由科研开发的综合化学实验:三乙胺/水杨酸新型低温共熔溶剂的合成、表征与性能
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摘要
结合科研实践,设计合成了三乙胺/水杨酸新型低温共熔溶剂[TEA][OHBA]_2,采用红外光谱和核磁共振氢谱对其结构进行了确证,测定了其理化性能(热稳定性、荧光性、黏度和密度),并揭示了[TEA][OHBA]_2的形成及其特性源于三乙胺与水杨酸分子间形成了氢键的机理。低温共熔溶剂[TEA][OHBA]_2在环境分析和医药领域具有广阔的应用前景。该实验移植于科研,集化学合成、结构表征、性能测试于一体,具有前沿性、交叉性、综合性、应用性、研究性。开设该实验能够提高综合化学实验水平和学生实验兴趣,有利于学生创新意识的培养和综合能力的提高。
On the basis of scientific research practices, the novel deep eutectic solvent triethylamine/salicylic acid, [TEA][OHBA]_2, was designed and synthesized. The structure of [TEA][OHBA]_2 was confirmed by using infrared spectroscopy, and ~1H nuclear magnetic resonance spectroscopy. The physical and chemical properties, including the thermal stability, fluorescence, viscosity, and density, were determined. The formation of [TEA][OHBA]_2 mainly depends on hydrogen bonds between TEA and OHBA. [TEA][OHBA]_2 has broad application potential in environmental analysis and medical fields. This experiment is based on previous scientific research, and involves integrated chemical synthesis, structural characterization, and performance testing. Therefore, this applied and research-based work is advanced, cross-disciplinary, and comprehensive. The introduction of the experiment can improve the level of comprehensive experimental knowledge and interest for students, and it is conducive to cultivating the students' innovation, and improving their abilities.
On the basis of scientific research practices, the novel deep eutectic solvent triethylamine/salicylic acid, [TEA][OHBA]_2, was designed and synthesized. The structure of [TEA][OHBA]_2 was confirmed by using infrared spectroscopy, and ~1H nuclear magnetic resonance spectroscopy. The physical and chemical properties, including the thermal stability, fluorescence, viscosity, and density, were determined. The formation of [TEA][OHBA]_2 mainly depends on hydrogen bonds between TEA and OHBA. [TEA][OHBA]_2 has broad application potential in environmental analysis and medical fields. This experiment is based on previous scientific research, and involves integrated chemical synthesis, structural characterization, and performance testing. Therefore, this applied and research-based work is advanced, cross-disciplinary, and comprehensive. The introduction of the experiment can improve the level of comprehensive experimental knowledge and interest for students, and it is conducive to cultivating the students' innovation, and improving their abilities.
引文
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[3] 曹小华,喻国贞,雷艳红,等.化学教育,2009,30(11):15-16
[4] 魏莹,许辉.化学教育,2014,35(12):37-41
[5] 贺德华,师磊,麻英.实验技术与管理,2006,23(11):15-17
[6] 韦露,樊友军.化学通报,2011,74(4):333-339
[7] Andrew P,David B,Glen C,et al.Journal of the American Chemical Society,2004,126(29):9142-9147
[8] Emma L,Andrew P,Karl S.Chemical Reviews,2014,114(21):11060-11082
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[10] 韦露,樊友军.化学通报,2011,74(4):333-339
[11] 于振云.化工中间体,2003(21):27-32
[12] 孟雪娇,邸昆,丁国华.中国农学通报,2010,26(15):207-214
[13] 孙艳涛,邱笑阳,苏斌,等.科教文汇,2018(2):184-185
[14] 徐彦芹,杨瑶,朱小会,等.实验技术与管理,2016,33(9):50-52
[15] 杨斌,程杰,李国芳.现代制造技术与装备,2014(2):52-52
[16] Zhu W,Wang C,Li H,et al.Green Chemistry,2015,17(4):2464-2472
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[19] 张盈盈,陆小华,冯新,等.化学进展,2013,25(6):881-892
[20] 洪满水,郭金全,黄基钊.塑料工业,1982(2):49-50