增强型体外反搏术治疗不稳定型心绞痛的临床疗效系统评价
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摘要
目的探索增强型体外反搏术对不稳定型心绞痛的临床疗效。方法计算机检索Pub Med、VIP、CNKI和万方数据库,查找增强型体外反搏术治疗不稳定型心绞痛的随机对照试验(RCT),自建库至2017年6月30日时限内文献均纳入检索范围。并对纳入文献的参考文献进行手工检索。按纳入排除标准由两人独立进行RCT的筛选、资料提取和质量评价后,采用Rev Man 5.3软件进行Meta分析。结果共纳入14个研究,1365例患者。Meta分析结果显示,增强型体外反搏术联合常规治疗在不稳定型心绞痛的心绞痛症状(RR=1.31,95%CI:1.22~1.41,P<0.00001)和心电图改善方面(RR=1.23,95%CI:1.12~1.35,P<0.0001)优于常规治疗。结论增强型体外反搏术治疗不稳定型心绞痛的临床疗效是确切的,且安全性高。
Objective To investigate the clinical efficacy of Enhanced external counterpulsation(EECP) on unstable angina pectoris(UAP). Methods The databases of Pub Med, VIP, CNKI and Wan Fang Data were retrieved with computer for searching the randomized controlled trials(RCT) about treatment of UAP with EECP from establishment time of the databases to June 30, 2017. The references of enclosed RCT were retrieved manually. The RCT were screened, extracted and reviewed on quality by 2 persons independently according to inclusion and exclusion criteria, and given Meta-analysis by using Rev Man 5.3 software. Results There were totally 14 RCT included involved 1365 patients. The results of Meta-analysis showed that EECP combined with routine therapy was superior to single routine therapy in relieving UAP symptoms(RR=1.31, 95%CI: 1.22~1.41, P<0.00001) and ECG improvement(RR=1.23, 95%CI: 1.12~1.35, P<0.0001). Conclusion EECP has reliable clinical efficacy and higher safety in treatment of UAP.
Objective To investigate the clinical efficacy of Enhanced external counterpulsation(EECP) on unstable angina pectoris(UAP). Methods The databases of Pub Med, VIP, CNKI and Wan Fang Data were retrieved with computer for searching the randomized controlled trials(RCT) about treatment of UAP with EECP from establishment time of the databases to June 30, 2017. The references of enclosed RCT were retrieved manually. The RCT were screened, extracted and reviewed on quality by 2 persons independently according to inclusion and exclusion criteria, and given Meta-analysis by using Rev Man 5.3 software. Results There were totally 14 RCT included involved 1365 patients. The results of Meta-analysis showed that EECP combined with routine therapy was superior to single routine therapy in relieving UAP symptoms(RR=1.31, 95%CI: 1.22~1.41, P<0.00001) and ECG improvement(RR=1.23, 95%CI: 1.12~1.35, P<0.0001). Conclusion EECP has reliable clinical efficacy and higher safety in treatment of UAP.
引文
[1]翁锦龙,郑直,段晓巧,等.增强型体外反搏联合中医辩证治疗不稳定性心绞痛疗效观察[J].中国继续医学教育,2015,7(1):180-1.
[2]孟艳玲,高建军.增强型体外反搏对于冠心病不稳定型心绞痛患者心绞痛持续时间、硝酸甘油用量的影响[J].养生保健指南,2016(22):2.
[3]李继锋,蔡建生,彭志坚,等.体外反搏治疗不稳定型心绞痛疗效观察[J].河北医学,2009,15(1):37-9.
[4]林琍.体外反搏治疗不稳定性心绞痛70例体会[J].数理医药学杂志,2009,22(6):682-3.
[5]米翔.增强型体外反搏治疗冠心病不稳定型心绞痛的临床观察[J].内科,2011,6(5):460.
[6]陈小卫,黄志文,田丽红,等.增强型体外反搏治疗冠心病不稳定型心绞痛疗效观察[J].中国实用医药,2011,6(5):17-8.
[7]黄浩.增强型体外反搏治疗不稳定性心绞痛150例临床观察[J].西部医学,2012,24(10):1983-4.
[8]李吉刚.增强型体外反搏联合药物治疗冠心病不稳定型心绞痛[J].实用医药杂志,2012,29(11):977-8.
[9]刘洪军,向睿.体外反搏治疗不稳定型心绞痛的临床疗效观察[J].中西医结合心脑血管病杂志,2013,11(11):1324-5.
[10]叶苑.体外反搏治疗冠心病不稳定型心绞痛的疗效分析[J].中国实用医药,2014,9(20):12-3.
[11]米翔,管起招,付鹏,等.体外反搏治疗冠心病不稳定型心绞痛的心电图效果观察[J].临床医学,2014,27(4):92-3.
[12]米翔,管起招,付鹏,等.增强型体外反搏仪治疗老年不稳定型心绞痛的临床研究[J].华夏医学,2015,28(1):32-5.
[13]高建军,孟艳玲.增强型体外反搏对不稳定型心绞痛患者心率变异性的影响[J].心理医生,2016,22(15):22-3.
[14]颜春菊.增强型体外反搏对不稳定型心绞痛患者血管内皮舒张功能及动脉弹性的影响[D].福建中医药大学,2016.
[15]伍贵富,杜志民,冷秀玉.增强型体外反搏的作用机制与常见问题[J].新医学,2008,39(3)144-7.
[16]Nichols WW,Estrada JC,Braith RW,et al.Enhanced external counterpulsation treatment improves arterial wall properties and wave reflection characteristics in patients with refractory angina[J].J Am Coll Cardiol,2006,48(6):1208-14.
[17]Barsheshet A,Hod H,Shechter M,et al.The effects of external counterpulsation therapy on circulating endothelial progenitor cells in patients with angina pectoris[J].Cardiology,2008,110(3):160-6.
[18]Casey DP,Conti CR,Nichols WW,et al.Effect of enhanced external counterpulsation on inflammatory cytokines and adhesion molecules in patients with angina pectoris and angiographic coronary artery disease[J].Am J Cardiol,2008,101(2):300-2.
[2]孟艳玲,高建军.增强型体外反搏对于冠心病不稳定型心绞痛患者心绞痛持续时间、硝酸甘油用量的影响[J].养生保健指南,2016(22):2.
[3]李继锋,蔡建生,彭志坚,等.体外反搏治疗不稳定型心绞痛疗效观察[J].河北医学,2009,15(1):37-9.
[4]林琍.体外反搏治疗不稳定性心绞痛70例体会[J].数理医药学杂志,2009,22(6):682-3.
[5]米翔.增强型体外反搏治疗冠心病不稳定型心绞痛的临床观察[J].内科,2011,6(5):460.
[6]陈小卫,黄志文,田丽红,等.增强型体外反搏治疗冠心病不稳定型心绞痛疗效观察[J].中国实用医药,2011,6(5):17-8.
[7]黄浩.增强型体外反搏治疗不稳定性心绞痛150例临床观察[J].西部医学,2012,24(10):1983-4.
[8]李吉刚.增强型体外反搏联合药物治疗冠心病不稳定型心绞痛[J].实用医药杂志,2012,29(11):977-8.
[9]刘洪军,向睿.体外反搏治疗不稳定型心绞痛的临床疗效观察[J].中西医结合心脑血管病杂志,2013,11(11):1324-5.
[10]叶苑.体外反搏治疗冠心病不稳定型心绞痛的疗效分析[J].中国实用医药,2014,9(20):12-3.
[11]米翔,管起招,付鹏,等.体外反搏治疗冠心病不稳定型心绞痛的心电图效果观察[J].临床医学,2014,27(4):92-3.
[12]米翔,管起招,付鹏,等.增强型体外反搏仪治疗老年不稳定型心绞痛的临床研究[J].华夏医学,2015,28(1):32-5.
[13]高建军,孟艳玲.增强型体外反搏对不稳定型心绞痛患者心率变异性的影响[J].心理医生,2016,22(15):22-3.
[14]颜春菊.增强型体外反搏对不稳定型心绞痛患者血管内皮舒张功能及动脉弹性的影响[D].福建中医药大学,2016.
[15]伍贵富,杜志民,冷秀玉.增强型体外反搏的作用机制与常见问题[J].新医学,2008,39(3)144-7.
[16]Nichols WW,Estrada JC,Braith RW,et al.Enhanced external counterpulsation treatment improves arterial wall properties and wave reflection characteristics in patients with refractory angina[J].J Am Coll Cardiol,2006,48(6):1208-14.
[17]Barsheshet A,Hod H,Shechter M,et al.The effects of external counterpulsation therapy on circulating endothelial progenitor cells in patients with angina pectoris[J].Cardiology,2008,110(3):160-6.
[18]Casey DP,Conti CR,Nichols WW,et al.Effect of enhanced external counterpulsation on inflammatory cytokines and adhesion molecules in patients with angina pectoris and angiographic coronary artery disease[J].Am J Cardiol,2008,101(2):300-2.