低剂量CT引导肺小结节活检的临床价值分析
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摘要
目的探讨低剂量CT引导对肺小结节活检的临床价值。方法选择我院收治的手术后病理学检查确诊为患有肺小结节疾病的患者84例,随机分为对照组和研究组,每组各42例。对照组采用常规剂量CT检查;研究组采用低剂量CT引导活检技术检查。对两组患者检查结果与术后病理学证实结果进行对比分析。结果研究组在手术治疗前CT检查结果与术后病理学证实结果的符合率明显高于对照组(P<0.05);检查时间明显短于对照组(P<0.05);肺小结节疾病临床诊断的误诊和漏诊率明显少于对照组(P<0.05)。结论应用低剂量CT引导技术对患有肺小结节疾病的患者实施活检具有符合率较高、误诊和漏诊率低、操作时间短等优点,具有一定的临床价值。
Objective To investigate the clinical value of low-dose CT guidance on pulmonary nodule biopsy. Methods A total of 84 patients with pulmonary nodule disease who were diagnosed by postoperative examination in our hospital were randomly divided into control group and study group, with 42 patients in each group. The control group was given routine dose CT examination; the study group was given biopsy guided by low-dose CT. The examination results and confirmed results of postoperative pathology were compared and analyzed in the two groups of patients. Results The coincidence rate between the CT findings before the surgical treatment and postoperative pathologically confirmed results in the study group was significantly higher than that in the control group(P<0.05); The examination time was shorter than that of the control group(P<0.05); the rate of misdiagnosis and missed diagnosis of pulmonary nodule disease was significantly lower than that of control group(P<0.05). Conclusion The low-dose CT guided technique has a higher coincidence rate in the patients with pulmonary nodule disease undergone biopsy. It has a certain clinical value in reducing the rate of misdiagnosis and missed diagnosis rate and shorting operation time.
Objective To investigate the clinical value of low-dose CT guidance on pulmonary nodule biopsy. Methods A total of 84 patients with pulmonary nodule disease who were diagnosed by postoperative examination in our hospital were randomly divided into control group and study group, with 42 patients in each group. The control group was given routine dose CT examination; the study group was given biopsy guided by low-dose CT. The examination results and confirmed results of postoperative pathology were compared and analyzed in the two groups of patients. Results The coincidence rate between the CT findings before the surgical treatment and postoperative pathologically confirmed results in the study group was significantly higher than that in the control group(P<0.05); The examination time was shorter than that of the control group(P<0.05); the rate of misdiagnosis and missed diagnosis of pulmonary nodule disease was significantly lower than that of control group(P<0.05). Conclusion The low-dose CT guided technique has a higher coincidence rate in the patients with pulmonary nodule disease undergone biopsy. It has a certain clinical value in reducing the rate of misdiagnosis and missed diagnosis rate and shorting operation time.
引文
[1]王臣,嵇鸣,叶春涛.低剂量CT引导肺小结节活检的应用[J].中国医学影像学杂志,2014,22(4):297-299,304.
[2]刘士远,于红.积极推进胸部低剂量CT扫描的临床应用[J].中华放射学杂志,2010,38(1):6-7.
[3]刘长军,李洪松.64排螺旋CT在肺结节病变经皮穿刺活检中的临床应用研究[J].实用医学影像杂志,2012,13(6):367-370.
[4]王斌,伍安,范晔,等.CT引导下经皮肺穿刺活检对肺部恶性肿瘤的诊断价值[J].中华医学杂志,2013,93(38):3023-3026.
[5]田葵,沙晋璐,余辉山.低剂量CT引导下肺穿刺活检的临床应用价值评估[J].中国防痨杂志,2013,35(2):111-115.
[6]邹礼明,潘承欣,杨接辉,等.CT引导下经皮肺穿刺活检对肺小结节的诊断价值[J].肿瘤研究与临床,2007,19(2):90-91.
[7]于爱阳.肺错构瘤16例CT诊断分析[J].中国误诊学杂志,2009,9(9):2220-2221.
[8]Atwell TD,Smith RL,Hesley G.Incidence of bleeding after15,181 percutaneous biopsies and the role of aspirin[J].AJR,2010,194(3):784-789.
[9]莫云海,冉隆富,杜涛明,等.多层螺旋CT对肺炎型肺癌的影像及其病理的相关性研究[J].实用医学影像杂志,2014,15(6):3023-3026.
[10]公维宏,王军业,赵海燕,等.CT引导下经皮穿刺肺活检术的技术探讨与并发症分析[J].国际肿瘤学杂志,2014,41(11):869-872.
[11]邱宁雷,张治,庄一平,等.肺部小结节胸腔镜术前CT引导下硬化剂定位的临床应用价值[J].中华胸心血管外科杂志,2012,28(7):398-399.
[12]孙梅.CT引导下穿刺联合亚甲蓝定位在肺小结节微创术中的应用及护理[J].临床肺科杂志,2013,18(6):1150-1151.
[13]刘大亮,马大庆,陈广.CT的分叶征表现在肺内孤立结节影像诊断中的价值[J].中华放射学杂志,2013,41(15):488-489.
[14]周燕发,田芳,陈辉.肺内球形灶棘突CT征与病理对照研究[J].临床放射学杂志,2012,21(13):199-200.
[15]张殿星,武乐斌,田军,等.畅数字化断层融合对肺内小结节检出价值的ROC曲线评价[J].实用放射学杂志,2011,20(11):1659-1660.
[16]孟宪平,谢旭刚,朱建新,等.超高分辨率CT在肺部小结节诊断中的应用[J].实用临床医药杂志,2011,15(24):179-180.
[2]刘士远,于红.积极推进胸部低剂量CT扫描的临床应用[J].中华放射学杂志,2010,38(1):6-7.
[3]刘长军,李洪松.64排螺旋CT在肺结节病变经皮穿刺活检中的临床应用研究[J].实用医学影像杂志,2012,13(6):367-370.
[4]王斌,伍安,范晔,等.CT引导下经皮肺穿刺活检对肺部恶性肿瘤的诊断价值[J].中华医学杂志,2013,93(38):3023-3026.
[5]田葵,沙晋璐,余辉山.低剂量CT引导下肺穿刺活检的临床应用价值评估[J].中国防痨杂志,2013,35(2):111-115.
[6]邹礼明,潘承欣,杨接辉,等.CT引导下经皮肺穿刺活检对肺小结节的诊断价值[J].肿瘤研究与临床,2007,19(2):90-91.
[7]于爱阳.肺错构瘤16例CT诊断分析[J].中国误诊学杂志,2009,9(9):2220-2221.
[8]Atwell TD,Smith RL,Hesley G.Incidence of bleeding after15,181 percutaneous biopsies and the role of aspirin[J].AJR,2010,194(3):784-789.
[9]莫云海,冉隆富,杜涛明,等.多层螺旋CT对肺炎型肺癌的影像及其病理的相关性研究[J].实用医学影像杂志,2014,15(6):3023-3026.
[10]公维宏,王军业,赵海燕,等.CT引导下经皮穿刺肺活检术的技术探讨与并发症分析[J].国际肿瘤学杂志,2014,41(11):869-872.
[11]邱宁雷,张治,庄一平,等.肺部小结节胸腔镜术前CT引导下硬化剂定位的临床应用价值[J].中华胸心血管外科杂志,2012,28(7):398-399.
[12]孙梅.CT引导下穿刺联合亚甲蓝定位在肺小结节微创术中的应用及护理[J].临床肺科杂志,2013,18(6):1150-1151.
[13]刘大亮,马大庆,陈广.CT的分叶征表现在肺内孤立结节影像诊断中的价值[J].中华放射学杂志,2013,41(15):488-489.
[14]周燕发,田芳,陈辉.肺内球形灶棘突CT征与病理对照研究[J].临床放射学杂志,2012,21(13):199-200.
[15]张殿星,武乐斌,田军,等.畅数字化断层融合对肺内小结节检出价值的ROC曲线评价[J].实用放射学杂志,2011,20(11):1659-1660.
[16]孟宪平,谢旭刚,朱建新,等.超高分辨率CT在肺部小结节诊断中的应用[J].实用临床医药杂志,2011,15(24):179-180.