地佐辛注射液依赖共病抑郁症一例
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摘要
<正>1病例摘要患者,女,40岁,因反复滥用苯二氮艹卓类药物5年,地佐辛注射液1年,停用后恶心、发冷发热、烦躁不安4小时于2018年10月18日入住长沙市自愿戒毒中心治疗。患者于2013年因家庭重大变故出现持续情绪低落,失眠,既往兴趣丧失,有自责感,并服用地西泮片及阿普唑仑片共计150余粒自杀,服用后仅感胸闷不适,入睡一天后无其他不适,未做任何处理。之后在与家人争吵或烦躁时,间断服用阿普唑仑片2-3片或佐匹克隆片1片助眠和缓解烦躁情绪,不
引文
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[7] Substance abuse and mental health services administration,Center for substance abuse treatment. a treatment improvement protocol-42:Substance abuse treatment for persons with co-oc-curring disorders[M]. Department of health and human services(HHSs),2005,2-27.
[8]Kessler RC,McGonagle KA,Zhao S,et al. Lifetime and 12month prevalence of DSM-Ⅲ-R psychiatric disorders in the United States. Results from the National Comorbidity Survey[J]. Arch Gen Psychiatry,1994,51(1):8-19.
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[11]张陈茜,向小军,郝伟.物质使用障碍与抑郁症共病[J].中国药物滥用防治杂志,2013,(4):216-220.
[12]段宝海.强制戒毒者的成瘾程度与抑郁状况和自杀意念的相关分析[J].中国药物滥用防治杂志,2010,(2):70-72.
[13]胡建,陆林,等.中国物质使用障碍防治指南[M].北京:中华医学电子音像出版社,2015:148-198.
[2]Chartoff E,Sawyer A,Rachlin A,et al. Blockade of kappa opioid receptors attenuates the development of depressive-like behaviors induced by cocaine withdrawal in rats[J]. Neuropharmacology,2012,62(1):167-176. doi:10. 1016/j.Neuropharm. 2011. 06. 014.
[3]Carr GV,Bangasser DA,Bethea T,et al. Antidepressant-like effects of kappa-opioid receptor antagonists in Wistar Kyoto Rats[J]. Neuropsychopharmacology,2010,35(3):752-763. doi:10. 1038/npp. 2009. 183.
[4]Jonesuu M,Tolmunen T,Saarinen PI,et al. Reduced midbrain serotonin transporter availability in drug-naive patients with depression measured by SERT-specific[(123)I]nor-beta-CIT SPECT imaging[J]. Psychiatry Res,2007,154(2):125-131. doi:10. 1016/j. pscychresns. 2006. 08. 001.
[5]Gilman KW,Parker MF,Silva M,et al. Design,optimization,and in vivo evaluation of a series of pyridine derivatives with dual NK1 antagonism and SERT inhibition for the treatment of depression[J]. Bioorg Med Chem Lett,2013,23(2):407-411.
[6]刘铁桥,赵敏,等.苯二氮艹卓类药物临床使用专家共识[M].北京:人民卫生出版社,2016:7-21.
[7] Substance abuse and mental health services administration,Center for substance abuse treatment. a treatment improvement protocol-42:Substance abuse treatment for persons with co-oc-curring disorders[M]. Department of health and human services(HHSs),2005,2-27.
[8]Kessler RC,McGonagle KA,Zhao S,et al. Lifetime and 12month prevalence of DSM-Ⅲ-R psychiatric disorders in the United States. Results from the National Comorbidity Survey[J]. Arch Gen Psychiatry,1994,51(1):8-19.
[9]郝伟,赵敏,李锦,等.成瘾医学理论与实践[M].北京:人民卫生出版社,2016:238-252.
[10]Grant BF,Stinson FS,Dawson DA,et al. Prevalence and co-occurrence of substance use disorders and in dependent mood and anxiety disorders:results from the National Epidemiologic Survey on Alcohol and Related Conditions[J]. Arch Gen Psychiatry,2004,61(8):807-816.
[11]张陈茜,向小军,郝伟.物质使用障碍与抑郁症共病[J].中国药物滥用防治杂志,2013,(4):216-220.
[12]段宝海.强制戒毒者的成瘾程度与抑郁状况和自杀意念的相关分析[J].中国药物滥用防治杂志,2010,(2):70-72.
[13]胡建,陆林,等.中国物质使用障碍防治指南[M].北京:中华医学电子音像出版社,2015:148-198.