高效液相色谱—串联质谱法检测鸡蛋中氟虫腈及其代谢物的残留

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英文篇名：Determination of Fipronil and Its Metabolites Residue in Egg by HPLC/MS/MS 作者：龚勇 ; 朴秀英 ; 孙丰收 ; 崔凯 ; 廖先骏 ; 李富根 英文作者：Gong Yong;Piao Xiuying;Liao Xianjun;Li Fugen;Sun Fengshou;Cui Kai;Institute for the Control of Agrochemicals,Ministry of Agriculture;Center for Pesticide Environmental Toxicology,SDAU;Institute of quality safety and nutrition of agricultural products,Jiangsu Academy of Agricultural Sciences; 关键词：鸡蛋 ; 氟虫腈 ; 代谢物 ; 残留 ; GPC ; 液相色谱-串联质谱 英文关键词：egg;;fipronil;;metabolites;;residue;;GPC;;HPLC/MS/MS 中文刊名：NYKG 英文刊名：Pesticide Science and Administration 机构：农业部农药检定所;山东农业大学环境毒理研究中心;江苏省农业科学院农产品质量安全与营养研究所; 出版日期：2018-03-15 出版单位：农药科学与管理 年：2018 期：v.39;No.273 语种：中文; 页：NYKG201803015 页数：5 CN：03 ISSN：11-2678/S 分类号：58-62

摘要

建立氟虫腈及其代谢物(氟甲腈、氟虫腈砜、氟虫腈亚砜)在鸡蛋中的残留分析方法。采用乙酸乙酯-环己烷(1:1)提取,GPC净化,通过高效液相色谱-串联质谱进行测定。本方法添加回收率在80.7%～114.3%之间,相对标准偏差在3.4%～15.9%之间,定量限为0.002mg/kg。本方法净化效果好,准确度高,能适用于干扰较强的基质情况。
        The method for the determination of fipronil and its metabolite( fipronil desulfinyl,fipronil sulfone and fipronil sulfide) in egg was established. The samples were extracted with ethyl acetate-cyclohexane(1 : 1), purified by GPC and finally determined by HPLC/MS/MS. The recoveries of 80. 7% to 114. 3%, the variation coefficients of 3. 4% to 15. 9% and the detection limit of 0. 002 mg/kg were obtained for the method. This method, with good cleaning effect and high accuracy, is applicable of matrix with strong interference.

引文

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