive function between the two groups were compared. The observation group were divided into observation group 1(treated with routine antipsychotic drugs) and observation group 2(treated with routine antipsychotic drugs+social ability training) according to the different treatment methods, with 75 cases in each group. The cognitive function and therapeutic effects between the two groups were compared. Results Before treatment, the data of PRM, IED, SWM and RVP in the observation group were significantly different from those in the control group(P<0.05). After treatment, the positive evaluation sheet, negative evaluation sheet, general psychopathological evaluation sheet scores and total scores of the observation group 2 were lower than those of the observation group 1(P<0.05). The average latency in the PRM test, the total number of search errors and strategy score in the SWM test, and the correct response delay time and error alarm rate in the RVP in the observation group 2 were significantly better than those in the observation group 1, the differences were statistically significant(P<0.05). Conclusion The cognitive function of patients with schizophrenia is lower than that of the normal people. Routin eantipsychotic drugs combined with social ability training can significantly improve the positive and negative symptoms of schizophrenia patients, and improve some cognitive functions.
Objective To observe the effect of social ability training on cognitive function of schizophrenic patients.Methods From Sepertember 2016 to May 2018, 150 patients with schizophrenia were selected as observation group, and 70 health examiners were selected as control group. The cognitive function between the two groups were compared. The observation group were divided into observation group 1(treated with routine antipsychotic drugs) and observation group 2(treated with routine antipsychotic drugs+social ability training) according to the different treatment methods, with 75 cases in each group. The cognitive function and therapeutic effects between the two groups were compared. Results Before treatment, the data of PRM, IED, SWM and RVP in the observation group were significantly different from those in the control group(P<0.05). After treatment, the positive evaluation sheet, negative evaluation sheet, general psychopathological evaluation sheet scores and total scores of the observation group 2 were lower than those of the observation group 1(P<0.05). The average latency in the PRM test, the total number of search errors and strategy score in the SWM test, and the correct response delay time and error alarm rate in the RVP in the observation group 2 were significantly better than those in the observation group 1, the differences were statistically significant(P<0.05). Conclusion The cognitive function of patients with schizophrenia is lower than that of the normal people. Routin eantipsychotic drugs combined with social ability training can significantly improve the positive and negative symptoms of schizophrenia patients, and improve some cognitive functions.
引文
[1]翁永振.精神分裂症的康复操作手册[M].北京:人民卫生出版社,2009.
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[3]段浠婷,刘春宇,赵晶晶.精神分裂症认知功能障碍综述[J].国际精神病学杂志,2018,45(3):388-391.
[4]张菁,袁国桢,周振和,等.社交技能训练对慢性精神分裂症患者社会认知功能的影响[J].精神医学杂志,2017,30(1):42-44.
[5] YING J,ANA A,AMANDA MC,et al.Homocysteine levels impact directly on epigenetic reprogramming in astrocytes[J].Neurochem Int,2011,58(7):833-838.
[6] SHARMA A.Cambridge neuropsychological test automated battery[M].Encyclopedia of Autism Spectrum Disorders,2013:498-515.
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[8]徐逸,陆峥.精神分裂症患者认知功能障碍评估与治疗[J].世界临床药物,2016,32(1):8-12.
[9]莫霞.精神分裂症临床研究疗效及安全性评估量表使用情况分析[D].广州:暨南大学,2015.
[2]卓恺明,陆峥.精神分裂症患者认知训练治疗的原则、方法及展望[J].中国心理卫生杂志,2017,31(10):793-797.
[3]段浠婷,刘春宇,赵晶晶.精神分裂症认知功能障碍综述[J].国际精神病学杂志,2018,45(3):388-391.
[4]张菁,袁国桢,周振和,等.社交技能训练对慢性精神分裂症患者社会认知功能的影响[J].精神医学杂志,2017,30(1):42-44.
[5] YING J,ANA A,AMANDA MC,et al.Homocysteine levels impact directly on epigenetic reprogramming in astrocytes[J].Neurochem Int,2011,58(7):833-838.
[6] SHARMA A.Cambridge neuropsychological test automated battery[M].Encyclopedia of Autism Spectrum Disorders,2013:498-515.
[7]马婉.精神症状评定量表的信效度再检验及临床应用优势[D].杭州:浙江大学,2015.
[8]徐逸,陆峥.精神分裂症患者认知功能障碍评估与治疗[J].世界临床药物,2016,32(1):8-12.
[9]莫霞.精神分裂症临床研究疗效及安全性评估量表使用情况分析[D].广州:暨南大学,2015.