成人阻塞性睡眠呼吸暂停的危险因素分析
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摘要
目的探讨不同严重程度分级的成人阻塞性睡眠呼吸暂停(obstructive sleep apnea,OSA)的危险因素。方法选取我院呼吸睡眠中心行多导睡眠监测(polysomnography,PSG)确诊的成人OSA患者103例,分析年龄、性别、BMI、颈长、颈围、颈围颈长比、胸围、腹围、腹围/体重等因素与OSA病情严重程度的关系。结果 BMI值、腹围、颈围和颈长是影响OSA患者严重程度的高危因素。结论 OSA患者的严重程度与BMI、颈围、颈长、腹围等危险因素有关,可根据危险因素,早期筛查及诊治。
Objective To investigate the relationship between risk factors and apnea hypopnea indexes(AHI) in adults with obstructive sleep apnea(OSA). Methods A total of 103 adult OSA patients diagnosed by polysomnography(PSG) were included, and the associations of age, gender, BMI, neck length, neck circumference, neck circumference ratio, chest circumference, abdominal circumference, abdominal circumference/body weight and other factors with the severity of OSA were analyzed. Results BMI, abdominal circumference, neck circumference and neck length were main factors affecting the AHI level of OSA patients. Conclusion OSA patients with different severity have a relationship with risk factors such as BMI, neck circumference, neck length and abdominal circumference, and early screening and diagnosis can be made according to the risk factors.
Objective To investigate the relationship between risk factors and apnea hypopnea indexes(AHI) in adults with obstructive sleep apnea(OSA). Methods A total of 103 adult OSA patients diagnosed by polysomnography(PSG) were included, and the associations of age, gender, BMI, neck length, neck circumference, neck circumference ratio, chest circumference, abdominal circumference, abdominal circumference/body weight and other factors with the severity of OSA were analyzed. Results BMI, abdominal circumference, neck circumference and neck length were main factors affecting the AHI level of OSA patients. Conclusion OSA patients with different severity have a relationship with risk factors such as BMI, neck circumference, neck length and abdominal circumference, and early screening and diagnosis can be made according to the risk factors.
引文
[1]高和,崔丽,段莹.睡眠障碍国际分类第3版翻译版[M].北京:人民卫生出版社,2017:24-31.
[2]穆雪鹃,李亚珍,魏永莉等,《2014美国医师协会成人阻塞性睡眠呼吸暂停诊断临床实践指南》解读[J].中国急救医学,2015,35(1):1-4.
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[4]陈宝元,何权瀛.阻塞性睡眠呼吸暂停综合征的系统性损害[J].中华医学杂志,2012,92(18):1225-1227.
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[7]中国医师协会睡眠医学专业委员会.成人阻塞性睡眠呼吸暂停多学科诊疗指南[J].中华医学杂志,2018,98(24):1902-1914.
[8]闫涵,董霄松.便携式睡眠监测代替多导睡眠监测诊断在我国广泛应用尚不成熟[J].中华结核和呼吸杂志,2014,37(12):947-948.
[9]孙楷,聂洪玉,徐东兰.鼾症患者中阻塞性睡眠呼吸暂停低通气综合征的筛查及危险因素分析[J].中国呼吸与危重监护杂志,2019,18(1):26-30.
[10]王卉,许健峰,陈立平.睡眠呼吸暂停综合征的相关危险因素研究[J].西北国防医学杂志,2018,39(6):379-382.
[11]Deng X,Gu W,Li Y,et al.Age-group-specific associations between the severity of obstructive sleep apnea and relevant risk factorsin male and female patients[J].Plo S One,2014,9(9):107380.
[12]Li Z,Li Y,Yang L,et al.Characterization of obstructive sleep apnea in patients with insomnia across gender and age[J].Sleep Breath,2015,19(2):723-727.
[13]李庆云,李宁.肥胖与阻塞性睡眠呼吸暂停低通气综合征-呼吸内科视角[J].中华肥胖与代谢病电子杂志,2018,4(2):80-83.
[14]Han T S,Mi KO,Su M K,et al.Relationship between Neck Length,Sleep and Cardiovascular Risk factors[J].Korean J Fam Med,2015,36(1):10-21.
[2]穆雪鹃,李亚珍,魏永莉等,《2014美国医师协会成人阻塞性睡眠呼吸暂停诊断临床实践指南》解读[J].中国急救医学,2015,35(1):1-4.
[3]Sutherland K,Cistulli PA.Recent advances in obstructive sleep apnea pathophysiology and treatment[J].Sleep Biol Rhythm,2015,13(1):26-40.
[4]陈宝元,何权瀛.阻塞性睡眠呼吸暂停综合征的系统性损害[J].中华医学杂志,2012,92(18):1225-1227.
[5]Berry RB,Brooks R,Gamaldo CE,et al.The AASM manual for thescoring of sleep and associated events:rules,terminology and technical specifications[M].VERSION 2.3.Darien IL:AmericanAcademy of Sleep Medicine,2016:18-61
[6]何权瀛,王莞尔.阻塞性睡眠呼吸暂停低通气综合征诊治指南(基层版)[J].中国呼吸与危重监护杂志,2015,14(4):398-405.
[7]中国医师协会睡眠医学专业委员会.成人阻塞性睡眠呼吸暂停多学科诊疗指南[J].中华医学杂志,2018,98(24):1902-1914.
[8]闫涵,董霄松.便携式睡眠监测代替多导睡眠监测诊断在我国广泛应用尚不成熟[J].中华结核和呼吸杂志,2014,37(12):947-948.
[9]孙楷,聂洪玉,徐东兰.鼾症患者中阻塞性睡眠呼吸暂停低通气综合征的筛查及危险因素分析[J].中国呼吸与危重监护杂志,2019,18(1):26-30.
[10]王卉,许健峰,陈立平.睡眠呼吸暂停综合征的相关危险因素研究[J].西北国防医学杂志,2018,39(6):379-382.
[11]Deng X,Gu W,Li Y,et al.Age-group-specific associations between the severity of obstructive sleep apnea and relevant risk factorsin male and female patients[J].Plo S One,2014,9(9):107380.
[12]Li Z,Li Y,Yang L,et al.Characterization of obstructive sleep apnea in patients with insomnia across gender and age[J].Sleep Breath,2015,19(2):723-727.
[13]李庆云,李宁.肥胖与阻塞性睡眠呼吸暂停低通气综合征-呼吸内科视角[J].中华肥胖与代谢病电子杂志,2018,4(2):80-83.
[14]Han T S,Mi KO,Su M K,et al.Relationship between Neck Length,Sleep and Cardiovascular Risk factors[J].Korean J Fam Med,2015,36(1):10-21.