摘要
<正>妊娠期焦虑是产妇在妊娠期出现各种担忧的具体表现,其中包括对胎儿健康的忧虑,对分娩过程的焦虑,对疼痛的恐惧,对家庭结构变化的不安以及社会功能降低的担忧等~([1])。很多女性在这段时间内可能不表现明显的沮丧或是消沉等症状,但持续进展往往会诱发抑郁~([2]),甚至影响胎儿的发育,增加早产风险~([3])。妊娠期焦虑是困扰女性妊娠过程的一项健康问题,其发病率高达普通人群的3倍~([4])。因此,本文将近年来妊娠期焦虑及其影响因素的研究现状及其进展予以综述,以期提高医护人员对该特殊时段女性心理健康的重视。
引文
[1] MARTINI J,KNAPPE S,BEESDO-BAUM K,et al.Anxiety disorders before birth and self-perceived distress during pregnancy:associations with maternal depression and obstetric,neonatal and early childhood outcomes[J].Early Hum Dev,2010,86(5):305-310.
[2] VAN BUSSEL J C,SPITZ B,DEMYTTENAERE K.Women’s mental health before, during, and after pregnancy:a population-based controlled cohort study[J].Birth,2006,33(4):297-302.
[3] GLYNN L M,SCHETTER C D,HOBEL C J,et al.Pattern of perceived stress and anxiety in pregnancy predicts preterm birth[J].Health Psychol,2008,27(1):43-51.
[4] FAIRBROTHER N,WOODY S R.Fear of childbirth and obstetrical events as predictors of postnatal symptoms of depression and post-traumatic stress disorder[J].J Psychosom Obstet Gynaecol,2007,28(4):239-242.
[5] ALIPOUR Z,LAMYIAN M,HAJIZADEH E.Anxiety and fear of childbirth as predictors of postnatal depression in nulliparous women[J].Women Birth,2012,25(3):e37-e43.
[6] JOKIC-BEGIC N,ZIGIC L,NAKIC RADOS S.Anxiety and anxiety sensitivity as predictors of fear of childbirth:different patterns for nulliparous and parous women[J].J Psychosom Obstet Gynaecol,2014,35(1):22-28.
[7] STORKSEN H T,EBERHARD-GRAN M,GARTHUS-NIEGEL S,et al.Fear of childbirth; the relation to anxiety and depression[J].Acta Obstet Gynecol Scand,2012,91(2):237-242.
[8] MORA P A,BENNETT I M,ELO I T,et al.Distinct trajectories of perinatal depressive symptomatology: evidence from growth mixture modeling[J].Am J Epidemiol,2009,169(1):24-32.
[9] BAYRAMPOUR H,MCDONALD S,TOUGH S.Risk factors of transient and persistent anxiety during pregnancy[J].Midwifery,2015,31(6):582-589.
[10]AUSTIN M P.Antenatal screening and early intervention for“perinatal”distress, depression and anxiety:where to from here[J].Arch Womens Ment Health,2004,7(1):1-6.
[11]NILLNI Y I,MEHRALIZADE A,MAYER L,et al.Treatment of depression, anxiety, and trauma-related disorders during the perinatal period:a systematic review[J].Clin Psychol Rev,2018(66):136-148.
[12]YONKERS K A,NORWITZ E R,SMITH M V,et al.Depression and serotonin reuptake inhibitor treatment as risk factors for preterm birth[J].Epidemiology,2012,23(5):677-685.
[13]FAISAL-CURY A,MENEZES P,ARAYA R,et al.Common mental disorders during pregnancy: prevalence and associated factors among low-income women in So Paulo,Brazil:depression and anxiety during pregnancy[J].Arch Womens Ment Health,2009,12(5):335-343.
[14]WOODS S M,MELVILLE J L,GUO Y,et al.Psychosocial stress during pregnancy[J].Am J Obstet Gynecol,2010,202(1):e1-e7.
[15]ALDERDICE F,LYNN F,LOBEL M.A review and psychometric evaluation of pregnancy-specific stress measures[J].J Psychosom Obstet Gynaecol,2012,33(2):62-77.
[16]Dominguez T P,Dunkel-Schetter C,Glynn L M,et al.Racial differences in birth outcomes:the role of general,pregnancy,and racism stress[J].Health Psychol,2008,27(2):194-203.
[17]JULIAN L J.Measures of anxiety:state-trait anxiety inventory (STAI),beck anxiety inventory (BAI), and hospital anxiety and depression scale-anxiety (HADS-A)[J].Arthritis Care Res (Hoboken),2011,63(Suppl 11):S467-S472.
[18]STERN A F.The hospital anxiety and depression scale[J].Occup Med(Lond),2014,64(5):393-394.
[19]BASTANI F.Effect of acupressure on maternal anxiety in women with gestational diabetes mellitus:a randomized clinical trial[J].Clin Nurs Res,2016,25(3):325-341.
[20]BRUNTON RJ,DRYER R,KRAGELOH C,et al.The pregnancy-related anxiety scale:a validity examination using Rasch analysis[J].J Affect Disord,2018,15(236):127-135.
[21]BERGH B V D.The influence of maternal emotions during pregnancy on fetal and neonatal behavior[J].J Prenatal Perinatal Psychol,1990,5(2):119-130.
[22]SIKKEMA J M,ROBLES DE MEDINA P G,SCHAAD R R,et al.Salivary cortisol levels and anxiety are not increased in women destined to develop preeclampsia[J].J Psychosom Res,2001,50(1):45-49.
[23]ALDER J,FINK N,BITZER J,et al.Depression and anxiety during pregnancy:a risk factor for obstetric,fetal and neonatal outcome?A critical review of the literature[J].J Matern Fetal Neonatal Med,2007,20(3):189-209.
[24]MUZIK M,MCGINNIS E W,BOCKNEK E,et al.PTSD symptoms across pregnancy and early postpartum among women with lifetime PTSD diagnosis[J].Depress Anxiety,2016,33(7):584-591.
[25]Agrati D,Browne D,Jonas W,et al.Maternal anxiety from pregnancy to 2 years postpartum: transactional patterns of maternal early adversity and child temperament[J].Arch Womens Ment Health,2015,18(5):693-705.
[26]YEE L M,LIU L Y,GROBMAN W A.The relationship between obstetricians’ cognitive and affective traits and their patients’ delivery outcomes[J].Am J Obstet Gynecol,2014,211(6):e1-e6.
[27]TOGHER K L,TREACY E,O’KEEFFE G W,et al.Maternal distress in late pregnancy alters obstetric outcomes and the expression of genes important for placental glucocorticoid signalling[J].Psychiatry Res,2017(255):17-26.
[28]DUNKEL SCHETTER C,TANNER L.Anxiety,depression and stress in pregnancy:implications for mothers,children,research,and practice[J].Curr Opin Psychiatry,2012,25(2):141-148.
[29]STEPHANSSON O,KIELER H,HAGLUND B,et al.Selective serotonin reuptake inhibitors during pregnancy and risk of stillbirth and infant mortality[J].JAMA,2013,309(1):48-54.
[30]SOCKOL L E.A systematic review and meta-analysis of interpersonal psychotherapy for perinatal women[J].J Affect Disord,2018,5(232):316-328.
[31]SALMELA-ARO K,READ S,ROUHE H,et al.Promoting positive motherhood among nulliparous pregnant women with an intense fear of childbirth:RCT intervention[J].J Health Psychol,2012,17(4):520-534.
[32]SOCKOL L E.A systematic review of the efficacy of cognitive behavioral therapy for treating and preventing perinatal depression[J].J Affect Disord,2015(177):7-21.
[33]MIHELIC M,MORAWSKA A,FILUS A.Preparing parents for parenthood:protocol for a randomized controlled trial of a preventative parenting intervention for expectant parents[J].BMC Pregnancy Childbirth,2018,18(1):311.
[34]TEIXEIRA J,MARTIN D,PRENDIVILLE O,et al.The effects of acute relaxation on indices of anxiety during pregnancy[J].J Psychosom Obstet Gynaecol,2005,26(4):271-276.