成组生物毒性测试法在水质生物安全性评价中的应用
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摘要
近年来水体污染日益加剧,水质安全受到了人们的严重关注.相比传统水质检测指标,生物毒性测试利用受试物某些特定指标的变化,更直观地反映污染物对生态环境和人类健康造成的潜在性影响.不同生物对有毒污染物具有不同的致毒机理和反应敏感度,将多种生物毒性测试组合应用,发展成组生物毒性测试方法,完整地反映水体中所有共存污染物的综合生物毒性特征,更有效地评价水体的生物安全性.本文基于成组生物毒性测试法总结了无脊椎动物、藻类和细菌等受试生物,对比分析了由不同急性毒性试验、慢性毒性试验、致畸致突变试验等组成的测试方法,综述了潜在生物毒性效应指数法、毒性单位分级评价法、水质安全分级法和综合生物标志物响应指数法等评价方法及其在不同水体中的应用研究进展,为成组生物毒性测试法在水质生物安全性评价中的应用提供基础信息.
During last past years,water pollution was increasingly deterioted.So far,much attention has been paid to the water quality safety.The biological toxicity tests have become a promising means for the water quality monitoring,since it can intuitively reflect the potential influence of pollutants on ecological environment and human health through the biological toxicity index.Different organisms have different toxic mechanism and responding sensitivity for toxic pollutants.Developing biological toxicity test battery can effectively reflect the integrated biological toxicity of all pollutants and evaluate the ecological risk and environmental health effect.The testing organisms such as invertebrates,algae and bacteria were summarized;the testing methods such as acute and chronic toxicity test,teratogenic and mutagenicity test were comparative analyzed;the evaluation methods and their application in different water bodies such as Potential Ecotoxic Effects Probe,Toxicity Unit Classification System,Water Quality Safety Classification Evaluation and Integrated Biological Responses Method were summarized.This work provides the foundation for the application of biological toxicity test battery in water quality biological safety evaluation.
During last past years,water pollution was increasingly deterioted.So far,much attention has been paid to the water quality safety.The biological toxicity tests have become a promising means for the water quality monitoring,since it can intuitively reflect the potential influence of pollutants on ecological environment and human health through the biological toxicity index.Different organisms have different toxic mechanism and responding sensitivity for toxic pollutants.Developing biological toxicity test battery can effectively reflect the integrated biological toxicity of all pollutants and evaluate the ecological risk and environmental health effect.The testing organisms such as invertebrates,algae and bacteria were summarized;the testing methods such as acute and chronic toxicity test,teratogenic and mutagenicity test were comparative analyzed;the evaluation methods and their application in different water bodies such as Potential Ecotoxic Effects Probe,Toxicity Unit Classification System,Water Quality Safety Classification Evaluation and Integrated Biological Responses Method were summarized.This work provides the foundation for the application of biological toxicity test battery in water quality biological safety evaluation.
引文
[1]Zhou Rongbing,Zhu Lizhong,Yang Kun,et al.Distribution of organochlorine pesticides in surface water and sediments from Qiantang River,East China[J].Journal of Hazardous Materials,2006,137(1):68-75.
[2]Zhao Long,Hou Hong,Zhou Youya,et al.Distribution and ecological risk of polychlorinated biphenyls and organochlorine pesticides in surficial sediments from Haihe River and Haihe Estuary Area,China[J].Chemosphere,2010,78(10):1285-1293.
[3]Zhao Jianliang,Ying Guangguo,Liu Yousheng,et al.Occurrence and a screening-level risk assessment of human pharmaceuticals in the pearl river system,South China[J].Environmental Toxicology and Chemistry,2010,29(6):1377-1384.
[4]FIsher D J,Knott M H,Turley B S,et al.Acute and chronic toxicity of industrial and municipal effluents in Maryland[J].Water Environment Research,1998,70(1):101-107.
[5]Kenaga E E.Test organisms and methods useful for early assessment of acute toxicity of chemicals[J].Environmental Science and Technology,1978,12(12):1322-1339.
[6]骆坚平,马梅,王子健,等.用成组生物毒性测试方法评价北方某市饮用水安全性[J].给水排水,2006(8):17-21.
[7]Li K J,He W H,Hu Q,et al.Ecological restoration of reclaimed wastewater lakes using submerged plants and zooplankton[J].Water and Environment Journal,2014,28(3):323-328.
[8]Ren Shijin,Frymier Paul D.Use of multidimensional scaling in the selection of wastewater toxicity test battery components[J].Water Research,2003,37(7):1655-1661.
[9]Juvonen R,Martikainen E,Schultz E,et al.A battery of toxicity tests as indicators of decontamination in composting oily waste[J].Ecotoxicology and Environmental Safety,2000,47(2):156-166.
[10]余若祯,穆玉峰,王海燕,等.排水综合评价中的生物毒性测试技术[J].环境科学研究,2014(4):390-397.
[11]Blaise Christian.Overview of contemporary toxicity testing[M].Rard Jean-Fran Ois:Small-scale Freshwater Toxicity Investigations.Springer Netherlands,2005:1-68.
[12]李雪梅,黎艳,杨建,等.采用斑马鱼评估地下回灌再生水的生物安全性[J].中国给水排水,2014(11):77-80.
[13]伍辛泷,黄乾生,方超,等.新兴海洋生态毒理学模式生物---海洋青鳉鱼(Oryzias melastigma)[J].生态毒理学报,2012(4):345-353.
[14]张彩明,陈应华,吴常文,等.Cr~(6+)对日本黄姑鱼(Nibea japonica)外周血细胞及抗氧化酶(SOD、CAT)活性的影响[J].海洋与湖沼,2013(2):332-336.
[15]Villegas-Navarro A,Santiago M,Rodr Guez,et al.Determination of LC50from Daphnia magna in treated industrial waste waters and non-treated hospital effluents[J].Environment International,1997,23(4):535-540.
[16]徐吉洋,张文萍,李少南,等.萼花臂尾轮虫毒性试验的方法学研究[J].生态毒理学报,2015,(2):346-352.
[17]Mankiewicz-Boczek J,Na覥ecz-Jawecki G,Drobniewska A,et al.Application of a microbiotests battery for complete toxicity assessment of rivers[J].Ecotoxicology and Environmental Safety,2008,71(3):830-836.
[18]Chen Hui,Chen Jie,Guo Yanan,et al.Evaluation of the role of the glutathione redox cycle in Cu(II)toxicity to green algae by a chiral perturbation approach[J].Aquatic Toxicology,2012,120-121:19-26.
[19]Phillips,David H Arlt,Volker M.Molecular.Clinical and environmental toxicology[M].Basel;Birkh覿user Basel,2009:289-323.
[20]林朝晖.Ames试验在水质检测方面的应用[J].微生物学通报,2002(3):66-70.
[21]HAmer Bojan,Bihari Nevenka,Reifferscheid Georg,et al Evaluation of the SOS/umu-test post-treatment assay for the detection of genotoxic activities of pure compounds and complex environmental mixtures[J].Mutation Research/Genetic Toxicology and Environmental Mutagenesis,2000,466(2):161-171.
[22]Ventura S Nia P M,Gon Alves Ana M M,Gon Alves Fernando,et al.Assessing the toxicity on[C3mim][Tf2N]to aquatic organisms of different trophic levels[J].Aquatic Toxicology,2010,96(4):290-297.
[23]Monarca Silvano,Zani Claudia,Richardson Susan D,et al.A new approach to evaluating the toxicity and genotoxicity of disinfected drinking water[J].Water Research,2004,38(17):3809-3819.
[24]张俊然,朱惠刚.遗传毒理学短期测试方法的发展及在检测饮用水方面的应用[J].上海环境科学,1996(2):38-41.
[25]言野,李娜,刘楠楠,等.利用改进的SOS/umu方法检测水处理过程中污染物的遗传毒性效应[J].生态毒理学报,2013(6):909-916.
[26]Tang Xin,Wu Qianyuan,Yang Yang,et al.Genotoxicity removal of reclaimed water during ozonation[J].Journal o Environmental Sciences,2014,26(6):1243-1248.
[27]刘瑞祥,齐永平,吕敏.蚕豆根尖细胞微核技术检测合成氨工业水的遗传毒性[J].生物技术,2007(1):58-60.
[28]贺磊,刘智峰.蚕豆根尖微核试验在水环境污染物检测中的应用[J].广东农业科学,2011(1):171-173.
[29]陈颖,王磊,王子健.用彗星实验技术检测环境遗传毒性物质[J].土壤学报,2006(4):673-678.
[30]邢彩虹,李桂兰,尹松年.单细胞凝胶电泳技术及其应用进展[J].卫生研究,2004(5):638-640.
[31]Monarca Silvano,Feretti Donatella,Collivignarelli Carlo,et al.The influence of different disinfectants on mutagenicity and toxicity of urban wastewater[J].Water Research,2000,34(17):4261-4269.
[32]Xu Jianying,Zhao Chuntao,Wei Dongbin,et al.A toxicity-based method for evaluating safety of reclaimed water for environmental reuses[J].J Environ Sci(China),2014,26(10):1961-1969.
[33]邹叶娜,蔡焕兴,薛银刚,等.成组生物毒性测试法综合评价典型工业废水毒性[J].生态毒理学报,2012(4):381-388.
[34]孙晓怡,王毓军,巩宗强,等.抚顺市工业废水生物毒性评价[J].生态学杂志,2006(5):546-549.
[35]Costan G,Bermingham N,Blaise C,et al.Potential ecotoxic effects probe(PEEP):A novel index to assess and compare the toxic potential of industrial effluents[J].Environmental Toxicology and Water Quality,1993,8(2):115-140.
[36]Persoone Guido,Marsalek Blahoslav,Blinova Irina,et al.A practical and user-friendly toxicity classification system with microbiotests for natural waters and wastewaters[J].Environmental Toxicology,2003,18(6):395-402.
[37]Wei Dongbin,Tan Zhuowei,Du Yuguo.Toxicity-based assessment of the treatment performance of wastewater treatment and reclamation processes[J].J Environ Sci(China),2012,24(6):969-978.
[38]孟范平,杨菲菲,程凤莲.基于生物标志物指数法的海洋环境评价方法综述[J].应用生态学报,2012(4):1128-1136.
[39]Sanchez Wilfried,Burgeot Thierry,Porcher Jean-Marc.Anovel“Integrated Biomarker Response”calculation based on reference deviation concept[J].Environmental Science and Pollution Research,2012,20(5):2721-2725.
[40]Beliaeff Benoit,Burgeot Thierry.Integrated biomarker response:A useful tool for ecological risk asse-ssment[J].Environmental Toxicology and Chemistry,2002,21(6):1316-1322.
[41]曹宇.农药工业废水的生物毒性评价研究[D].西安:长安大学,2015.
[42]Hafner Christoph,Gartiser Stefan,Garcia-K Ufer Manuel,et al.Investigations on sediment toxicity of German rivers applying a standardized bioassay battery[J].Environmental Science and Pollution Research,2015,22(21):16358-16370.
[43]Jia Ai,Escher Beate I,Leusch Frederic D L,et al.In vitro bioassays to evaluate complex chemical mixtures in recycled water[J].Water Research,2015,801-811.
[44]苏磊.基于海洋倾倒目的之污水污泥化学分析及生物毒性研究[D].上海:上海海洋大学,2015.
[2]Zhao Long,Hou Hong,Zhou Youya,et al.Distribution and ecological risk of polychlorinated biphenyls and organochlorine pesticides in surficial sediments from Haihe River and Haihe Estuary Area,China[J].Chemosphere,2010,78(10):1285-1293.
[3]Zhao Jianliang,Ying Guangguo,Liu Yousheng,et al.Occurrence and a screening-level risk assessment of human pharmaceuticals in the pearl river system,South China[J].Environmental Toxicology and Chemistry,2010,29(6):1377-1384.
[4]FIsher D J,Knott M H,Turley B S,et al.Acute and chronic toxicity of industrial and municipal effluents in Maryland[J].Water Environment Research,1998,70(1):101-107.
[5]Kenaga E E.Test organisms and methods useful for early assessment of acute toxicity of chemicals[J].Environmental Science and Technology,1978,12(12):1322-1339.
[6]骆坚平,马梅,王子健,等.用成组生物毒性测试方法评价北方某市饮用水安全性[J].给水排水,2006(8):17-21.
[7]Li K J,He W H,Hu Q,et al.Ecological restoration of reclaimed wastewater lakes using submerged plants and zooplankton[J].Water and Environment Journal,2014,28(3):323-328.
[8]Ren Shijin,Frymier Paul D.Use of multidimensional scaling in the selection of wastewater toxicity test battery components[J].Water Research,2003,37(7):1655-1661.
[9]Juvonen R,Martikainen E,Schultz E,et al.A battery of toxicity tests as indicators of decontamination in composting oily waste[J].Ecotoxicology and Environmental Safety,2000,47(2):156-166.
[10]余若祯,穆玉峰,王海燕,等.排水综合评价中的生物毒性测试技术[J].环境科学研究,2014(4):390-397.
[11]Blaise Christian.Overview of contemporary toxicity testing[M].Rard Jean-Fran Ois:Small-scale Freshwater Toxicity Investigations.Springer Netherlands,2005:1-68.
[12]李雪梅,黎艳,杨建,等.采用斑马鱼评估地下回灌再生水的生物安全性[J].中国给水排水,2014(11):77-80.
[13]伍辛泷,黄乾生,方超,等.新兴海洋生态毒理学模式生物---海洋青鳉鱼(Oryzias melastigma)[J].生态毒理学报,2012(4):345-353.
[14]张彩明,陈应华,吴常文,等.Cr~(6+)对日本黄姑鱼(Nibea japonica)外周血细胞及抗氧化酶(SOD、CAT)活性的影响[J].海洋与湖沼,2013(2):332-336.
[15]Villegas-Navarro A,Santiago M,Rodr Guez,et al.Determination of LC50from Daphnia magna in treated industrial waste waters and non-treated hospital effluents[J].Environment International,1997,23(4):535-540.
[16]徐吉洋,张文萍,李少南,等.萼花臂尾轮虫毒性试验的方法学研究[J].生态毒理学报,2015,(2):346-352.
[17]Mankiewicz-Boczek J,Na覥ecz-Jawecki G,Drobniewska A,et al.Application of a microbiotests battery for complete toxicity assessment of rivers[J].Ecotoxicology and Environmental Safety,2008,71(3):830-836.
[18]Chen Hui,Chen Jie,Guo Yanan,et al.Evaluation of the role of the glutathione redox cycle in Cu(II)toxicity to green algae by a chiral perturbation approach[J].Aquatic Toxicology,2012,120-121:19-26.
[19]Phillips,David H Arlt,Volker M.Molecular.Clinical and environmental toxicology[M].Basel;Birkh覿user Basel,2009:289-323.
[20]林朝晖.Ames试验在水质检测方面的应用[J].微生物学通报,2002(3):66-70.
[21]HAmer Bojan,Bihari Nevenka,Reifferscheid Georg,et al Evaluation of the SOS/umu-test post-treatment assay for the detection of genotoxic activities of pure compounds and complex environmental mixtures[J].Mutation Research/Genetic Toxicology and Environmental Mutagenesis,2000,466(2):161-171.
[22]Ventura S Nia P M,Gon Alves Ana M M,Gon Alves Fernando,et al.Assessing the toxicity on[C3mim][Tf2N]to aquatic organisms of different trophic levels[J].Aquatic Toxicology,2010,96(4):290-297.
[23]Monarca Silvano,Zani Claudia,Richardson Susan D,et al.A new approach to evaluating the toxicity and genotoxicity of disinfected drinking water[J].Water Research,2004,38(17):3809-3819.
[24]张俊然,朱惠刚.遗传毒理学短期测试方法的发展及在检测饮用水方面的应用[J].上海环境科学,1996(2):38-41.
[25]言野,李娜,刘楠楠,等.利用改进的SOS/umu方法检测水处理过程中污染物的遗传毒性效应[J].生态毒理学报,2013(6):909-916.
[26]Tang Xin,Wu Qianyuan,Yang Yang,et al.Genotoxicity removal of reclaimed water during ozonation[J].Journal o Environmental Sciences,2014,26(6):1243-1248.
[27]刘瑞祥,齐永平,吕敏.蚕豆根尖细胞微核技术检测合成氨工业水的遗传毒性[J].生物技术,2007(1):58-60.
[28]贺磊,刘智峰.蚕豆根尖微核试验在水环境污染物检测中的应用[J].广东农业科学,2011(1):171-173.
[29]陈颖,王磊,王子健.用彗星实验技术检测环境遗传毒性物质[J].土壤学报,2006(4):673-678.
[30]邢彩虹,李桂兰,尹松年.单细胞凝胶电泳技术及其应用进展[J].卫生研究,2004(5):638-640.
[31]Monarca Silvano,Feretti Donatella,Collivignarelli Carlo,et al.The influence of different disinfectants on mutagenicity and toxicity of urban wastewater[J].Water Research,2000,34(17):4261-4269.
[32]Xu Jianying,Zhao Chuntao,Wei Dongbin,et al.A toxicity-based method for evaluating safety of reclaimed water for environmental reuses[J].J Environ Sci(China),2014,26(10):1961-1969.
[33]邹叶娜,蔡焕兴,薛银刚,等.成组生物毒性测试法综合评价典型工业废水毒性[J].生态毒理学报,2012(4):381-388.
[34]孙晓怡,王毓军,巩宗强,等.抚顺市工业废水生物毒性评价[J].生态学杂志,2006(5):546-549.
[35]Costan G,Bermingham N,Blaise C,et al.Potential ecotoxic effects probe(PEEP):A novel index to assess and compare the toxic potential of industrial effluents[J].Environmental Toxicology and Water Quality,1993,8(2):115-140.
[36]Persoone Guido,Marsalek Blahoslav,Blinova Irina,et al.A practical and user-friendly toxicity classification system with microbiotests for natural waters and wastewaters[J].Environmental Toxicology,2003,18(6):395-402.
[37]Wei Dongbin,Tan Zhuowei,Du Yuguo.Toxicity-based assessment of the treatment performance of wastewater treatment and reclamation processes[J].J Environ Sci(China),2012,24(6):969-978.
[38]孟范平,杨菲菲,程凤莲.基于生物标志物指数法的海洋环境评价方法综述[J].应用生态学报,2012(4):1128-1136.
[39]Sanchez Wilfried,Burgeot Thierry,Porcher Jean-Marc.Anovel“Integrated Biomarker Response”calculation based on reference deviation concept[J].Environmental Science and Pollution Research,2012,20(5):2721-2725.
[40]Beliaeff Benoit,Burgeot Thierry.Integrated biomarker response:A useful tool for ecological risk asse-ssment[J].Environmental Toxicology and Chemistry,2002,21(6):1316-1322.
[41]曹宇.农药工业废水的生物毒性评价研究[D].西安:长安大学,2015.
[42]Hafner Christoph,Gartiser Stefan,Garcia-K Ufer Manuel,et al.Investigations on sediment toxicity of German rivers applying a standardized bioassay battery[J].Environmental Science and Pollution Research,2015,22(21):16358-16370.
[43]Jia Ai,Escher Beate I,Leusch Frederic D L,et al.In vitro bioassays to evaluate complex chemical mixtures in recycled water[J].Water Research,2015,801-811.
[44]苏磊.基于海洋倾倒目的之污水污泥化学分析及生物毒性研究[D].上海:上海海洋大学,2015.