花叶九节木化学成分的研究
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摘要
为研究花叶九节木[Psychotria siamica(Craib)Hutch.]中的化学成分,采用硅胶柱色谱、重结晶等方法分离和纯化,并通过波谱学方法鉴定其化学成分的结构。结果表明,从花叶九节木中分离得到7个化合物,经波谱解析确定化合物分别为正三十五烷、正二十四烷酸、正二十六烷酸、β-谷甾醇、熊果酸、间苯二酚、胡萝卜苷,这是首次从该植物中分离得到上述7种化合物。
To study the chemical constituents of Psychotria siamica(Craib) Hutch.. The methods of silica column chromatography and recrystallization were used to isolate and purify the chemical constituents of P. siamica. Seven compounds were isolated and identified as n-pentatriacontane, n-tetracosanoic acid, n-hexacosanoic acid, β-sitosterol,ursolic acid,resorcinol,daucosterol. The seven compounds were isolated from this plant for the first time.
To study the chemical constituents of Psychotria siamica(Craib) Hutch.. The methods of silica column chromatography and recrystallization were used to isolate and purify the chemical constituents of P. siamica. Seven compounds were isolated and identified as n-pentatriacontane, n-tetracosanoic acid, n-hexacosanoic acid, β-sitosterol,ursolic acid,resorcinol,daucosterol. The seven compounds were isolated from this plant for the first time.
引文
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[3]国家中医药管理局《中华本草》编辑委员会.中华本草(第六册)[M].上海:上海科学技术出版社,1999.468.
[4]HAILEMICHAEL T,WILFRIED A K.Terpenes from Otostegia integrifolia[J].Phytochemistry,2004,65(14):2057-2062.
[5]CHUNG I M,ALI M,KHANH T D,et al.New stigmastane steroids constituents from rice hulls of Oryza sativa and inhibitory activity on radish seed[J].Bull Korean Chem Soc,2006,27(1):93-98.
[6]赵庆春,付艳辉,郭涛,等.胡蔓藤中非生物碱类化学成分的分离与鉴定[J].沈阳药科大学学报,2007,24(10):619-622.
[7]张纪达,胡英杰,张文,等.铁甲草化学成分的初步研究[J].热带亚热带植物学报,2009,17(1):80-82.
[8]赵琴,梁锐君,张玉洁,等.余甘子根的化学成分研究[J].中草药,2013,44(2):133-136.
[9]林艳芹,郑薇,黄鹤光.熊果酸对急性肝损伤动物模型作用的研究[J].福建医药杂志,2014,36(4):63-65.
[10]谢艳茹,周月芬.熊果酸诱导人肝癌SMMC-7721细胞凋亡的研究[J].中西医结合肝病杂志,2011,21(3):154-155,172.
[11]孙瑞娜,张艳妮,汪俊,等.女贞子抗丙型肝炎病毒复制酶活性成分研究[J].药学学报,2013,48(9):1390-1396.