序贯性血液净化在治疗中毒合并多器官功能障碍综合征的临床疗效观察
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摘要
目的分析序贯性血液净化在治疗中毒合并多器官功能障碍综合征的应用价值。方法选取2012年1月—2017年9月本院收治的中毒并多器官功能障碍综合征患者42例,对照组21例,给予患者进行常规治疗,实验组给予患者进行序贯性血液净化治疗,对比两组患者的指标。结果实验组昏迷时间是(6.84±1.13)h,低于对照组(11.15±2.17)h,机械通气时间是(22.56±5.41)h,低于对照组(31.4±5.18)h,住院时间(13.5±3.19)d,小于对照组(25.25±4.14)d,差异具有统计学意义(P<0.05)。实验组CRP、Ser低于对照组,差异具有统计学意义(P<0.05);实验组病死率为9.5%,低于对照组死亡率23.8%,差异具有统计学意义。结论在给予患者进行序贯性血液净化治疗,可以提高治疗成功率,降低死亡率,值得在临床上进行推广使用。
Objective To analyze the value of sequential blood purification in the treatment of poisoning complicated with multiple organ dysfunction syndrome( MODS). Methods 42 cases of intoxication and multiple organ dysfunction syndrome in our hospital from January 2012 to September 2017 were selected,and 21 cases in the control group. The patients were given routine treatment,and the experimental group was given sequential blood purification treatment.Results The experimental group coma time( 6.84±1.13) H is lower than that of the control group( 11.15± 2. 17) h,mechanical ventilation time is( 22. 56 ± 5. 41) h,lower than that of the control group( 31.4±5.18) h,hospitalization time( 13.5±3.19) d less than that of the control group( 25.25± 4.14) d,the difference was statistically significant( P < 0. 05). Conclusions Sequential blood purification treatment can improve the success rate of treatment and reduce the mortality rate. It is worth popularizing in clinical practice.
Objective To analyze the value of sequential blood purification in the treatment of poisoning complicated with multiple organ dysfunction syndrome( MODS). Methods 42 cases of intoxication and multiple organ dysfunction syndrome in our hospital from January 2012 to September 2017 were selected,and 21 cases in the control group. The patients were given routine treatment,and the experimental group was given sequential blood purification treatment.Results The experimental group coma time( 6.84±1.13) H is lower than that of the control group( 11.15± 2. 17) h,mechanical ventilation time is( 22. 56 ± 5. 41) h,lower than that of the control group( 31.4±5.18) h,hospitalization time( 13.5±3.19) d less than that of the control group( 25.25± 4.14) d,the difference was statistically significant( P < 0. 05). Conclusions Sequential blood purification treatment can improve the success rate of treatment and reduce the mortality rate. It is worth popularizing in clinical practice.
引文
[1]陈国涛,费沛,张庆红,等.序贯性血液净化技术抢救急性中毒致多器官功能障碍综合征30例临床观察[J].中国美容医学杂志,2012,21(18):255-256.
[2]侯景玉,吴畏,陈希妍,等.序贯性血液净化治疗急性重度有机磷农药中毒并发多器官功能障碍综合征疗效观察[J].新乡医学院学报,2016,33(2):126-129.
[3]王旭,董斌,李弢,等.序贯性血液净化治疗蜂中毒并多器官功能障碍综合征疗效分析[J].中华实用儿科临床杂志,2015,30(6):442-444.
[4]李川,何群鹏,谢红浪,等.高容量血液滤过治疗热射病伴多器官功能障碍综合征的临床疗效分析[J].肾脏病与透析肾移植杂志,2012,21(1):35-40.
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[7]白云芬.CRRT治疗1例野生菌中毒多器官功能障碍综合征患者护理体会[J].内蒙古中医药,2016,35(1):175-176.
[8]杨胜,葛燕萍,张冬惠,等.连续性血液净化并强化目标控制温度管理救治热射病患者的临床观察[J].中国中西医结合急救杂志,2017,24(4):409-414.
[9]罗彩云,王翔凤.糖尿病酮症酸中毒合并多器官功能障碍综合征病人的急救护理[J].全科护理,2013,11(21):1982-1983.
[10]郭伟.急救护理用于糖尿病酮症酸中毒合并多器官功能障碍综合征患者的临床探讨[J].糖尿病新世界,2015,35(18):6-8.
[11]刘子梦,袁睿,谢媛,等.急性砷化氢中毒合并多器官功能障碍综合征24例的早期血生化分析[J].中华灾害救援医学,2016,4(3):156-158.
[12]郑艺花,罗志锋,马井生,等.联合血液净化治疗急性鱼胆中毒合并多器官功能障碍综合征的效果[J].国际移植与血液净化杂志,2015,13(1):16-18.
[13]胡峰,张贺,陈洁,等.序贯性血液净化治疗中毒并多器官功能障碍综合征[J].实用医药杂志,2012,29(6):483-485.
[14]赵欢,石雪,王爱平,等.糖尿病高渗性昏迷合并酮症酸中毒致急性重症胰腺炎及多器官功能障碍综合征1例报告及文献复习[J].中国实验诊断学,2016(1):143-144.
[15]梁艳斌,胡家昌,王利民,等.重度有机磷农药中毒致多器官功能障碍综合症死亡因素的探讨[J].现代生物医学进展,2015,15(7):1317-1320.
[2]侯景玉,吴畏,陈希妍,等.序贯性血液净化治疗急性重度有机磷农药中毒并发多器官功能障碍综合征疗效观察[J].新乡医学院学报,2016,33(2):126-129.
[3]王旭,董斌,李弢,等.序贯性血液净化治疗蜂中毒并多器官功能障碍综合征疗效分析[J].中华实用儿科临床杂志,2015,30(6):442-444.
[4]李川,何群鹏,谢红浪,等.高容量血液滤过治疗热射病伴多器官功能障碍综合征的临床疗效分析[J].肾脏病与透析肾移植杂志,2012,21(1):35-40.
[5]李诚,朱亚梅,张静,等.15例连续性血液净化治疗重症急性胰腺炎合并多器官功能障碍综合征的疗效观察与护理[J].实用临床医药杂志,2013,17(20):1-4.
[6]程文涛.连续血液净化治疗ICU多器官功能障碍综合征患者的疗效[J].实用临床医药杂志,2015,19(3):136-137.
[7]白云芬.CRRT治疗1例野生菌中毒多器官功能障碍综合征患者护理体会[J].内蒙古中医药,2016,35(1):175-176.
[8]杨胜,葛燕萍,张冬惠,等.连续性血液净化并强化目标控制温度管理救治热射病患者的临床观察[J].中国中西医结合急救杂志,2017,24(4):409-414.
[9]罗彩云,王翔凤.糖尿病酮症酸中毒合并多器官功能障碍综合征病人的急救护理[J].全科护理,2013,11(21):1982-1983.
[10]郭伟.急救护理用于糖尿病酮症酸中毒合并多器官功能障碍综合征患者的临床探讨[J].糖尿病新世界,2015,35(18):6-8.
[11]刘子梦,袁睿,谢媛,等.急性砷化氢中毒合并多器官功能障碍综合征24例的早期血生化分析[J].中华灾害救援医学,2016,4(3):156-158.
[12]郑艺花,罗志锋,马井生,等.联合血液净化治疗急性鱼胆中毒合并多器官功能障碍综合征的效果[J].国际移植与血液净化杂志,2015,13(1):16-18.
[13]胡峰,张贺,陈洁,等.序贯性血液净化治疗中毒并多器官功能障碍综合征[J].实用医药杂志,2012,29(6):483-485.
[14]赵欢,石雪,王爱平,等.糖尿病高渗性昏迷合并酮症酸中毒致急性重症胰腺炎及多器官功能障碍综合征1例报告及文献复习[J].中国实验诊断学,2016(1):143-144.
[15]梁艳斌,胡家昌,王利民,等.重度有机磷农药中毒致多器官功能障碍综合症死亡因素的探讨[J].现代生物医学进展,2015,15(7):1317-1320.