手术治疗甲状腺良恶性结节的效果观察
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摘要
目的分析研究甲状腺良恶性结节通过手术治疗的方法以及治疗效果,为临床提供依据。方法选取2014年1月到2015年1月甲状腺良、恶性结节患者资料600例实施回顾性分析,其中良性结节组患者500例,恶性结节组患者100例,记录两组患者手术方法、手术效果、手术之后复发情况和不良反应发生情况,将结果进行统计学分析。结果良性结节组实施单纯肿物切除术患者50例,单侧腺叶切除术患者130例,单侧腺叶切除术+峡部切除术患者100例,单纯峡部切除术患者50例,单侧腺叶大部切除术患者120例,双侧腺叶大部切除术患者50例;恶性结节组实施一侧腺叶切除术患者30例,肿瘤切除或是腺叶部分切除术患者10例,一侧腺叶切除术+峡部切除术+对侧叶大部分切除术患者20例,全甲状腺切除术患者20例,联合根治患者20例;良性结节组患者治疗好转率明显优于恶性结节组患者(P<0.05),具有统计学意义;良性结节组患者疾病复发率明显低于恶性结节组患者(P<0.05),具有统计学意义;良性结节组患者出现甲状旁腺功能低下几率明显低于恶性结节组患者(P<0.05),具有统计学意义;两组患者喉返神经损伤几率比较没有明显的差异(P>0.05),不具有统计学意义。结论针对甲状腺良性结节患者实施手术治疗效果显著高于恶性结节患者,同时复发率以及甲状旁腺功能低下出现率显著低于恶性结节患者。
Objective The method and therapeutic effect of thyroid benign nodules were analyzed, Provide evidence for clinical practice. Methods Selected from January 2014 to January 2015 in patients with benign and malignant thyroid nodules data 600 cases were retrospectively analyzed, including 500 patients with benign nodules group, 100 cases of patients with malignant nodules group, two groups of patients with surgical method, operation effect and recurrence after surgery and adverse reactions occur, the results were statistically analyzed. Results 50 patients with benign nodules group implement simple neoplasm resection, patients with unilateral gland lobectomy in 130 cases, unilateral gland lobectomy plus isthmic resection of 100 cases of patients, 50 patients with spondylolysis resection alone, 120 patients with unilateral gland leaves much smaller, 50 patients with bilateral glands leaves much smaller; Malignant nodules group of 30 patients with implementation side gland lobectomy, 10 patients with tumor resection or glandular lobe resection, on one side of the gland lobectomy plus isthmic resection + on 20 patients with most lateral lobe resection, 20 patients with total thyroidectomy, 20 patients with combined effect a radical cure; Patients with benign nodules were significantly better than patients with malignant nodules(P<0.05), which was statistically significant. The recurrence rate of patients with benign nodules was significantly lower than that of malignant nodules(P<0.05), which was statistically significant. Patients with benign nodules were significantly lower than those in malignant nodules(P<0.05) and had statistical significance. There was no significant difference in the incidence of recurrent laryngeal nerve injury in the two groups(P>0 0.05), which was not statistically significant. Conclusion In patients with benign nodules of the thyroid gland, patients with benign nodules were significantly more effective than those with malignant nodules, and the recurrence rate and low incidence rate of parathyroid glands were significantly lower than those of malignant nodules.
Objective The method and therapeutic effect of thyroid benign nodules were analyzed, Provide evidence for clinical practice. Methods Selected from January 2014 to January 2015 in patients with benign and malignant thyroid nodules data 600 cases were retrospectively analyzed, including 500 patients with benign nodules group, 100 cases of patients with malignant nodules group, two groups of patients with surgical method, operation effect and recurrence after surgery and adverse reactions occur, the results were statistically analyzed. Results 50 patients with benign nodules group implement simple neoplasm resection, patients with unilateral gland lobectomy in 130 cases, unilateral gland lobectomy plus isthmic resection of 100 cases of patients, 50 patients with spondylolysis resection alone, 120 patients with unilateral gland leaves much smaller, 50 patients with bilateral glands leaves much smaller; Malignant nodules group of 30 patients with implementation side gland lobectomy, 10 patients with tumor resection or glandular lobe resection, on one side of the gland lobectomy plus isthmic resection + on 20 patients with most lateral lobe resection, 20 patients with total thyroidectomy, 20 patients with combined effect a radical cure; Patients with benign nodules were significantly better than patients with malignant nodules(P<0.05), which was statistically significant. The recurrence rate of patients with benign nodules was significantly lower than that of malignant nodules(P<0.05), which was statistically significant. Patients with benign nodules were significantly lower than those in malignant nodules(P<0.05) and had statistical significance. There was no significant difference in the incidence of recurrent laryngeal nerve injury in the two groups(P>0 0.05), which was not statistically significant. Conclusion In patients with benign nodules of the thyroid gland, patients with benign nodules were significantly more effective than those with malignant nodules, and the recurrence rate and low incidence rate of parathyroid glands were significantly lower than those of malignant nodules.
引文
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[6]张渊,江泉,陈剑,等.实时超声造影在甲状腺乳头状癌诊断中的应用研究[J].中国临床医学影像杂志,2011,2(11):16.
[2]谭广谋,廖卫国,陈伟泉,等.超声引导穿刺组织病理学检查对甲状腺结节诊断价值的探讨[J].中华肿瘤防治杂志,2014,6(6):902-904.
[3]魏小丽,于晓玲,郝晓云,等.甲状腺结节超声引导下穿刺活检的临床价值[J].军医进修学院学报,2012,13(5):1226.
[4]Simon D.Duek,David Goldenberg,Shai Linn,et al.The Role of Fine-Needle Aspiration and Intraoperative Frozen Section in the Surgical Management of Solitary Thyroid Nodules[J].Surgery Today,2012,6(10):33.
[5]马姣姣,丁红,徐本华,等.甲状腺结节超声诊断价值的探讨及最佳量化评分点的探寻[J].中华医学超声杂志(电子版).2013,20(6):911-912.
[6]张渊,江泉,陈剑,等.实时超声造影在甲状腺乳头状癌诊断中的应用研究[J].中国临床医学影像杂志,2011,2(11):16.