产前硫酸镁和地塞米松干预治疗对早产儿结局的作用分析
摘要
目的:探讨产前硫酸镁和地塞米松干预治疗对早产儿结局的作用。方法:纳入我院2016年4月～2018年4月早产产妇80例,按随机数字表分为对照组和观察组,每组40例。对照组选择利托君+地塞米松治疗,观察组则选择硫酸镁加上地塞米松治疗。比对两组疗效;心率平稳时间、呼吸平稳时间、Apgar评分达到9分时间;施治前后生命体征情况包括血压、呼吸和心率等;早产儿出现肺透明膜病的比例。结果:观察组疗效、心率平稳时间、呼吸平稳时间、Apgar评分达到9分时间、生命体征情况包括血压、呼吸和心率等相比对照组有优势,P<0.05,差异具有统计学意义。观察组早产儿出现肺透明膜病的比例和对照组无显著差异,P>0.05,无统计学意义。结论:硫酸镁加上地塞米松治疗早产疗效肯定。
引文
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[10]Dey,Swatee,Rothe,Helga,Page,Leanne et al.An in vitro Skin Penetration Model for Compromised Skin:Estimating Penetration of Polyethylene Glycol[C-14]-PEG-7 Phosphate[J].Skin pharmacology and physiology,2015,28(1):12-21.
[2]Green,Janet,Darbyshire,Philip,Adams,Anne et al.Looking like a proper baby:nurses'experiences of caring for extremely premature infants[J].Journal of clinical nursing,2015,24(1/2):81-89.
[3]牛峰海,蔡文仙,田玉红,等.产前应用地塞米松对早产儿血糖及胆红素水平的影响[J].中华诊断学电子杂志,2017,5(4):272-276.
[4]Rajkumari Sanatombi Devi,Rajkumari Latasana Devi.Prevalence of Low Birth Weight Infant and its Correlates with Maternal's and Child's Bio-demographic Factors:A Registry Based Study in a Northeast State of India[J].The Indian Journal of Nutrition and Dietetics,2015,52(3):286-294.
[5]宋晶,陈奕.《WHO推荐改善早产结局的干预措施指南》解读[J].北京医学,2016,38(8):749-752.
[6]曹霞.产前单疗程地塞米松干预对早产儿体格和认知发育的影响[J].山东医药,2016,56(12):79-80.
[7]李敏.孕34~35周早产产妇给予促进胎肺成熟治疗的临床研究[J].中国医学创新,2013,10(32):33-34.
[8]Lopez, Olive,Subramanian, Pathmawathi,Rahmat,Norsiah et al.The effect of facilitated tucking on procedural pain control among premature babies[J].Journal of clinical nursing,2015,24(1/2):183-191.
[9]秦巍,陈光福,高红英,等.产前短程应用糖皮质激素对早产儿脑室周围白质软化形成的干预作用[J].中国实用神经疾病杂志,2013,16(12):16-17.
[10]Dey,Swatee,Rothe,Helga,Page,Leanne et al.An in vitro Skin Penetration Model for Compromised Skin:Estimating Penetration of Polyethylene Glycol[C-14]-PEG-7 Phosphate[J].Skin pharmacology and physiology,2015,28(1):12-21.