实验大鼠负重装置的研制
|
摘要
目的研制既符合大鼠躯干结构,又不影响大鼠心肺功能的试验大鼠负重装置;并且能方便负重负荷装载和质量的调整。方法选取柔软舒适的布料,根据SD大鼠躯干各部位的周径,设计出符合躯干结构的负重装置;采用化学定量分析法测量大鼠的呼吸速率,评定负重装置对大鼠心肺功能是否有影响。结果制作出相对简略未外观美化处理的负重装置;经分析有无配戴装置下的呼吸速率数据,表明在实验误差允许范围内不影响大鼠心肺功能。结论装置将为研究负重的质量不同与骨骼肌损伤程度的关系,及为确定最佳的负重质量等提供一个简便、实用的负重装置;也为骨骼肌损伤研究增加一个可探索研究的负重变量因素。
Objective To develop a weight-bearing device that conforms to the body structure of rats without affecting their cardio-pulmonary function and also is easy to be loaded and adjusted in weights. Methods A weightbearing device was developed using comfortable and soft fabrics according to the diameters of various body parts in rats. The respiration rate of rats was measured using chemical quantitative analysis to assess the effect of weightbearing devices on the rats' cardio-pulmonary function. Results A simple weight-bearing device without any beautification was developed. The respiration rates of rats were analyzed with and without the weight-bearing device, which showed that this device did not affect the cardio-pulmonary function of rats within the error range. Conclusion This device is very simple and practical and can be used in exploring the relationship between different weights and the muscle damage and identifying the optimal weight. Also, it provides another variable worthy of research in the study of muscle damage.
Objective To develop a weight-bearing device that conforms to the body structure of rats without affecting their cardio-pulmonary function and also is easy to be loaded and adjusted in weights. Methods A weightbearing device was developed using comfortable and soft fabrics according to the diameters of various body parts in rats. The respiration rate of rats was measured using chemical quantitative analysis to assess the effect of weightbearing devices on the rats' cardio-pulmonary function. Results A simple weight-bearing device without any beautification was developed. The respiration rates of rats were analyzed with and without the weight-bearing device, which showed that this device did not affect the cardio-pulmonary function of rats within the error range. Conclusion This device is very simple and practical and can be used in exploring the relationship between different weights and the muscle damage and identifying the optimal weight. Also, it provides another variable worthy of research in the study of muscle damage.
引文
[1]闫万军.负重跑训练改善老龄大鼠肌肉丢失的效果与机理[D].石家庄:河北师范大学,2008:40-44.
[2]闫万军,赵斌,刘丰彬,等.负重跑训练对老龄大鼠肌肉丢失的影响[J].中国体育科技,2009,45(4):120-124.
[3]张胜年,陆爱云.骨骼肌运动损伤实验研究中的动物模刑[J].中国运动学杂志,2000,19(2):185-188.
[4]刘迅雷.6周递增负荷训练大鼠骨骼肌IGF-I及血清GH,IGF-I水平影响的研究[J].山西师大体育学院学报,2003,18(1):75-76.
[5]朱晓兰,杨辉.我国青年田径运动员不同载荷下足部三维特征的研究[J].北京体育大学学报,2008,31(12):1649-1650.
[6]Kraemer WJ,Ratamess NA,French DN.Resistance training for health and performance[J].Curr Sports Med Rep,2002,1(3):165-171.
[7]王峰,王彦伟,赵斌,等.负重训练对老龄大鼠骨生物力学性能的影响[J].天津体育学院学报,2011,26(5):440-443.
[8]黄诚胤,李国泰.不同负重强度运动对去势大鼠股骨生物学指标的影响[J].武汉体育学院学报,2011,45(9):46-49.
[9]赵晓明,王航平,王廷华.不同负重游泳训练对大鼠肾上腺BDNF和trkB表达的影响[J].四川解剖学杂志,2011,19(4):17-19.
[10]王静,苏有存,卢健.负重爬梯训练对大鼠胖肠肌IGF-Ⅰ、IGF-IEa、MGF和MSTN基因表达的影响[J].山东体育学院学报,2011,27(5):55-58.
[11]李海鹏,卢健,陈彩珍.SARCOYENIA机制研究进展[J].体育科学,2007,27(11):66-69.
[2]闫万军,赵斌,刘丰彬,等.负重跑训练对老龄大鼠肌肉丢失的影响[J].中国体育科技,2009,45(4):120-124.
[3]张胜年,陆爱云.骨骼肌运动损伤实验研究中的动物模刑[J].中国运动学杂志,2000,19(2):185-188.
[4]刘迅雷.6周递增负荷训练大鼠骨骼肌IGF-I及血清GH,IGF-I水平影响的研究[J].山西师大体育学院学报,2003,18(1):75-76.
[5]朱晓兰,杨辉.我国青年田径运动员不同载荷下足部三维特征的研究[J].北京体育大学学报,2008,31(12):1649-1650.
[6]Kraemer WJ,Ratamess NA,French DN.Resistance training for health and performance[J].Curr Sports Med Rep,2002,1(3):165-171.
[7]王峰,王彦伟,赵斌,等.负重训练对老龄大鼠骨生物力学性能的影响[J].天津体育学院学报,2011,26(5):440-443.
[8]黄诚胤,李国泰.不同负重强度运动对去势大鼠股骨生物学指标的影响[J].武汉体育学院学报,2011,45(9):46-49.
[9]赵晓明,王航平,王廷华.不同负重游泳训练对大鼠肾上腺BDNF和trkB表达的影响[J].四川解剖学杂志,2011,19(4):17-19.
[10]王静,苏有存,卢健.负重爬梯训练对大鼠胖肠肌IGF-Ⅰ、IGF-IEa、MGF和MSTN基因表达的影响[J].山东体育学院学报,2011,27(5):55-58.
[11]李海鹏,卢健,陈彩珍.SARCOYENIA机制研究进展[J].体育科学,2007,27(11):66-69.