益生菌发酵中草药的特性及在动物生产中的应用
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摘要
益生菌发酵中草药是传统中草药经过微生物发酵技术处理,具有增强中草药的药性,促进中草药成分的转化,降低某些毒性成分的含量,以及益生菌和中草药的协调增效等作用。发酵中草药作为饲料添加剂应用于畜牧生产上已有很多研究。本文综述了发酵中草药的特性以及在动物生产上的应用现状,为发酵中草药的进一步研究和合理应用提供参考。
Probiotics fermented Chinese herbal medicine is traditional Chinese herbal medicine treated by microbial fermentation technology,the fermentation process can enhance pharmaceutical properties of Chinese herbal medicine,improve the transformation of its active components,reducing the content of some toxic components,and have synergistic effect between probiotics and Chinese herbal medicine. Many study have been reported about its application as feed additive in animal husbandry. This paper mainly reviewed the characteristics of fermented Chinese herbal medicine,as well as its application in animal production. So as to provide reference for the further study and reasonable utilization of fermented Chinese herbal medicine.
Probiotics fermented Chinese herbal medicine is traditional Chinese herbal medicine treated by microbial fermentation technology,the fermentation process can enhance pharmaceutical properties of Chinese herbal medicine,improve the transformation of its active components,reducing the content of some toxic components,and have synergistic effect between probiotics and Chinese herbal medicine. Many study have been reported about its application as feed additive in animal husbandry. This paper mainly reviewed the characteristics of fermented Chinese herbal medicine,as well as its application in animal production. So as to provide reference for the further study and reasonable utilization of fermented Chinese herbal medicine.
引文
[1]董睿方,王政,陈泠,等.RP-HPLC法测定沙棘叶发酵前后4种黄酮苷类成分含量的变化[J].药学实践杂志,2017,35(6):526~529.
[2]范作良,鞠雷,李汝春,等.中草药制剂发酵前后对蛋鸡生产性能及血清生化指标影响[J].山东畜牧兽医,2016,37(9):2~4.
[3]贾雪巍,董金香,于洋,等.灵芝菌液体发酵人参茎叶总皂苷化学成分变化及其抗肿瘤活性[J].吉林大学学报:医学版,2017,43(3):543~549+668.
[4]韩春杨,刘翠艳,牛钟相.中药制剂发酵前后成分的变化及对肉鸡部分免疫指标和生长的影响[J].畜牧兽医学报,2005,11:116~120.
[5]韩洁,王婷,张玉玲,等.肠菌群对吴茱萸体外代谢转化的作用[J].贵州农业科学,2011,39(7):112~115.
[6]江南,魏巍,许晓燕,等.中药川乌的固体发酵炮制新技术的建立[J].四川大学学报:自然科学版,2013,50(5):1104~1108.
[7]金尔光,陈洁,何斌,等.中草药超微粉在畜禽生产中的应用研究进展[J].中国兽药杂志,2015,49(9):60~64.
[8]李国红,沈月毛,王启方,等.发酵三七中的皂苷成分研究[J].中草药,2005,4:499~500.
[9]李国忠,刁新平.日粮中添加发酵黄芩对断奶仔猪生长性能的影响[J].中国饲料,2012,12:27~28+34.
[10]李汝,段振华,张红云,等.益生菌发酵中草药对育肥猪生长性能的影响[J].广西畜牧兽医,2018,34(5):244~246.
[11]刘春辉.固态发酵复方中药生产肉品质改良剂的研究[J].粮食与饲料工业,2012,5:53~56.
[12]刘观忠,安胜英,王凤霞.发酵中药对肉仔鸡生产性能和血液生化指标的影响[J].饲料工业,2011,32(23):47~49.
[13]刘学湘,潘扬,吴丽,等.基于固体发酵的白钱菌质急性毒性及镇痛作用的研究[J].中医药学报,2012,40(5):91~93.
[14]马东予.中草药饲料添加剂对母猪繁殖性能的影响[J].中兽医学杂志,2018,1:8~9.
[15]孟彬,孙敬锋,吕爱军.发酵中草药在水产养殖中的应用[J].水产科学,2018,37(3):421~426.
[16]孟维珊,崔毅,黄萌,等.中草药添加剂对降低鸡蛋胆固醇含量的研究[J].现代畜牧科技,2017,3:6~7.
[17]阮鸣.不同药(食)用真菌固体发酵对黄芪中黄芪甲苷的影响[J].中草药,2011,42(7):1421~1424.
[18]王彩玲,高树朋,杨宝生,等.虫草真菌发酵中草药对母猪繁殖性能的影响[J].养猪,2011,4:9~11.
[19]王身艳,刘学湘,王娟红,等.药用真菌双向固体发酵草乌后菌质对小鼠的急性毒性及致大鼠心律失常作用[J].安徽农业科学,2015,43(33):118~120+241.
[20]王晓芳,安永福,薛振卫,等.日粮中添加微量中药发酵制剂改善热应激下泌乳奶牛生产性能技术示范与推广效果[J].饲料研究,2016,12:26~28+33.
[21]吴道义,鲁立刚,张宗庆,等.中药微生态制剂对威宁黄牛杂交肉牛育肥效果和肉质的影响[J].饲料工业,2015,36(15):57~59.
[22]武洪志,宋玉卓,王志龙,等.发酵复方中草药对断奶仔猪生长性能、免疫和生化指标的影响[J].东北农业大学学报,2017,48(8):15~24.
[23]谢全喜,张建梅,于佳民,等.鼠李糖乳杆菌发酵中草药复合枯草芽孢杆菌对黄羽肉鸡生长后期免疫性能及大肠杆菌感染的研究[J].中国畜牧兽医,2016,43(6):1523~1529.
[24]张栋健,李薇,梁之桃,等.枳壳发酵炮制前后的成分变化及工艺优化[J].中国药房,2017,28(7):971~974.
[25]张敏,吴运莉,王鹏娇,等.淡豆豉药材发酵前后活性成分的变化研究[J].时珍国医国药,2015,26(2):363~364.
[26]赵晶.肠菌群转化对甘草主要成分及药效的影响:[硕士学位论文][D].贵阳:贵阳中医学院,2011.
[27]赵兴鑫,张振红,赵国先,等.中草药益生元对肉鸡肠道微生物和形态结构的影响[J].畜牧与兽医,2011,43(3):53~56.
[28]朱金凤,韩战强,肖杰,等.生物发酵中药对围产期母羊繁殖性能和羔羊健康的影响[J].农学学报,2014,4(10):88~90.
[29]Lee H S,Kim M R,Park Y,et al.Fermenting red ginseng enhances its safety and efficacy as a novel skin care anti-aging ingredient:In vitro and animal study[J].Journal of Medicinal Food,2012,15(11):1015~1023.
[30]Lee J H,Jin J S.Fermentation of traditional medicine:Present and future[J].Oriental Pharmacy and Experimental Medicine,2012,12(3):163~165.
[31]Mimaki Y,Yokosuka A,Kuroda M,et al.New bisdesmosidic triterpene from the roots of Pulsatilla chinensis[J].Journal of Natural Products,2001,64(9):1226~1229.
[32]Park H,Hwang Y H,Ma J Y.Acute toxicity and genotoxicity of fermented traditional medicine oyaksungi-san[J].Integrative Medicine Research,2017,6(2):214~222.
[33]Shan C H,Guo J J,Sun X S,et al.Effects of fermented Chinese herbal medicines on milk performance and immune function in latelactation cows under heat stress conditions[J].Journal of Animal Science,2018,96(10):4444~4457.
[34]Wang Y B,Xid Q H,Sun S,et al.Probiotics-fermented Massa Medicata Fermentata ameliorates weaning stress in piglets related to improving intestinal homeostasis[J].Applied Microbiology and Biotechnology,2018,102(24):10713~10727.
[35]W ang X,Xie H J,Liu F,et al.Production performance,immunity,and heat stress resistance in Jersey cattle fed a concentrate fermented with probiotics in the presence of a Chinese herbal combination[J].Animal Feed Science and Technology,2017,228:59~65.
[36]Xing Y,Cai L,Yin T P,et al.Improving the antioxidant activity and enriching salvianolic acids by the fermentation of Salvia miltiorrhizae with Geomyces luteus[J].Jouranl of Zhe Jiang University-Science B,2016,17(5):391~398.
[37]Zhai J F,Guo D X,Tlan H.Research and application of Chinese herbal feed additives in animal production[J].Pratacultural Science,2013,30:1131~1134.
[2]范作良,鞠雷,李汝春,等.中草药制剂发酵前后对蛋鸡生产性能及血清生化指标影响[J].山东畜牧兽医,2016,37(9):2~4.
[3]贾雪巍,董金香,于洋,等.灵芝菌液体发酵人参茎叶总皂苷化学成分变化及其抗肿瘤活性[J].吉林大学学报:医学版,2017,43(3):543~549+668.
[4]韩春杨,刘翠艳,牛钟相.中药制剂发酵前后成分的变化及对肉鸡部分免疫指标和生长的影响[J].畜牧兽医学报,2005,11:116~120.
[5]韩洁,王婷,张玉玲,等.肠菌群对吴茱萸体外代谢转化的作用[J].贵州农业科学,2011,39(7):112~115.
[6]江南,魏巍,许晓燕,等.中药川乌的固体发酵炮制新技术的建立[J].四川大学学报:自然科学版,2013,50(5):1104~1108.
[7]金尔光,陈洁,何斌,等.中草药超微粉在畜禽生产中的应用研究进展[J].中国兽药杂志,2015,49(9):60~64.
[8]李国红,沈月毛,王启方,等.发酵三七中的皂苷成分研究[J].中草药,2005,4:499~500.
[9]李国忠,刁新平.日粮中添加发酵黄芩对断奶仔猪生长性能的影响[J].中国饲料,2012,12:27~28+34.
[10]李汝,段振华,张红云,等.益生菌发酵中草药对育肥猪生长性能的影响[J].广西畜牧兽医,2018,34(5):244~246.
[11]刘春辉.固态发酵复方中药生产肉品质改良剂的研究[J].粮食与饲料工业,2012,5:53~56.
[12]刘观忠,安胜英,王凤霞.发酵中药对肉仔鸡生产性能和血液生化指标的影响[J].饲料工业,2011,32(23):47~49.
[13]刘学湘,潘扬,吴丽,等.基于固体发酵的白钱菌质急性毒性及镇痛作用的研究[J].中医药学报,2012,40(5):91~93.
[14]马东予.中草药饲料添加剂对母猪繁殖性能的影响[J].中兽医学杂志,2018,1:8~9.
[15]孟彬,孙敬锋,吕爱军.发酵中草药在水产养殖中的应用[J].水产科学,2018,37(3):421~426.
[16]孟维珊,崔毅,黄萌,等.中草药添加剂对降低鸡蛋胆固醇含量的研究[J].现代畜牧科技,2017,3:6~7.
[17]阮鸣.不同药(食)用真菌固体发酵对黄芪中黄芪甲苷的影响[J].中草药,2011,42(7):1421~1424.
[18]王彩玲,高树朋,杨宝生,等.虫草真菌发酵中草药对母猪繁殖性能的影响[J].养猪,2011,4:9~11.
[19]王身艳,刘学湘,王娟红,等.药用真菌双向固体发酵草乌后菌质对小鼠的急性毒性及致大鼠心律失常作用[J].安徽农业科学,2015,43(33):118~120+241.
[20]王晓芳,安永福,薛振卫,等.日粮中添加微量中药发酵制剂改善热应激下泌乳奶牛生产性能技术示范与推广效果[J].饲料研究,2016,12:26~28+33.
[21]吴道义,鲁立刚,张宗庆,等.中药微生态制剂对威宁黄牛杂交肉牛育肥效果和肉质的影响[J].饲料工业,2015,36(15):57~59.
[22]武洪志,宋玉卓,王志龙,等.发酵复方中草药对断奶仔猪生长性能、免疫和生化指标的影响[J].东北农业大学学报,2017,48(8):15~24.
[23]谢全喜,张建梅,于佳民,等.鼠李糖乳杆菌发酵中草药复合枯草芽孢杆菌对黄羽肉鸡生长后期免疫性能及大肠杆菌感染的研究[J].中国畜牧兽医,2016,43(6):1523~1529.
[24]张栋健,李薇,梁之桃,等.枳壳发酵炮制前后的成分变化及工艺优化[J].中国药房,2017,28(7):971~974.
[25]张敏,吴运莉,王鹏娇,等.淡豆豉药材发酵前后活性成分的变化研究[J].时珍国医国药,2015,26(2):363~364.
[26]赵晶.肠菌群转化对甘草主要成分及药效的影响:[硕士学位论文][D].贵阳:贵阳中医学院,2011.
[27]赵兴鑫,张振红,赵国先,等.中草药益生元对肉鸡肠道微生物和形态结构的影响[J].畜牧与兽医,2011,43(3):53~56.
[28]朱金凤,韩战强,肖杰,等.生物发酵中药对围产期母羊繁殖性能和羔羊健康的影响[J].农学学报,2014,4(10):88~90.
[29]Lee H S,Kim M R,Park Y,et al.Fermenting red ginseng enhances its safety and efficacy as a novel skin care anti-aging ingredient:In vitro and animal study[J].Journal of Medicinal Food,2012,15(11):1015~1023.
[30]Lee J H,Jin J S.Fermentation of traditional medicine:Present and future[J].Oriental Pharmacy and Experimental Medicine,2012,12(3):163~165.
[31]Mimaki Y,Yokosuka A,Kuroda M,et al.New bisdesmosidic triterpene from the roots of Pulsatilla chinensis[J].Journal of Natural Products,2001,64(9):1226~1229.
[32]Park H,Hwang Y H,Ma J Y.Acute toxicity and genotoxicity of fermented traditional medicine oyaksungi-san[J].Integrative Medicine Research,2017,6(2):214~222.
[33]Shan C H,Guo J J,Sun X S,et al.Effects of fermented Chinese herbal medicines on milk performance and immune function in latelactation cows under heat stress conditions[J].Journal of Animal Science,2018,96(10):4444~4457.
[34]Wang Y B,Xid Q H,Sun S,et al.Probiotics-fermented Massa Medicata Fermentata ameliorates weaning stress in piglets related to improving intestinal homeostasis[J].Applied Microbiology and Biotechnology,2018,102(24):10713~10727.
[35]W ang X,Xie H J,Liu F,et al.Production performance,immunity,and heat stress resistance in Jersey cattle fed a concentrate fermented with probiotics in the presence of a Chinese herbal combination[J].Animal Feed Science and Technology,2017,228:59~65.
[36]Xing Y,Cai L,Yin T P,et al.Improving the antioxidant activity and enriching salvianolic acids by the fermentation of Salvia miltiorrhizae with Geomyces luteus[J].Jouranl of Zhe Jiang University-Science B,2016,17(5):391~398.
[37]Zhai J F,Guo D X,Tlan H.Research and application of Chinese herbal feed additives in animal production[J].Pratacultural Science,2013,30:1131~1134.