调肝理脾颗粒治疗小儿厌食症30例临床观察
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摘要
目的:观察调肝理脾颗粒治疗小儿厌食症(脾虚肝旺型)的临床疗效。方法:将60例厌食症(脾虚肝旺型)患儿随机分为治疗组和对照组各30例,治疗组采用自拟方调肝理脾颗粒治疗,对照组采用枯草杆菌二联活菌颗粒治疗,疗程均为4周,比较2组临床疗效。结果:总有效率治疗组为100. 0%,对照组为86. 7%,2组比较,差异有统计学意义(P <0. 05); 2组主要症状积分治疗前后组内比较及治疗后组间比较,差异均有统计学意义(P <0. 05)。2组均未发生不良反应。结论:调肝理脾颗粒治疗小儿厌食症(脾虚肝旺型)有较好疗效。
Objective: To investigate the clinical effect of Tiaogan Lipi granules in the treatment of infantile anorexia with spleen deficiency and liver-Yang hyperactivity. Methods: A total of 60 children with infantile anorexia with spleen deficiency and liver-Yang hyperactivity were randomly divided into treatment group and control group,with 30 children in each group. The children in the treatment group were given self-made Tiaogan Lipi granules,and those in the control group were given live combined Bacillus subtilis and Enterococcus faecium granules. The course of treatment was 4 weeks for both groups,and clinical outcome was compared between the two groups. Results: There was a significant difference in overall response rate between the treatment group and the control group( 100. 0% vs 86. 7%,P < 0. 05). Both groups had significant changes in the scores of main symptoms after treatment,and there were significant differences in these scores between the two groups( P < 0. 05). No adverse events were observed. Conclusion: Tiaogan Lipi granules have a good clinical effect in the treatment of infantile anorexia with spleen deficiency and liver-Yang hyperactivity.
Objective: To investigate the clinical effect of Tiaogan Lipi granules in the treatment of infantile anorexia with spleen deficiency and liver-Yang hyperactivity. Methods: A total of 60 children with infantile anorexia with spleen deficiency and liver-Yang hyperactivity were randomly divided into treatment group and control group,with 30 children in each group. The children in the treatment group were given self-made Tiaogan Lipi granules,and those in the control group were given live combined Bacillus subtilis and Enterococcus faecium granules. The course of treatment was 4 weeks for both groups,and clinical outcome was compared between the two groups. Results: There was a significant difference in overall response rate between the treatment group and the control group( 100. 0% vs 86. 7%,P < 0. 05). Both groups had significant changes in the scores of main symptoms after treatment,and there were significant differences in these scores between the two groups( P < 0. 05). No adverse events were observed. Conclusion: Tiaogan Lipi granules have a good clinical effect in the treatment of infantile anorexia with spleen deficiency and liver-Yang hyperactivity.
引文
[1]杨伟晗,独家能,许雯雯,等.中西医治疗小儿厌食症研究概况[J].中医药临床杂志,2017,29(11):1979-1982.
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[4]马融,胡思源,王俊宏,等.小儿厌食中药新药临床试验设计与评价技术指南[S].药物评价研究,2015,38(3):244-250.
[5]郑筱萸.中药新药临床研究指导原则[S].北京:中国医药科技出版社,2002:267-269.
[2]陈珊红,周盈.小儿厌食症的中西医研究进展[J].新疆中医药,2018(1):117-120.
[3]胡亚美,江载芳,诸福棠.诸福棠实用儿科学(7版)[M].北京:人民卫生出版社,2002:1294.
[4]马融,胡思源,王俊宏,等.小儿厌食中药新药临床试验设计与评价技术指南[S].药物评价研究,2015,38(3):244-250.
[5]郑筱萸.中药新药临床研究指导原则[S].北京:中国医药科技出版社,2002:267-269.