薄氏腹针联合中药周期法对排卵障碍性不孕患者生殖内分泌水平的影响
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摘要
目的:观察薄氏腹针联合中药周期法对排卵障碍性不孕患者生殖内分泌水平的影响。方法:将87例排卵障碍性不孕患者随机分为3组,针药组给予腹针+中药治疗,腹针组单独使用腹针治疗,西药组采用克罗米芬(CC)联合注射用绒促性素治疗,分别治疗3个月经周期。观察各组治疗前后基础卵泡刺激素(FSH)、黄体生成素(LH)、雌二醇(E_2)、泌乳素(PRL)、睾酮(T)及排卵期LH、E_2的变化,对比分析3组疗效。结果:针药组总有效率88.89%,腹针组总有效率92.59%,西药组总有效率56.6 7%。针药组及腹针组总有效率均高于西药组(P<0.05)。针药组及腹针组基础T水平治疗前后的差值均大于西药组,差异有统计学意义(P<0.016 7)。针药组及腹针组排卵期E_2水平治疗前后的差值均大于西药组,差异有统计学意义(P<0.016 7)。结论:薄氏腹针联合中药能改善排卵障碍性不孕患者的月经情况及临床症状,调节生殖内分泌,疗效优于西药治疗。
Objective:To observe the effect of Bo's abdominal acupuncture combined with Chinese medicine periodic therapy for reproductive endocrine level of patients with ovulation barrier sterile. Methods: Divided 87 cases of patients with ovulation barrier sterile into three groups randomly. The acupuncture and medication group was given abdominal acupuncture and Chinese medicine,and the abdominal acupuncture group was given abdominal acupuncture alone,and the western medicine group was given clomiphene citrate combined with chorionic gonadotropin by injection. The treatment for the three groups lasted for 3 menstrual cycles. Observed the changes of basic follicle-stimulating hormone(FSH), luteinizing hormone(LH), estradiol(E_2), prolactin(PRL), testosterone(T) and LH and E_2 in the ovulation period in each group before and after treatment. Compared and analyzed the curative effect in the three groups. Results:The total effective rate was 88.89% in the acupuncture and medication group, 92.59% in the abdomen acupuncture group, and 56.67% in the western medicine group. The difference means of the basic T levels before and after the treatment in the abdominal acupuncture group and the acupuncture and medication group were larger than that in the western medicine group,differences being significant(P < 0.016 7). The differences means of the levels of E_2 in the ovulation period before and after treatment in the acupuncture group and the acupuncture and medication group were larger than that in the western medicine group, differences being significant(P < 0.016 7). Conclusion:The application of Bo's abdominal acupuncture combined with Chinese medicine can improve the condition of menses and clinical symptoms of patients with ovulation barrier sterile and regulate their reproductive endocrine functions.Its curative effect is better than that of western medicine treatment.
Objective:To observe the effect of Bo's abdominal acupuncture combined with Chinese medicine periodic therapy for reproductive endocrine level of patients with ovulation barrier sterile. Methods: Divided 87 cases of patients with ovulation barrier sterile into three groups randomly. The acupuncture and medication group was given abdominal acupuncture and Chinese medicine,and the abdominal acupuncture group was given abdominal acupuncture alone,and the western medicine group was given clomiphene citrate combined with chorionic gonadotropin by injection. The treatment for the three groups lasted for 3 menstrual cycles. Observed the changes of basic follicle-stimulating hormone(FSH), luteinizing hormone(LH), estradiol(E_2), prolactin(PRL), testosterone(T) and LH and E_2 in the ovulation period in each group before and after treatment. Compared and analyzed the curative effect in the three groups. Results:The total effective rate was 88.89% in the acupuncture and medication group, 92.59% in the abdomen acupuncture group, and 56.67% in the western medicine group. The difference means of the basic T levels before and after the treatment in the abdominal acupuncture group and the acupuncture and medication group were larger than that in the western medicine group,differences being significant(P < 0.016 7). The differences means of the levels of E_2 in the ovulation period before and after treatment in the acupuncture group and the acupuncture and medication group were larger than that in the western medicine group, differences being significant(P < 0.016 7). Conclusion:The application of Bo's abdominal acupuncture combined with Chinese medicine can improve the condition of menses and clinical symptoms of patients with ovulation barrier sterile and regulate their reproductive endocrine functions.Its curative effect is better than that of western medicine treatment.
引文
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[2]华克勤.实用妇产科学[M].3版.北京:人民卫生出版社,2013:178.
[3]郑筱萸.中药新药临床研究指导原则(试行)[M].北京:中国医药科技出版社,2002.
[4]钟礼美,周楚华.中药和针刺排卵机制的研究[J].天津中医,1990(5):17.
[5]薄智云.腹针疗法[M].北京:中国中医药出版社,2012.