中药内服联合外敷治疗异位妊娠保守治疗后输卵管积液患者的疗效观察
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摘要
目的探讨内服温阳活血中药联合局部外敷中药治疗异位妊娠保守治疗后输卵管积液患者的临床疗效。方法收集2014年1月至2016年1月期间广州市妇女儿童医疗中心中医妇科门诊就诊的异位妊娠保守治疗后,彩超提示单侧和或双侧输卵管积液患者64例作为研究对象,随机分为观察组和对照组,各32例。观察组患者采用口服温阳活血中药方剂(熟附子、桂枝、丹参、丹皮、赤芍、桃仁、厚朴、黄芪、白术)治疗,外敷中药四黄散(大黄粉、黄连粉、黄柏粉、黄芩粉),对照组患者予康妇消炎栓塞肛治疗,治疗3个月经周期。观察两组患者治疗后中医证候评分、治疗有效率以及安全性比较。结果经治疗,观察组患者治疗有效率为81.2%,高于对照组的50.0%,差异有统计学意义(P<0.05)。两组患者治疗后中医证候评分比较,观察组患者的月经改变、腰骶部酸痛、下腹隐痛评分均低于对照组,差异均有统计学意义(均P<0.05)。结论温阳活血法联合局部外敷中药治疗可以改善异位妊娠保守治疗后输卵管积液患者的临床症状,改善输卵管局部炎症情况,促进炎症及输卵管积液的吸收。
Objective To observe the therapeutic effect of Traditional Chinese Medicine combined with external application in treating patients with tubal hydrops after actopic pregnancy.Methods From January 2014 to January 2016,collect a total of 64 cases of patients with tubal effusion were presented by color Doppler ultrasound after conservative treatment because of ectopic pregnancy from the Chinese medicine gynecology department of our hospital.The patients divide into treatment group and control group,the treatment group patients accepted oral Traditional Chinese Medicine(TCM) and external appliction TCM,and the control group patients only use kanfuxiaoyan suppository,Observe two groups of effective and symptomatic scores afer three months treatment.Results Afler the course of treatment,the total efficiency of the treatment group was 81.2%,is higher than the control group's 50.0%(P<0.05).Two groups of patients after treatment of TCM syndrome score comparison, the observation group after treatment of menstrual changes, lumbar di ministry ache, abdominal dull pain scores were lower than control group, the differences were statistically significant(all P<0.05).Conclusion The treatment of warning yang and promoting blood and Traditional Chinese Medicine combined with external application show certain therapeutic effect for tubal hydrops after actopic pregnancy and remit clinical symptoms.
Objective To observe the therapeutic effect of Traditional Chinese Medicine combined with external application in treating patients with tubal hydrops after actopic pregnancy.Methods From January 2014 to January 2016,collect a total of 64 cases of patients with tubal effusion were presented by color Doppler ultrasound after conservative treatment because of ectopic pregnancy from the Chinese medicine gynecology department of our hospital.The patients divide into treatment group and control group,the treatment group patients accepted oral Traditional Chinese Medicine(TCM) and external appliction TCM,and the control group patients only use kanfuxiaoyan suppository,Observe two groups of effective and symptomatic scores afer three months treatment.Results Afler the course of treatment,the total efficiency of the treatment group was 81.2%,is higher than the control group's 50.0%(P<0.05).Two groups of patients after treatment of TCM syndrome score comparison, the observation group after treatment of menstrual changes, lumbar di ministry ache, abdominal dull pain scores were lower than control group, the differences were statistically significant(all P<0.05).Conclusion The treatment of warning yang and promoting blood and Traditional Chinese Medicine combined with external application show certain therapeutic effect for tubal hydrops after actopic pregnancy and remit clinical symptoms.
引文
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[15]陆小华,马骁,王建,等.赤芍的化学成分和药理作用研究进展[J].中草药,2015,46(4):595-602.
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[18]刘德丽,包华音,刘杨.近5年黄芪化学成分及药理作用研究进展[J].食品与药品,2014,16(1):68-70.
[19]阳柳平.研究白术的化学成分及药理作用概况[J].中国医药指南,2012,10(21):607-609.
[20]张淑洁,钟凌云.厚朴化学成分及其现代药理研究进展[J].中药材,2013,36(5):838-843.
[21]段日芳.清热解毒类中药的药理作用及临床应用探讨[J].中国医药指南,2016,14(5):193-194.
[22]张好华.探讨清热解毒类中药的药理作用及应用情况[J].医药前沿,2016,6(13):378-379.
[2]王淑贞.实用妇产科科学[M].北京:人民卫生出版社,1997:582-584.
[3]郑筱萸.中药新药临床研究指导原则(试行)[M].北京:中国医药科技出版社,2002.
[4]王蕊蕊.不同中医方法治疗盆腔积液合并慢性盆腔炎的临床疗效探讨[J].实用妇科内分泌杂志(电子版),2017,4(6):32-33.
[5]张晓星,刘福彩,马玉侠,等.隔药灸脐法治疗盆腔炎性疾病后遗症[J].长春中医药大学学报,2017,33(1):112-114.
[6]李杏婵,清热解毒、活血祛瘀类中药配伍联合西医治疗慢性盆腔炎的疗效[J].实用临床医学,2015,16(7):59-61.
[7]张玉珍.中医妇科学[M].北京:中国中医药出版社,2002.
[8]杨红英,梁艳畅.保妇康栓联合头孢曲松钠、甲硝唑治疗慢性盆腔炎的临床研究[J].现代药物与临床,2015,30(6):710-713.
[9]王瑶.康妇消炎栓直肠给药治疗盆腔炎临床效果观察[J].吉林医学,2012,33(9):1857-1858.
[10]周凤悟.实用中医妇科学[M].济南:山东科学技术出版社,1985:347.
[11]肖培根.新编中药志[M].3卷.北京:化学工业出版社,2002.
[12]赵耀.桂枝的现代药理研究与临床应用浅议[J].中国中医药现代远程教育,2009,7(9):77.
[13]杜冠华,张均田.丹参现代研究概况与进展[J].医药导报,2004,23(6):355-360.
[14]许筱凰,李婷,王一涛,等.桃仁的研究进展[J].中草药,2015,46(17):2649-2655.
[15]陆小华,马骁,王建,等.赤芍的化学成分和药理作用研究进展[J].中草药,2015,46(4):595-602.
[16]马晓娟,殷惠军,陈可冀.血瘀证与炎症相关性的研究进展[J].中国中西医结合杂志,2007,27(7):669-672.
[17]刘华钢,申庆荣,刘丽敏.中药抗菌研究进展[J.时珍国医国药,2010,21(2):463-465.
[18]刘德丽,包华音,刘杨.近5年黄芪化学成分及药理作用研究进展[J].食品与药品,2014,16(1):68-70.
[19]阳柳平.研究白术的化学成分及药理作用概况[J].中国医药指南,2012,10(21):607-609.
[20]张淑洁,钟凌云.厚朴化学成分及其现代药理研究进展[J].中药材,2013,36(5):838-843.
[21]段日芳.清热解毒类中药的药理作用及临床应用探讨[J].中国医药指南,2016,14(5):193-194.
[22]张好华.探讨清热解毒类中药的药理作用及应用情况[J].医药前沿,2016,6(13):378-379.