院内热带念珠菌分离率与耐药性分析
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摘要
<正>临床上白念珠菌在分离真菌中居于首位, 但近年来非白念珠菌的感染率呈上升趋势~[1],热带念珠菌常见条件致病性真菌之一~[2],尤以广谱抗生素滥用、长期住院患者中多见,因此,了解热带念珠菌的分布及药敏性,可为临床防治热带念珠菌感染提供参考。1 资料与方法1.1 菌株来源2012年1月～2019年3月微生物实验室与细菌室从本院临床标本中分离出热带念珠菌271株。剔除同一名患者同一部位重复分离到的相同菌株。1.2 方法采用VI
引文
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[8]Silva NC,Nery JM,Dias AL.Aspartic proteinases of Candida spp.:role in patnogenicity and antifungal resistance[J].Mycoses,2014,57(1):1-11.
[9]Yang SP,Chen YY,Hsu HS,et al.A risk factor analysis of healthcare-associated fungal infections in an intensive care unit:a retrospective cohort study[J].BMC Infect Dis,2013,13:10.
[10]Cisterna R,Ezpeleta G,Telleria O,et al.Nstionwide sentinel surveillance of bloodstreamCandidainfections in 40tertiary care hospitals in Spain[J].J Clin Microbiol,2010,48(11):4200-4206.
[11]Nucci M,Queiroz-Telles F,Tobon AM,et al.Epidemiology of opportunistic fungal infections in Latin America[J].Clin Infect Dis,2010,51(5):561-570.
[12]王昊,吴大玮,韩辉,等.白念珠菌与非白念珠菌血流感染危险因素、抗菌药物应用及预后比较[J].中华传染病学杂志,2014,32(8):474-478.
[2]Silva S,Negri M,Henriques M,et al.Candida glabrata,Candida parapsilosis and Candida tropicalis:biology,epidemiology,pathogenicity and antifungal resistance[J].FEMS Microbiol Rev,2012,36(2):288-305.
[3]Clinical and Laboratory Standards Institute.Performance Standards for Antimicrobial Susceptibility Testing.Twtentieth informational supplement[S].M1O0-S20.CLSI,2010.
[4]Liu W,Tan J,Sun J et al.Invasive candidiasis in intensive care units in China:in vitro antifungal susceptibility in the China-SCAN study[J].J Antimicrob Chemother,2014,69(1):162-167.
[5]Wang H,Xiao M,Chen SC,et al.In vitro susceptibilities of yeast species to fluconazole and voriconazole as determined by the 2010 National China Hospital Invasive Fungal Surveillance Net(CHIF-NET)study[J].J Clin Microbiol,2012,50(12):3952-3959.
[6]范欣,徐英春.侵袭性热带念珠菌感染流行病学及药物敏感性[J].中国真菌学杂志,2014,9(6):368-372.
[7]Kothari A,Sagar V.Epideniology of Candida bloodstream infections in a tertiary care institute in India[J].Indian J Med Microbiol,2009,27(2):171-172.
[8]Silva NC,Nery JM,Dias AL.Aspartic proteinases of Candida spp.:role in patnogenicity and antifungal resistance[J].Mycoses,2014,57(1):1-11.
[9]Yang SP,Chen YY,Hsu HS,et al.A risk factor analysis of healthcare-associated fungal infections in an intensive care unit:a retrospective cohort study[J].BMC Infect Dis,2013,13:10.
[10]Cisterna R,Ezpeleta G,Telleria O,et al.Nstionwide sentinel surveillance of bloodstreamCandidainfections in 40tertiary care hospitals in Spain[J].J Clin Microbiol,2010,48(11):4200-4206.
[11]Nucci M,Queiroz-Telles F,Tobon AM,et al.Epidemiology of opportunistic fungal infections in Latin America[J].Clin Infect Dis,2010,51(5):561-570.
[12]王昊,吴大玮,韩辉,等.白念珠菌与非白念珠菌血流感染危险因素、抗菌药物应用及预后比较[J].中华传染病学杂志,2014,32(8):474-478.