冠状动脉左主干病变介入治疗临床研究
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摘要
目的:探讨冠脉内支架植入术(PCI)与冠脉搭桥术(CABG)治疗无保护左主干病变(ULMCA)的疗效。方法:选取我院45例采用PCI治疗与31例采用CABG治疗的ULMCA患者的临床资料,对2组患者的SYNTAX score评分与EURO score积分进行评估,同时对2组患者的危险因素进行比较研究。结果:比较PCI组与CABG组患者的危险因素,结果表明,2组患者在危险因素上不存在显著性差异(P>0.05);同时比较了2组患者的EURO score与SYNTAX score,结果表明,2组患者在EURO score与SYNTAX score上均不存在显著性差异(P>0.05)。结论:对于ULMCA患者,通过SYNTAX score与EURO score以及危险因素进行评估,若属于低危患者或中危患者,则使用PCI治疗是安全可靠的,创伤小而恢复快,并且能够取得满意的临床疗效,与CABG治疗结果相比无显著性差异。
Objective: To study the unprotected left main lesion( ULMCA) curative effect between the intravascular stent implantation( PCI) and coronary artery bypass surgery( CABG). Methods: 45 cases were treated by PCI and 31 cases by CABG in all patients with ULMCA,the two groups of patients were assessed with SYNTAX Score Score with EURO Score,and compared the risk factors in two groups of patients. Results: Compared PCI group with CABG group,there was no significant differences in risk factors( P > 0. 05) and there was no significant difference in EURO score and SYNTAX score( P > 0. 05). Conclusion: For patients with ULMCA,and risk factors of SYNTAX Score,EURO Score are low or moderate,the PCI therapy are safe and reliable,little trauma and quick recovery,and can obtain satisfactory clinical effect,and compare with CABG therapy,there is no significant difference.
Objective: To study the unprotected left main lesion( ULMCA) curative effect between the intravascular stent implantation( PCI) and coronary artery bypass surgery( CABG). Methods: 45 cases were treated by PCI and 31 cases by CABG in all patients with ULMCA,the two groups of patients were assessed with SYNTAX Score Score with EURO Score,and compared the risk factors in two groups of patients. Results: Compared PCI group with CABG group,there was no significant differences in risk factors( P > 0. 05) and there was no significant difference in EURO score and SYNTAX score( P > 0. 05). Conclusion: For patients with ULMCA,and risk factors of SYNTAX Score,EURO Score are low or moderate,the PCI therapy are safe and reliable,little trauma and quick recovery,and can obtain satisfactory clinical effect,and compare with CABG therapy,there is no significant difference.
引文
[1]马玲玲,于清波,孙银霞.一例冠状动脉左主干病变成功介入治疗的护理[J].护士进修杂志,2009,24(18):1723-1725.
[2]Holmes DR,Nishimura R,Fountain R,et al.Iatrogenic pericardial effusion and tamponade in the percutaneous intracardiac intervention era[J].JACC Cardiovase Interv,2009,2(8):705-717.
[3]Brener S J,Molitemo D J,Aylward PE,et al.Reperfusion after primary angioplasty for ST-elevation myocardial infarction:predictors of succ III and relationship to clinical outcomes in the APEX-AMI angiographic study[J].Eur Heart J,2008,29(9):1127-1135.
[4]杨胜利,刘惠亮.冠状动脉左主干病变介入治疗进展[J].中华老年心脑血管病杂志,2011,13(11):1043-1045.
[5]Chieffo A,Park S J,Valgimigli M,et al.Favorable long-term outcome after drug eluting stentimplantation in nonbifurcation lesions that involve unprotected left main coronary artery:a multicenter registry[J].Circulation,2007,116(2):158-162.
[6]朱国英.从适应证及禁忌证的变迁看冠心病介入治疗的进步[J].基础医学与临床,2006,26(4):337.
[7]胡新荣,金新新.冠状动脉左主干病变的治疗对策[J].河南科技大学学报,2007,25(3):188-191.
[2]Holmes DR,Nishimura R,Fountain R,et al.Iatrogenic pericardial effusion and tamponade in the percutaneous intracardiac intervention era[J].JACC Cardiovase Interv,2009,2(8):705-717.
[3]Brener S J,Molitemo D J,Aylward PE,et al.Reperfusion after primary angioplasty for ST-elevation myocardial infarction:predictors of succ III and relationship to clinical outcomes in the APEX-AMI angiographic study[J].Eur Heart J,2008,29(9):1127-1135.
[4]杨胜利,刘惠亮.冠状动脉左主干病变介入治疗进展[J].中华老年心脑血管病杂志,2011,13(11):1043-1045.
[5]Chieffo A,Park S J,Valgimigli M,et al.Favorable long-term outcome after drug eluting stentimplantation in nonbifurcation lesions that involve unprotected left main coronary artery:a multicenter registry[J].Circulation,2007,116(2):158-162.
[6]朱国英.从适应证及禁忌证的变迁看冠心病介入治疗的进步[J].基础医学与临床,2006,26(4):337.
[7]胡新荣,金新新.冠状动脉左主干病变的治疗对策[J].河南科技大学学报,2007,25(3):188-191.