中国蛙类疾病病原学研究进展
|
摘要
近年来由于市场需求增大,蛙类养殖在中国迅速发展,但因养殖密度过高、管理不当,蛙病流行造成了巨大经济损失。本文主要综述了病毒、细菌、真菌和寄生虫引起的蛙类疾病的病原学研究进展,详细介绍病原体种类、抗菌药物筛选、致病机理、疫苗制备等相关研究,为防治养殖蛙类主要疾病提供参考。
In recent years, frog farming has been rapidly developed in China with the increasing market demand, but many frog diseases bring huge economic losses for farmers due to high farming density, improper farming management and other factors. The etiology of frog diseases caused by bacterium, virus, fungus and parasite was reviewed in order to make scientific and technical workers and related technical personnel better understand the pathogenesis of frog disease. The type of pathogen, antibacterial drug screening,pathogenic mechanism and vaccine preparation were discussed in detail to provide a good reference for the prevention and control of frog diseases in China.
In recent years, frog farming has been rapidly developed in China with the increasing market demand, but many frog diseases bring huge economic losses for farmers due to high farming density, improper farming management and other factors. The etiology of frog diseases caused by bacterium, virus, fungus and parasite was reviewed in order to make scientific and technical workers and related technical personnel better understand the pathogenesis of frog disease. The type of pathogen, antibacterial drug screening,pathogenic mechanism and vaccine preparation were discussed in detail to provide a good reference for the prevention and control of frog diseases in China.
引文
[1]吴金雨.黑龙江省林蛙养殖业可持续发展研究[D].哈尔滨:东北农业大学,2014.
[2]肖克宇,黄志坚.牛蛙爱德华氏菌病病原菌的鉴定和致病因素的研究[J].水产学报,1997,21(3):316-321.
[3]陈晓凤,陈祈辉,王好镇,等.牛蛙“肝肿大病”病原的研究[J].集美大学学报:自然科学版,1995(2):32-37.
[4]舒新华,肖克宇,金燮理,等.牛蛙腐皮病致病细菌的初步研究[J].水产学报,1997(S1):71-76.
[5]叶雪平,杨广智.牛蛙脑膜炎(歪脖子病)病原分离及防治技术研究[J].浙江水产学院学报,1996,15(4):301-304.
[6]叶雪平,顾金华,杨广智,等.牛蛙温和气单胞菌病病原及防治[J].上海水产大学学报,2000,9(1):78-80.
[7]吴宝红,樊汶樵,姜玉松,等.金黄杆菌感染棘腹蛙的分离鉴定[J].中国兽医杂志,2015,51(12):97-99.
[8]廖冰洁,樊汶樵,周莉,等.一例棘腹蛙“白内障”的病原分离鉴定[J].湖北畜牧兽医,2014,35(8):8-11.
[9]Rigney M M,Zilinsky J W&Rouf M A.Pathogenicity of Aeromonas hydrophila in red leg disease in frogs[J].Current Microbiology,1978,1(3):175-179.
[10]胡成钰,洪一江.牛蛙红腿病病原菌敏感药物的筛选[J].水生态学杂志,2001,21(2):49.
[11]胡成钰,洪一江.牛蛙红腿病菌苗免疫试验[J].水生态学杂志,2001,21(1):38-39.
[12]丁燏,唐晓尘,简纪常,等.虎纹蛙烂趾病病原菌分离鉴定与药敏试验[J].水产科学,2009,28(2):67-70.
[13]张建平,肖向红,柴龙会.东北林蛙烂趾病病原菌的分离鉴定及药敏试验[J].黑龙江畜牧兽医,2014(2):93-95.
[14]贺路,艾晓辉.牛蛙腹水病病原研究[J].淡水渔业,1995,25(3):16-18.
[15]乔志刚,李用芳,张会永.美国青蛙腐皮病病原菌的分离鉴定和致病因素研究[J].水产科技情报,2000,27(2):70-72.
[16]陈爱平,江育林,钱冬,等.蛙脑膜炎败血金黄杆菌病[J].中国水产,2012(5):51-52.
[17]Xie Z Y,Zhou Y C,Wang S F,et al.First isolation and identification of Elizabethkingia meningoseptica from cultured tiger frog,Rana tigerina rugulosa.[J].Veterinary Microbiology,2009,138(1):140-144.
[18]周永灿,朱传华,陈国华,等.虎纹蛙白内障病病原的分离鉴定及其免疫防治[J].上海海洋大学学报,2001,10(1):16-21.
[19]王瑞君,熊筱娟.棘胸蛙烂皮病奇异变形杆菌的分离、鉴定及对药物敏感性研究[J].淡水渔业,2012,42(4):31-34.
[20]舒新华,金燮理.牛蛙腐皮病防治药物筛选研究[J].淡水渔业,1995,25(6):12-14.
[21]陈晓凤,陈祈辉,夏梅珠.牛蛙“白内障”病病原及防治的研究[J].福建水产,1995(2):13-18.
[22]于喆,肖克宇,钟蕾,等.牛蛙腹水病病原鉴定和药敏试验[J].淡水渔业,2013,43(1):50-54.
[23]叶雪平,罗毅志,施伟达,等.美国青蛙“抽搐症”病原及防治研究[J].淡水渔业,2005,35(5):48-50.
[24]樊汶樵,周莉,廖冰洁,等.感染棘腹蛙的腐败希瓦菌的分离与鉴定[J].黑龙江畜牧兽医,2015(15):166-168.
[25]郑卫军,宋婷婷,郑善坚,等.棘胸蛙出血病病原鉴定及药敏试验[J].华东森林经理2016(1):42-45.
[26]程晓云,郑芊芷,宋婷婷,等.棘胸蛙白内障病原鉴定及药敏试验[J].浙江农业科学,2016,57(7):1141-1143.
[27]李晓英,罗洁,杜孝田,等.棘腹蛙“水肿病”病原的分离鉴定[J].动物医学进展,2016,37(8):116-119.
[28]龚艳清,陈信忠.牛蛙感染迟缓爱德华氏菌的研究[J].福建水产,2002(2):61-65.
[29]陈言峰,邹记兴.20种中草药对迟缓爱德华氏菌的体外抑菌试验[J].水生态学杂志,2011,32(5):110-113.
[30]陈晓凤,周常义,陈梦麟.牛蛙链球菌感染症病原的研究[J].集美大学学报:自然科学版,1999(2):45-50.
[31]陈超然,孟长明,陈昌福.二氧化氯与氨苄青霉素结合使用对牛蛙链球菌症的疗效[J].淡水渔业,2002,32(2):43-45.
[32]周冬仁,陈莎莎,杭小英,等.牛蛙源无乳链球菌全菌疫苗免疫效果研究[J].中国农学通报,2012,28(14):135-137.
[33]郭秀平,林明辉,何有根,等.虎纹蛙蝌蚪致病菌株鉴定及药物敏感性分析[J].广东农业科学,2012,39(9):114-115.
[34]杨春浩.牛蛙歪头病病原、病理及敏感药物研究[D].长沙:湖南农业大学,2010.
[35]朱泉娣,李友康.牛蛙蝌蚪真菌性疾病——肤霉病的初步观察及防治报告[J].动物学杂志,1964(5):231-232,226.
[36]魏营.黑龙江省东北林蛙壶菌病调查及壶菌病风险评估指标体系研究[D].哈尔滨:东北林业大学,2010.
[37]Berger L,Speare R,Daszak P,et al.Chytridiomycosis causes amphibian mortality associated with population declines in the rain forests of Australia and Central America[J].Proceedings of the National Academy of Sciences,1998,95(15):9031-9036.
[38]Bradley G A,Rosen P C,Sredl M J,et al.Chytridiomycosis in native Arizona frogs[J].Journal of wildlife diseases,2002,38(1):206-212.
[39]Racaniello V R.Emerging infectious diseases[J].Journal of Clinical Investigation,2004,113(6):796.
[40]Nichols D K,Lamirande E W,Pessier A P,et al.Experimental transmission of cutaneous chytridiomycosis in dendrobatid frogs[J].Journal of Wildlife Diseases,2001,37(1):1-11.
[41]李莉娟,罗杨志,顾泽茂,等.蛙病毒3介导棘胸蛙的暴发性死亡[A].中国水产学会鱼病专业委员会2013年学术研讨会论文摘要汇编,2013.
[42]汪环,王思睿,王晓龙.东北林蛙种蛙蛙病毒LAMP快速检测[J].野生动物学报,2014,35(4):456-459.
[43]Miller D L,Rajeev S,Gray M J,et al.Frog virus 3 infection,cultured American bullfrogs[J].Emerging Infectious Diseases,2007,13(2):342-343.
[44]Brunner J L,Richards K&Collins J P.Dose and host characteristics influence virulence of Ranavirus Infections[J].Oecologia,2005,144(3):399-406.
[45]Hoverman J T,Gray M J&Miller D L.Anuran susceptibilities to Ranavirus:role of species identity,exposure route,and a novel virus isolate.[J].Diseases of Aquatic Organisms,2010,89(2):97-107.
[46]王涵.我国不同地区曼氏迭宫绦虫裂头蚴分离株的遗传多态性研究[D].郑州:郑州大学,2016.
[47]蔺西萌,刘长军,颜秋叶,等.生食蝌蚪感染曼氏裂头蚴发病的发现与调查[J].中国人兽共患病学报,2008,24(12):1173-1175.
[48]叶雪平.蛙病的诊断与防治技术[J].水产科技情报,1999,26(2):82-83.
[49]龚迎春,余育和.车轮虫分类与系统发育研究进展[J].动物学研究,2007,28(2):217-224.
[50]王战勇,李宁,苏婷婷.中国林蛙皮抗菌肽的提取纯化及抑菌活性检测[J].食品科学,2010(3):132-135.
[51]Tennessen J A,Woodhams D C,Chaurand P,et al.Variations in the expressed antimicrobial peptide repertoire of northern leopard frog(Rana pipiens)populations suggest intraspecies differences in resistance to pathogens[J].Developmental&Comparative Immunology,2009,33(12):1247-1257.
[52]Schadich E.Skin peptide activities against opportunistic bacterial pathogens of the African cawed frog(Xenopus laevis)and three litoria frogs[J].Journal of Herpetology,2009,43(2):173-183.
[53]Schadich E&Cole A L J.Pathogenicity of Aeromonas hydrophila,Klebsiella pneumoniae,and Proteus mirabilis to brown tree frogs(Litoria ewingii).[J].Comparative Medicine,2010,60(2):114-117.
[54]李明,宋婷婷,郑荣泉,等.棘胸蛙歪头病病原分离、鉴定与药敏试验[J].安徽农业科学,2016(3):64-66.
[55]马有智,卢媛媛,何琳,等.棘胸蛙嗜水气单胞菌卵黄抗体的制备及其保护作用研究[J].黑龙江畜牧兽医,2013(9):142-143.
[56]赵明军,张洪玉,周状.中草药对水产动物疾病防治的药效学研究综述[J].安徽农业科学,2009,37(36):18010-18015,18036.
[2]肖克宇,黄志坚.牛蛙爱德华氏菌病病原菌的鉴定和致病因素的研究[J].水产学报,1997,21(3):316-321.
[3]陈晓凤,陈祈辉,王好镇,等.牛蛙“肝肿大病”病原的研究[J].集美大学学报:自然科学版,1995(2):32-37.
[4]舒新华,肖克宇,金燮理,等.牛蛙腐皮病致病细菌的初步研究[J].水产学报,1997(S1):71-76.
[5]叶雪平,杨广智.牛蛙脑膜炎(歪脖子病)病原分离及防治技术研究[J].浙江水产学院学报,1996,15(4):301-304.
[6]叶雪平,顾金华,杨广智,等.牛蛙温和气单胞菌病病原及防治[J].上海水产大学学报,2000,9(1):78-80.
[7]吴宝红,樊汶樵,姜玉松,等.金黄杆菌感染棘腹蛙的分离鉴定[J].中国兽医杂志,2015,51(12):97-99.
[8]廖冰洁,樊汶樵,周莉,等.一例棘腹蛙“白内障”的病原分离鉴定[J].湖北畜牧兽医,2014,35(8):8-11.
[9]Rigney M M,Zilinsky J W&Rouf M A.Pathogenicity of Aeromonas hydrophila in red leg disease in frogs[J].Current Microbiology,1978,1(3):175-179.
[10]胡成钰,洪一江.牛蛙红腿病病原菌敏感药物的筛选[J].水生态学杂志,2001,21(2):49.
[11]胡成钰,洪一江.牛蛙红腿病菌苗免疫试验[J].水生态学杂志,2001,21(1):38-39.
[12]丁燏,唐晓尘,简纪常,等.虎纹蛙烂趾病病原菌分离鉴定与药敏试验[J].水产科学,2009,28(2):67-70.
[13]张建平,肖向红,柴龙会.东北林蛙烂趾病病原菌的分离鉴定及药敏试验[J].黑龙江畜牧兽医,2014(2):93-95.
[14]贺路,艾晓辉.牛蛙腹水病病原研究[J].淡水渔业,1995,25(3):16-18.
[15]乔志刚,李用芳,张会永.美国青蛙腐皮病病原菌的分离鉴定和致病因素研究[J].水产科技情报,2000,27(2):70-72.
[16]陈爱平,江育林,钱冬,等.蛙脑膜炎败血金黄杆菌病[J].中国水产,2012(5):51-52.
[17]Xie Z Y,Zhou Y C,Wang S F,et al.First isolation and identification of Elizabethkingia meningoseptica from cultured tiger frog,Rana tigerina rugulosa.[J].Veterinary Microbiology,2009,138(1):140-144.
[18]周永灿,朱传华,陈国华,等.虎纹蛙白内障病病原的分离鉴定及其免疫防治[J].上海海洋大学学报,2001,10(1):16-21.
[19]王瑞君,熊筱娟.棘胸蛙烂皮病奇异变形杆菌的分离、鉴定及对药物敏感性研究[J].淡水渔业,2012,42(4):31-34.
[20]舒新华,金燮理.牛蛙腐皮病防治药物筛选研究[J].淡水渔业,1995,25(6):12-14.
[21]陈晓凤,陈祈辉,夏梅珠.牛蛙“白内障”病病原及防治的研究[J].福建水产,1995(2):13-18.
[22]于喆,肖克宇,钟蕾,等.牛蛙腹水病病原鉴定和药敏试验[J].淡水渔业,2013,43(1):50-54.
[23]叶雪平,罗毅志,施伟达,等.美国青蛙“抽搐症”病原及防治研究[J].淡水渔业,2005,35(5):48-50.
[24]樊汶樵,周莉,廖冰洁,等.感染棘腹蛙的腐败希瓦菌的分离与鉴定[J].黑龙江畜牧兽医,2015(15):166-168.
[25]郑卫军,宋婷婷,郑善坚,等.棘胸蛙出血病病原鉴定及药敏试验[J].华东森林经理2016(1):42-45.
[26]程晓云,郑芊芷,宋婷婷,等.棘胸蛙白内障病原鉴定及药敏试验[J].浙江农业科学,2016,57(7):1141-1143.
[27]李晓英,罗洁,杜孝田,等.棘腹蛙“水肿病”病原的分离鉴定[J].动物医学进展,2016,37(8):116-119.
[28]龚艳清,陈信忠.牛蛙感染迟缓爱德华氏菌的研究[J].福建水产,2002(2):61-65.
[29]陈言峰,邹记兴.20种中草药对迟缓爱德华氏菌的体外抑菌试验[J].水生态学杂志,2011,32(5):110-113.
[30]陈晓凤,周常义,陈梦麟.牛蛙链球菌感染症病原的研究[J].集美大学学报:自然科学版,1999(2):45-50.
[31]陈超然,孟长明,陈昌福.二氧化氯与氨苄青霉素结合使用对牛蛙链球菌症的疗效[J].淡水渔业,2002,32(2):43-45.
[32]周冬仁,陈莎莎,杭小英,等.牛蛙源无乳链球菌全菌疫苗免疫效果研究[J].中国农学通报,2012,28(14):135-137.
[33]郭秀平,林明辉,何有根,等.虎纹蛙蝌蚪致病菌株鉴定及药物敏感性分析[J].广东农业科学,2012,39(9):114-115.
[34]杨春浩.牛蛙歪头病病原、病理及敏感药物研究[D].长沙:湖南农业大学,2010.
[35]朱泉娣,李友康.牛蛙蝌蚪真菌性疾病——肤霉病的初步观察及防治报告[J].动物学杂志,1964(5):231-232,226.
[36]魏营.黑龙江省东北林蛙壶菌病调查及壶菌病风险评估指标体系研究[D].哈尔滨:东北林业大学,2010.
[37]Berger L,Speare R,Daszak P,et al.Chytridiomycosis causes amphibian mortality associated with population declines in the rain forests of Australia and Central America[J].Proceedings of the National Academy of Sciences,1998,95(15):9031-9036.
[38]Bradley G A,Rosen P C,Sredl M J,et al.Chytridiomycosis in native Arizona frogs[J].Journal of wildlife diseases,2002,38(1):206-212.
[39]Racaniello V R.Emerging infectious diseases[J].Journal of Clinical Investigation,2004,113(6):796.
[40]Nichols D K,Lamirande E W,Pessier A P,et al.Experimental transmission of cutaneous chytridiomycosis in dendrobatid frogs[J].Journal of Wildlife Diseases,2001,37(1):1-11.
[41]李莉娟,罗杨志,顾泽茂,等.蛙病毒3介导棘胸蛙的暴发性死亡[A].中国水产学会鱼病专业委员会2013年学术研讨会论文摘要汇编,2013.
[42]汪环,王思睿,王晓龙.东北林蛙种蛙蛙病毒LAMP快速检测[J].野生动物学报,2014,35(4):456-459.
[43]Miller D L,Rajeev S,Gray M J,et al.Frog virus 3 infection,cultured American bullfrogs[J].Emerging Infectious Diseases,2007,13(2):342-343.
[44]Brunner J L,Richards K&Collins J P.Dose and host characteristics influence virulence of Ranavirus Infections[J].Oecologia,2005,144(3):399-406.
[45]Hoverman J T,Gray M J&Miller D L.Anuran susceptibilities to Ranavirus:role of species identity,exposure route,and a novel virus isolate.[J].Diseases of Aquatic Organisms,2010,89(2):97-107.
[46]王涵.我国不同地区曼氏迭宫绦虫裂头蚴分离株的遗传多态性研究[D].郑州:郑州大学,2016.
[47]蔺西萌,刘长军,颜秋叶,等.生食蝌蚪感染曼氏裂头蚴发病的发现与调查[J].中国人兽共患病学报,2008,24(12):1173-1175.
[48]叶雪平.蛙病的诊断与防治技术[J].水产科技情报,1999,26(2):82-83.
[49]龚迎春,余育和.车轮虫分类与系统发育研究进展[J].动物学研究,2007,28(2):217-224.
[50]王战勇,李宁,苏婷婷.中国林蛙皮抗菌肽的提取纯化及抑菌活性检测[J].食品科学,2010(3):132-135.
[51]Tennessen J A,Woodhams D C,Chaurand P,et al.Variations in the expressed antimicrobial peptide repertoire of northern leopard frog(Rana pipiens)populations suggest intraspecies differences in resistance to pathogens[J].Developmental&Comparative Immunology,2009,33(12):1247-1257.
[52]Schadich E.Skin peptide activities against opportunistic bacterial pathogens of the African cawed frog(Xenopus laevis)and three litoria frogs[J].Journal of Herpetology,2009,43(2):173-183.
[53]Schadich E&Cole A L J.Pathogenicity of Aeromonas hydrophila,Klebsiella pneumoniae,and Proteus mirabilis to brown tree frogs(Litoria ewingii).[J].Comparative Medicine,2010,60(2):114-117.
[54]李明,宋婷婷,郑荣泉,等.棘胸蛙歪头病病原分离、鉴定与药敏试验[J].安徽农业科学,2016(3):64-66.
[55]马有智,卢媛媛,何琳,等.棘胸蛙嗜水气单胞菌卵黄抗体的制备及其保护作用研究[J].黑龙江畜牧兽医,2013(9):142-143.
[56]赵明军,张洪玉,周状.中草药对水产动物疾病防治的药效学研究综述[J].安徽农业科学,2009,37(36):18010-18015,18036.