不良妊娠史患者流产术后下腹部经皮电刺激对子宫内膜血流影响的研究
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摘要
目的探讨术后电刺激治疗育龄妇女不良妊娠患者改善子宫内膜血流的有效性。方法将44例因稽留流产、不全流产、剖宫产瘢痕妊娠术后患者随机分为两组,对照组23例行常规治疗及随访,研究组21例在常规治疗的同时行下腹部经皮电刺激的治疗,并同期随访至治疗后4个月,观察患者的症状、子宫内膜厚度和血流变化。结果治疗前研究组和对照组患者在月经量减少、腹痛发生、子宫内膜厚度和子宫内膜血流方面比较,差异无统计学意义(P>0.05);治疗后两组以上指标相比较,差异有统计学意义(P<0.05);且研究组治疗前后以上指标比较,差异也有统计学意义(P<0.05),对照组治疗前后以上指标比较,差异无统计学意义(P>0.05)。结论不良妊娠患者术后进行针对性的电刺激治疗,可有效改善其盆腔内环境及子宫内环境。
Objective To evaluate the efficacy of postoperative electrical stimulation therapy for improving the endometrial blood flow of women with unfavorable pregnancy. Methods Totally 44 women who suffered missed abortion, incomplete abortion or cesarean scar pregnancy, were divided into two groups randomly after operation. Group A accepted conventional treatment and then followed-up, Group B accepted conventional treatment and electrical stimulation therapy which can anti-inflammatory, increase endometrial thickness and improve endometrial blood flow, and followed-up at he same time. The symptoms of patients, the change of the endometrial thickness and blood flow were observed. Results Before treatment, there was no significant differences on the decreases of menstrual quantity, abdominal pain, endometrial thickness and blood flow between group A and group B(P >0.05), while after the treatment with statistically difference on above indexes(P <0.05). Those indexes also were compared in each group before and after treatment, there was no statistically difference in group A, while statistically difference in group B(P > 0.05). Conclusion Women with unfavorable pregnancy can improve their endometrial blood flow, pelvic cavity and intrauterine environment by accepting specific electrical stimulation therapy after operation to avoid unfavorable pregnancy again,which has great significance to improve the fertility of women.
Objective To evaluate the efficacy of postoperative electrical stimulation therapy for improving the endometrial blood flow of women with unfavorable pregnancy. Methods Totally 44 women who suffered missed abortion, incomplete abortion or cesarean scar pregnancy, were divided into two groups randomly after operation. Group A accepted conventional treatment and then followed-up, Group B accepted conventional treatment and electrical stimulation therapy which can anti-inflammatory, increase endometrial thickness and improve endometrial blood flow, and followed-up at he same time. The symptoms of patients, the change of the endometrial thickness and blood flow were observed. Results Before treatment, there was no significant differences on the decreases of menstrual quantity, abdominal pain, endometrial thickness and blood flow between group A and group B(P >0.05), while after the treatment with statistically difference on above indexes(P <0.05). Those indexes also were compared in each group before and after treatment, there was no statistically difference in group A, while statistically difference in group B(P > 0.05). Conclusion Women with unfavorable pregnancy can improve their endometrial blood flow, pelvic cavity and intrauterine environment by accepting specific electrical stimulation therapy after operation to avoid unfavorable pregnancy again,which has great significance to improve the fertility of women.
引文
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[2]潘萍,李予,杨冬梓,等.粒细胞集落刺激因子治疗薄型子宫内膜的研究进展[J].实用妇产科杂志,2017,33:20-23.
[3]Wang Q,Peng HL,He L,et al.The reproductive outcomes after previous cesarean scar pregnancy:a follow-up of 189 women[J].Taiwan J Obstet Gynecol,2015,54,551-553.
[4]Liang Z,Wu L,Fan L,et al.Ambient air pollution and birth defects in Haikou city,Hainan province[J].BMC Pediatrics,2014,14:283.
[5]Ashaat N,Husseiny A.Correlation between missed abortion and insertional translocation involving chromosomes 1 and 7[J].Int J Reprod Biomed,2012,10:15-22.
[6]田聪贵.300例稽留流产危险因素流行病学分析[J].中国现代药物应用,2013,7:39-40.
[7]黄莉,张莉,李洪艳,等.孕产妇不良妊娠结局危险因的巢式病例对照研究[J].中国现代医学杂志,2015,25:106-109.
[8]Mc Gowin CL,Annan RS,Quayle AJ,et a1.Persistent Mycoplasma genitalium infection of human endocervical epithelial cells elicits chronic inflammatory cytokine secretion[J].Infect Immun,2012,80:3842-3849.
[9]关少艮,麦金莲,谭伟涛,等.生物电刺激治疗对子宫内膜生长不良的疗效分析[J].国际检验医学杂志,2015,36:36-39.