农村居民脂肪肝患病情况及影响因素分析
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摘要
目的分析农村居民脂肪肝的患病情况,探讨其影响因素,为针对农村居民脂肪肝的防治提供科学依据。方法选取2015年某卫生院健康体检的1 728例农村居民,经B超明确诊断为脂肪肝患者479例,分析不同特征居民脂肪肝的患病情况,并应用单因素和多元Logistic回归模型方法探讨农村居民脂肪肝患病的影响因素。结果所调查农村居民总脂肪肝患病率为27.7%,其中男27.1%,女28.4%。多因素Logistic回归分析表明,年龄、高血压、糖尿病、体重指数(BMI)、空腹血糖(FPG)、总胆固醇(TC)、甘油三酯(TG)、低密度脂蛋白胆固醇(LDL-C)是农村居民脂肪肝患病的危险因素(P<0.05),高密度脂蛋白胆固醇(HDL-C)为其保护因素,即HDL-C越高,脂肪肝的患病危险性越低(P<0.05)。结论农村居民脂肪肝的患病率较高,年龄、高血压、糖尿病、BMI及高脂血症与脂肪肝的患病密切相关。
Objective To analyze the prevalence of fatty liver in rural residents and investigate its influencing factors,and to provide the basis of prevention and treatment for fatty liver.Methods During 2015,1728 rural residents were chosen from a health examination,in which 479 fatty liver cases were diagnosed by type-B ultrasonic test,the prevalence of fatty liver among residents with different characteristics were analyzed,and the influence factors of fatty liver disease were explored by single factor analysis and logistic regression model.Results The total prevalence rate of fatty liver in rural residents was 27.7%,among which 27.1% were male and 28.4% were female.Multivariate logistic regression analysis showed that age,hypertension,diabetes,body mass index(BMI),fasting blood glucose(FPG),total cholesterol(TC),Triglyceride(TG)and low density lipoprotein cholesterol(LDL-C)were the risk factors of fatty liver among the rural residents(P<0.05),high density lipoprotein cholesterol(HDL-C)was the protective factor,that is,the higher the HDL-C,the lower the risk of fatty liver(P<0.05).Conclusions The prevalence rate of fatty liver in rural residents is high,and the age,hypertension,diabetes,BMI and hyperlipidemia are closely related to the prevalence of fatty liver disease.
Objective To analyze the prevalence of fatty liver in rural residents and investigate its influencing factors,and to provide the basis of prevention and treatment for fatty liver.Methods During 2015,1728 rural residents were chosen from a health examination,in which 479 fatty liver cases were diagnosed by type-B ultrasonic test,the prevalence of fatty liver among residents with different characteristics were analyzed,and the influence factors of fatty liver disease were explored by single factor analysis and logistic regression model.Results The total prevalence rate of fatty liver in rural residents was 27.7%,among which 27.1% were male and 28.4% were female.Multivariate logistic regression analysis showed that age,hypertension,diabetes,body mass index(BMI),fasting blood glucose(FPG),total cholesterol(TC),Triglyceride(TG)and low density lipoprotein cholesterol(LDL-C)were the risk factors of fatty liver among the rural residents(P<0.05),high density lipoprotein cholesterol(HDL-C)was the protective factor,that is,the higher the HDL-C,the lower the risk of fatty liver(P<0.05).Conclusions The prevalence rate of fatty liver in rural residents is high,and the age,hypertension,diabetes,BMI and hyperlipidemia are closely related to the prevalence of fatty liver disease.
引文
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[9]姜懿华,金灿道,张舜.海军飞行人员脂肪肝与年龄的相关性分析[J].海军医学杂志,2010,31(3):237-238
[10]郑盛,尤丽英,唐映梅,等.体检人群血尿酸水平与非酒精性脂肪性肝病的相关性研究[J].中国全科医学,2012,15(8):844-847
[11]俞小忠,夏燕,董敏,等.脂肪肝患者体重指数与胰岛素抵抗及肝酶关系研究[J].医学研究生学报,2011,24(8):843-846
[12]侯桂侠,张素娟,王铭,等.老年脂肪肝患病危险因素病例对照研究[J].职业与健康,2016,32(1):88-90
[13]成昌盛,龚秀琴,黄美.1 379例脂肪肝患者的相关影响因素分析[J].护理学报,2013,20(10B):29-32
[14]Ercin CN,Dogru T,Genc H,et al.Insulin resistance but not visceral adiposity index is associated with liver fibrosis in nondiabetic subjects with nonalcoholic fatty liver disease[J].Metab Syndr Relat Disord,2015,13(7):319-325
[15]Tai FWD,Syn WK,Alazawi W.Practical approach to non-alcoholic fatty liver disease in patients with diabetes[J].Diabet Med,2015,32(9):1121-33
[16]Bhatt HB,Smith RJ.Fatty liver disease in diabetes mellitus[J].Hepatobiliary Surg Nutr,2015,4(2):101-108
[2]中华医学会肝脏病学分会脂肪肝和酒精性肝病学组.非酒精性脂肪肝诊疗指南[J].中华肝脏病杂志,2006,14(2):161-162
[3]余霞玲,傅迎春,文育锋.北京某化工企业职工脂肪肝患病情况及其影响因素分析[J].中华疾病控制杂志,2015,19(8):803-805
[4]魏颖,赫英英,厉玉婷,等.基于女性健康体检人群的脂肪肝患病情况及膳食影响因素研究[J].中国卫生事业管理,2014,(6):471-475
[5]李金萍,丁媛媛,王炳元,等.东北地区城市脂肪肝的患病率及其危险因素的流行病学调查[J].胃肠学和肝病学,2011,20(7):617-623
[6]郑剑勇,陈佩,谢建妙.社区居民脂肪肝患病率及影响因素分析[J].中国预防医学杂志,2011,12(2):152-154
[7]马金香,周永健,陈平雁,等.广东省农村社区居民脂肪肝流行病学调查[J].中国公共卫生,2007,23(7):874-876
[8]韩涛,张艳男,荣胜忠,等.哈尔滨市区居民脂肪肝患病率与危险因素分析[J].哈尔滨医科大学学报,2013,47(4):363-366
[9]姜懿华,金灿道,张舜.海军飞行人员脂肪肝与年龄的相关性分析[J].海军医学杂志,2010,31(3):237-238
[10]郑盛,尤丽英,唐映梅,等.体检人群血尿酸水平与非酒精性脂肪性肝病的相关性研究[J].中国全科医学,2012,15(8):844-847
[11]俞小忠,夏燕,董敏,等.脂肪肝患者体重指数与胰岛素抵抗及肝酶关系研究[J].医学研究生学报,2011,24(8):843-846
[12]侯桂侠,张素娟,王铭,等.老年脂肪肝患病危险因素病例对照研究[J].职业与健康,2016,32(1):88-90
[13]成昌盛,龚秀琴,黄美.1 379例脂肪肝患者的相关影响因素分析[J].护理学报,2013,20(10B):29-32
[14]Ercin CN,Dogru T,Genc H,et al.Insulin resistance but not visceral adiposity index is associated with liver fibrosis in nondiabetic subjects with nonalcoholic fatty liver disease[J].Metab Syndr Relat Disord,2015,13(7):319-325
[15]Tai FWD,Syn WK,Alazawi W.Practical approach to non-alcoholic fatty liver disease in patients with diabetes[J].Diabet Med,2015,32(9):1121-33
[16]Bhatt HB,Smith RJ.Fatty liver disease in diabetes mellitus[J].Hepatobiliary Surg Nutr,2015,4(2):101-108