脑出血合并败血症致急性肾损伤1例报告
摘要
<正>近年来,急性肾损伤(acute kidney injury,AKI)在老年人中的发病率呈上升趋势~[1],其常见诱因有:重度感染(例如败血症)、肾毒性药物和心血管事件等~[2,3]。2012年改善全球肾脏病预后组织(KDIGO)对AKI的定义为:48 h内血清肌酐(Scr)升高≥26. 5μmol/L(0. 3 mg/dL);或7 d内Scr升高≥1. 5倍
引文
1程庆砾.老年人肾脏解剖生理学特点与肾脏疾病[J].中华老年医学杂志,2006,25(1):74-76.
2 Hilton R. Acute renal failrue[J]. BMJ,2006,333(7572):786-790.
3 Ali T,Khan I,Simpson W,et al. Incidence and outcomes in acute kidney injury:a comprehensive population-based study[J]. J Am Soc Nephrol,2007,18(4):1292-1298.
4 Khwaja A. KDIGO clinical practice guidelines for acute kidney injury[J]. Nephron Clin Pract,2012,120(4):179-184.
5 Langenberg C,Bagshaw SM,May CN,et al. The histopathology of septic acute kidney injury:a systematic review[J]. Crit Care,2008,12(2):38.
6 李月强,刘晓琴,张炯,等. Akt介导炎症反应参与顺铂诱导的急性肾损伤[J].临床肾脏病杂志,2014,14(5):308-311.
7 Levi M,Vander Poll T,Buller HR. Bidirectional relation between inflammation and coagulation[J]. Circulation,2004,109(22):2698-2704.
8 Barrerachimal J,Pérezvillalva R,Rodríguezromo R,et al. Spironolactone prevents chronic kidney disease caused by ischemic acute kidney injury[J]. Kidney Int,2013,83(1):93-103.
2 Hilton R. Acute renal failrue[J]. BMJ,2006,333(7572):786-790.
3 Ali T,Khan I,Simpson W,et al. Incidence and outcomes in acute kidney injury:a comprehensive population-based study[J]. J Am Soc Nephrol,2007,18(4):1292-1298.
4 Khwaja A. KDIGO clinical practice guidelines for acute kidney injury[J]. Nephron Clin Pract,2012,120(4):179-184.
5 Langenberg C,Bagshaw SM,May CN,et al. The histopathology of septic acute kidney injury:a systematic review[J]. Crit Care,2008,12(2):38.
6 李月强,刘晓琴,张炯,等. Akt介导炎症反应参与顺铂诱导的急性肾损伤[J].临床肾脏病杂志,2014,14(5):308-311.
7 Levi M,Vander Poll T,Buller HR. Bidirectional relation between inflammation and coagulation[J]. Circulation,2004,109(22):2698-2704.
8 Barrerachimal J,Pérezvillalva R,Rodríguezromo R,et al. Spironolactone prevents chronic kidney disease caused by ischemic acute kidney injury[J]. Kidney Int,2013,83(1):93-103.