肺力咳合剂治疗小儿毛细支气管炎的临床效果研究
摘要
目的探讨肺力咳合剂治疗小儿毛细支气管炎的临床效果。方法选取2016年1月至2017年2月34例小儿毛细支气管炎患儿并分组。对照组采用常规的药物进行治疗,肺力咳组在对照组基础上给予肺力咳合剂治疗。比较两组小儿毛细支气管炎缓解率;气喘、痰多、咳嗽、哮鸣音消失时间;干预前后患儿免疫状态;治疗不良反应发生率。结果肺力咳组小儿毛细支气管炎缓解率16(94.12%)高于照组12(70.59%)(P<0.05);肺力咳组气喘、痰多、咳嗽、哮鸣音消失时间(3.25±1.41)d、(5.25±2.61)d、(5.14±1.21)d、(6.14±1.61)d短于对照组(4.12±2.24)d、(7.12±3.57)d、(6.53±2.59)d、(7.12±2.57)d(P<0.05)。干预前两组免疫状态相近,差异无统计学意义;干预后肺力咳组免疫状态优于对照组(P<0.05)。两组治疗不良反应发生率差异无统计学意义。其中,对照组有1例头晕、1例呕吐和1例腹泻,发生率17.65%;肺力咳组有1例头晕、1例呕吐和1例腹泻,发生率17.65%。结论肺力咳合剂治疗小儿毛细支气管炎的临床效果确切,可有效改善免疫状态,加速临床症状消失,缩短疗程,无影响副作用,安全性高,值得推广。
引文
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[9]张剑,陈鹤.不同剂量布地奈德混悬液雾化吸入联合肺力咳合剂口服治疗小儿哮喘临床对照研究[J].中国药业,2016,25(24):50-53.
[10]肖韵,王建刚.肺力咳合剂治疗小儿急性支气管炎的临床观察[J].中国医药指南,2017,15(19):187-188.
[2] Pickles Raymond J, DeVincenzo John P. Respiratory syncytial virus(RSV)and its propensity for causing bronchiolitis[J]. Journal of Pathology:Journal of the Pathological Society of Great Britain and Ireland, 2015,235(2):266-276.
[3]励爱,贺登科.布地奈德联合肺力咳治疗小儿哮喘[J].中国实验方剂学杂志,2014,20(24):207-209.
[4] Moreno-Solis Gloria, Fernandez-Gutierrez Fernando,Torres-Borrego Javier, et al. Low serum 25-hydroxyvitamin D levels and bronchiolitis severity in Spanish infants[J]. European journal of pediatrics,2015,174(3):365-372.
[5]袁立.布地奈德联合肺力咳治疗小儿哮喘疗效观察与分析[J].中国继续医学教育,2015,25(18):220-221.
[6]刘立华,刘立鑫.布地奈德混悬液联合肺力咳糖浆治疗小儿咳嗽变异性哮喘的可行性[J].大家健康,2015,24(8):132-133.
[7] Towe Christopher, Ogborn A Chester, Ferkol Thomas,et al. Bronchiolitis obliterans syndrome is not specific for bronchiolitis obliterans in pediatric lung transplant[J]. The Journal of heart and lung transplantation:the official publication of the International Society for Heart Transplantation, 2015,34(4):516-521.
[8]叶再青,杨玲利,周绍珍,等.肺力咳合剂与宣肺止嗽合剂治疗小儿支气管炎痰热壅肺型的临床疗效观察[J].中国药师,2016,19(5):933-935.
[9]张剑,陈鹤.不同剂量布地奈德混悬液雾化吸入联合肺力咳合剂口服治疗小儿哮喘临床对照研究[J].中国药业,2016,25(24):50-53.
[10]肖韵,王建刚.肺力咳合剂治疗小儿急性支气管炎的临床观察[J].中国医药指南,2017,15(19):187-188.