我国儿童合理用药的文献研究计量学分析
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摘要
目的为进一步促进我国儿童合理用药研究提供建议。方法运用文献计量学和可视化的方法,采用数据挖掘、信息抽取、关键词共现分析等技术,对知网、万方、维普三大数据库收录的2013—2017年我国儿童合理用药的相关文献进行分析。结果共检索到相关文献14 948篇;从期刊分布来看,文献分布比较广泛,说明儿童合理用药问题受到社会各界的广泛关注;从作者单位分布来看,文献主要来自各儿童医院、妇幼保健院及综合医院,尤其是大学的附属医院是我国儿童合理用药研究的主要力量;由选用的高频关键词看出,我国儿童合理用药的研究热点为抗菌药物或抗生素、糖皮质激素、超说明书用药等方面。结论虽然文献总量很大,但多为对单个医院单因素儿童用药干预前后对比的研究,多地区、多层次、大样本的合理用药研究较少,研究缺乏系统性,研究的广度和深度还有所欠缺。
Objective To provide advice to further promote the rational use of drugs in children.Methods Bibliometric and visualization methods were used through data mining,information extraction,keyword co-occurrence analysis and other techniques to analyze the relevant literature on the rational use of drugs in China from 2013 to 2017 including the three databases of China National Knowledge Internet,Wanfang and Weipu Analyze.Results A total of 14 948 articles were retrieved from the three databases.From the perspective of journal distribution,the literature distribution was quite extensive,indicating that children's rational drug use had received wide attention from all walks of life.From the distribution of authors,the literature mainly came from children's hospitals,maternal and child health centers and comprehensive hospitals,especially affiliated hospitals of universities,which were the main force for the rational use of drugs in children in China.The high-frequency keywords used in the study indicate that the research hotspots of rational use of drugs in China were antibiotics,glucocorticoids,and super-indicative drugs.Conclusion The total amount of literature was very large,but most of them were comparative studies before and after single-factor children's drug intervention in a single hospital.There were few studies on rational drug use in multi-region,multi-level and large-scale samples.The lack of systematic research,the breadth and depth of research was not enough.
Objective To provide advice to further promote the rational use of drugs in children.Methods Bibliometric and visualization methods were used through data mining,information extraction,keyword co-occurrence analysis and other techniques to analyze the relevant literature on the rational use of drugs in China from 2013 to 2017 including the three databases of China National Knowledge Internet,Wanfang and Weipu Analyze.Results A total of 14 948 articles were retrieved from the three databases.From the perspective of journal distribution,the literature distribution was quite extensive,indicating that children's rational drug use had received wide attention from all walks of life.From the distribution of authors,the literature mainly came from children's hospitals,maternal and child health centers and comprehensive hospitals,especially affiliated hospitals of universities,which were the main force for the rational use of drugs in children in China.The high-frequency keywords used in the study indicate that the research hotspots of rational use of drugs in China were antibiotics,glucocorticoids,and super-indicative drugs.Conclusion The total amount of literature was very large,but most of them were comparative studies before and after single-factor children's drug intervention in a single hospital.There were few studies on rational drug use in multi-region,multi-level and large-scale samples.The lack of systematic research,the breadth and depth of research was not enough.
引文
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[10] 姜哲,钟爱娇.糖皮质激素在儿科疾病中的应用现状及合理性分析[J].中国医院药学杂志,2015,35(5):440-443.
[11] 胡宏霞.糖皮质激素类药物临床应用情况分析[J].临床合理用药杂志,2016,9(29):65-66.
[12] 段琼,何荣连.儿童应用中药注射剂的风险因素与控制措施[J].中医药管理杂志,2015,23(9):98-99.
[13] 周彬,张君.儿科应用中药注射剂发生药物不良反应相关因素分析[J].中医儿科杂志,2013,9(5):34-36.
[14] 丁长玲,张树平,赵永德,等.中药注射剂在儿科临床应用的安全性评价研究[J].滨州医学院学报,2013,36(4):256-259.
[15] 张海霞.172例中药注射剂不良反应分析与原因探讨[J].中华中医药杂志,2013,28(2):367-370.
[16] 武文,曾珍.临床药师参与儿科门诊抗菌药物使用干预的效果观察[J].临床合理用药杂志,2016,9(4):1-3.
[17] 阎妍.干预前后天津市儿童医院抗菌药物应用合理性分析[J].中国医院用药评价与分析,2016,16(10):1404-1406.
[18] 钟旭丽,张君莉,王翔岩,等.我院2012年住院患儿抗菌药物使用情况分析[J].儿科药学杂志,2014,20(12):41-44.
[19] 李根,江永贤,梁华,等.我院儿科门诊抗菌药物使用分析[J].儿科药学杂志,2015,21(12):39-42.
[20] 时利玲,张俊霞,冯敏,等.短期小剂量糖皮质激素在儿童难治性肺炎支原体肺炎治疗中的疗效观察[J].中国合理用药探索,2017,14(6):36-38.
[21] 汤银燕,吴灿魁.糖皮质激素辅助治疗儿童肺炎支原体大叶性肺炎的疗效观察[J].临床合理用药杂志,2017,10(29):60-61.
[22] 谢丽君,黄献川,庄俊鹏,等.147例儿童过敏性紫癜患者的用药分析[J].海峡药学,2016,28(11):220-222.
[23] 康清,沙从民.糖皮质激素治疗儿童过敏性紫癜的效果[J].中国保健营养,2017,27(5):317.
[24] 宁静,董汉权,任立歆,等儿童下呼吸道感染病原菌分布及耐药性分析[J].中华医院感染学杂志,2014,24(5):1260-1262.
[25] 李立群,胡静,周凯,等.儿童下呼吸道肺炎链球菌感染临床特征及耐药性[J].中国感染控制杂志,2016,15(8):576-578,582.
[26] 周优丽,沈增晖,姚云,等.他克莫司联合激素对儿童激素耐药难治性肾病综合征的疗效研究[J].儿科药学杂志,2016,22(3):21-23.
[2] 王运锋,夏德宏,颜尧妹,等.社会网络分析与可视化工具NetDraw的应用案例分析[J].现代教育技术,2008,18(4):85-89.
[3] 张梦霞,汪晖,杨纯子,等.护理领导力研究热点的共词聚类分析[J].中华护理杂志,2018,53(2):234-237.
[4] 张幸芝,雷润玲,杨超.文本挖掘:基于ROSTCM和NetDraw的内容分析[J].科技文献信息管理,2017,31(1):17-21,33.
[5] 梅枚,王立波,刘恩梅,等.中国儿童超说明书用药管理现状及认知度的横断面调查[J].中国循证儿科杂志,2017,34(4):289-294.
[6] 朱晓虹,姜德春,刘相佟,等.儿科医师超说明书用药处方行为与认知现状调查[J].儿科药学杂志,2013,19(12):33-37.
[7] 黄丽,陈永法.儿科超说明书用药行为影响因素研究综述[J].现代商贸工业,2013,25(6):160-162.
[8] 郭春彦,王晓玲.大型综合儿童医院门诊患儿超说明书用药情况调查[J].临床药物治疗杂志,2014,12(2):50-55.
[9] 陈植.糖皮质激素在儿科疾病中的应用[J].中国临床医生杂志,2015,43(12):13-15.
[10] 姜哲,钟爱娇.糖皮质激素在儿科疾病中的应用现状及合理性分析[J].中国医院药学杂志,2015,35(5):440-443.
[11] 胡宏霞.糖皮质激素类药物临床应用情况分析[J].临床合理用药杂志,2016,9(29):65-66.
[12] 段琼,何荣连.儿童应用中药注射剂的风险因素与控制措施[J].中医药管理杂志,2015,23(9):98-99.
[13] 周彬,张君.儿科应用中药注射剂发生药物不良反应相关因素分析[J].中医儿科杂志,2013,9(5):34-36.
[14] 丁长玲,张树平,赵永德,等.中药注射剂在儿科临床应用的安全性评价研究[J].滨州医学院学报,2013,36(4):256-259.
[15] 张海霞.172例中药注射剂不良反应分析与原因探讨[J].中华中医药杂志,2013,28(2):367-370.
[16] 武文,曾珍.临床药师参与儿科门诊抗菌药物使用干预的效果观察[J].临床合理用药杂志,2016,9(4):1-3.
[17] 阎妍.干预前后天津市儿童医院抗菌药物应用合理性分析[J].中国医院用药评价与分析,2016,16(10):1404-1406.
[18] 钟旭丽,张君莉,王翔岩,等.我院2012年住院患儿抗菌药物使用情况分析[J].儿科药学杂志,2014,20(12):41-44.
[19] 李根,江永贤,梁华,等.我院儿科门诊抗菌药物使用分析[J].儿科药学杂志,2015,21(12):39-42.
[20] 时利玲,张俊霞,冯敏,等.短期小剂量糖皮质激素在儿童难治性肺炎支原体肺炎治疗中的疗效观察[J].中国合理用药探索,2017,14(6):36-38.
[21] 汤银燕,吴灿魁.糖皮质激素辅助治疗儿童肺炎支原体大叶性肺炎的疗效观察[J].临床合理用药杂志,2017,10(29):60-61.
[22] 谢丽君,黄献川,庄俊鹏,等.147例儿童过敏性紫癜患者的用药分析[J].海峡药学,2016,28(11):220-222.
[23] 康清,沙从民.糖皮质激素治疗儿童过敏性紫癜的效果[J].中国保健营养,2017,27(5):317.
[24] 宁静,董汉权,任立歆,等儿童下呼吸道感染病原菌分布及耐药性分析[J].中华医院感染学杂志,2014,24(5):1260-1262.
[25] 李立群,胡静,周凯,等.儿童下呼吸道肺炎链球菌感染临床特征及耐药性[J].中国感染控制杂志,2016,15(8):576-578,582.
[26] 周优丽,沈增晖,姚云,等.他克莫司联合激素对儿童激素耐药难治性肾病综合征的疗效研究[J].儿科药学杂志,2016,22(3):21-23.