妊娠合并单核细胞增生性李斯特菌感染的诊治分析
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摘要
李斯特菌病是一种严重的食源性感染性疾病。孕妇患李斯特菌病可导致流产、死胎、早产和先天性新生儿感染等严重妊娠不良结局。单核细胞增多性李斯特菌(Listeria monocytogenes,LM)是引起李斯特菌病的主要病原体类型,虽然其他的细菌感染亦能导致类似的不良妊娠结果,但LM感染与其他病原体感染有显著区别,因其胎儿并发症主要发生在母亲没有明显病灶的情况下,所以有延迟有效医疗干预的风险。为此,本文对妊娠合并LM感染的流行病学特征、感染途径、临床表现、诊断治疗及预后等重要问题进行综述。
引文
[1]王丽丽,陈倩.1例孕妇感染李斯特菌病例的病原学分析及分子特征研究[J].首都公共卫生,2016,10(3):103-106.
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[15]刘红秀,王丽霞.妊娠期产单核李斯特菌感染2例[J].大连医科大学学报,2018,40(3):278-281.
[16]旷凌寒,龚云辉,苏敏,等.妊娠期李斯特菌病19例临床分析[J].中华妇产科杂志,2017,52(10):657-661.
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[18]Ferreira V,Wiedmann M,Teixeira P,et al.Listeria monocytogenes persistence in food-associated environments:epidemiology,strain characteristics,and implications for public health[J].Food Prot,2014,77(1):150-170.
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[22]Kleemann P,Domann E,Chakraborty T,et al.Chronic prosthetic joint infection caused by Listeria monocytogenes[J].J Med Microbiol,2009,58(Pt1):138-141.
[23]Sendi P,Marti E,Fr?hlicher S,et al.Necrotizing fasciitis due to Listeria monocytogenes[J].Clin Infect Dis,2009,48(1):138-139.
[24]Hof H.An update on the medical management of listeriosis[J].Expert Opin Pharmacother,2004,5(8):1727-1735.
[25]Krawczyk-Balska A,Popowska M,Markiewicz Z.Re-evaluation of the significance of penicillin binding protein 3 in the susceptibility of Listeria monocytogenes toβ-lactam antibiotics[J].BMCMicrobiology,2012,12:57.
[26]Pagliano P,Brouwer MC.Comment:“Implementation of a meningitis care bundle in the emergency room reduces mortality associated with acute bacterial meningitis”[J].Ann Pharmacother,2016,50(2):152.
[27]Leiti O,Gross JW,Tuazon CU.Treatment of brain abscess caused by Listeria monocytogenes in a patient with allergy to penicillin and trimethoprim-sulfamethoxazole[J].Clin Infect Dis,2005,40(6):907-908.
[28]Carryn S,Van Bambeke F,Mingeot-Leclercq MP,et al.Activity of beta-lactams(ampicillin,meropenem),gentamicin,azithromycin and moxifloxacin against intracellular Listeria monocytogenes in a24h THP-1 human macrophage model[J].Antimicrob Chemother,2003,51(4):1051-1052.
[29]张固琴,潘华勤,余方,等.妊娠晚期单核细胞增生李斯特菌菌血症一例并文献复习[J].中华全科医师杂志,2018,17(7):551-553.
[2]Swaminathan B,Gerner-Smidt P.The epidemiology of human listeriosis[J].Microbes Infect,2007,9(10):1236-1243.
[3]Allerberger F,Wagner M.Listeriosis:a resurgent foodborne infection[J].Clin Microbiol Infect,2010,16(1):16-23.
[4]Collins S,Ramsay M,Slack MP,et al.Risk of invasive Haemophilus influenzae infection during pregnancy and association with adverse fetal outcomes[J].JAMA,2014,311(11):1125-1132.
[5]Awofisayo A,Amar C,Ruggles R,et al.Pregnancy-associated listeriosis in England and Wales[J].Epidemiol Infect,2015,143(2):249-256.
[6]Leclercq A,Clermont D,Bizet C,et al.Listeria rocourtiae sp.nov[J].Int J Syst Evolution Microbiol,2010,60(Pt9):2210-2214.
[7]Graves LM,Helsel LO,Steigerwalt AG,et al.Listeria marthii sp.Nov.,isolated from natural environment,Finger Lakes National Forest[J].Int J Syst Evol Microbiol,2010,60(Pt 9):1280-1288.
[8]Li Z,Pérez-Osorio A,Wang Y,et al.Whole genome sequencing analyses of Listeria monocytogenes that persisted in a milkshake machine for a year and caused illnesses in Washington State[J].BMC Microbiology,2017,17(1):134.
[9]Silk BJ,Date KA,Jackson KA,et al.Invasive listeriosis in the foodborne diseases active surveillance network(FoodNet),2004-2009:further targeted prevention needed for higher-risk groups[J].Clin Infect Dis,2012,54(5):S396-S404.
[10]Chen Y,Gonzalez-Escalona N,Hammack TS,et al.Core genome multilocus sequence typing for identification of globally distributed clonal groups and differentiation of outbreak strains of Listeria monocytogenes[J].Appl Environ Microbiol,2016,82(20):6258-6272.
[11]Chen Y,Burall LS,Luo Y,et al.Listeria monocytogenes in stone fruits linked to a multistate outbreak:enumeration of cells and whole-genome sequencing[J].Appl Environ Microbiol,2016,82(24):7030-7040.
[12]Charlier C,Perrodeau E,Leclercq A,et al.Clinical features and prognostic factors of listeriosis:the MONALISA National prospective color study[J].Lancet Infect Dis,2017,17(5):510-519.
[13]Smith B,Kemp M,Ethelberg S,et al.Listeria monocytogenes:maternal-foetal infections in Denmark 1994-2005[J].Scand JInfect Dis,2009,41(1):21-25.
[14]许丽,陈慧诊.孕妇感染李斯特菌导致胎死宫内并菌血症1例并文献复习[J].中外女性健康研究,2017,1(2):80-81.
[15]刘红秀,王丽霞.妊娠期产单核李斯特菌感染2例[J].大连医科大学学报,2018,40(3):278-281.
[16]旷凌寒,龚云辉,苏敏,等.妊娠期李斯特菌病19例临床分析[J].中华妇产科杂志,2017,52(10):657-661.
[17]Wang P,Chen Y,Wang H,et al.A clinical analysis of 16 patients with maternal listeriosis[J].Zhonghua Nei Ke Za Zhi,2015,54(9):763-767.
[18]Ferreira V,Wiedmann M,Teixeira P,et al.Listeria monocytogenes persistence in food-associated environments:epidemiology,strain characteristics,and implications for public health[J].Food Prot,2014,77(1):150-170.
[19]Arora N,Sadovsky Y,Dermody TS,et al.Microbial vertical transmission during human pregnancy[J].Cell Host Microbe,2017,21(5):561-567.
[20]Wolfe B,Wiepz GJ,Schotzko M,et al.Acute fetal demise with first trimester maternal infection resulting from Listeria monocytogenes in a nonhuman primate model[J].MBio,2017,8(1):pii:e01938-16.
[21]Girard D,Leclercq A,Laurent E,et al.Pregnancy-related listeriosis in France,1984 to 2011,with a focus on 606 cases from 1999 to2011[J].Euro Surveill,2014,19(38):pii:20909.
[22]Kleemann P,Domann E,Chakraborty T,et al.Chronic prosthetic joint infection caused by Listeria monocytogenes[J].J Med Microbiol,2009,58(Pt1):138-141.
[23]Sendi P,Marti E,Fr?hlicher S,et al.Necrotizing fasciitis due to Listeria monocytogenes[J].Clin Infect Dis,2009,48(1):138-139.
[24]Hof H.An update on the medical management of listeriosis[J].Expert Opin Pharmacother,2004,5(8):1727-1735.
[25]Krawczyk-Balska A,Popowska M,Markiewicz Z.Re-evaluation of the significance of penicillin binding protein 3 in the susceptibility of Listeria monocytogenes toβ-lactam antibiotics[J].BMCMicrobiology,2012,12:57.
[26]Pagliano P,Brouwer MC.Comment:“Implementation of a meningitis care bundle in the emergency room reduces mortality associated with acute bacterial meningitis”[J].Ann Pharmacother,2016,50(2):152.
[27]Leiti O,Gross JW,Tuazon CU.Treatment of brain abscess caused by Listeria monocytogenes in a patient with allergy to penicillin and trimethoprim-sulfamethoxazole[J].Clin Infect Dis,2005,40(6):907-908.
[28]Carryn S,Van Bambeke F,Mingeot-Leclercq MP,et al.Activity of beta-lactams(ampicillin,meropenem),gentamicin,azithromycin and moxifloxacin against intracellular Listeria monocytogenes in a24h THP-1 human macrophage model[J].Antimicrob Chemother,2003,51(4):1051-1052.
[29]张固琴,潘华勤,余方,等.妊娠晚期单核细胞增生李斯特菌菌血症一例并文献复习[J].中华全科医师杂志,2018,17(7):551-553.