2010—2013年南京市成年居民代谢综合征患病情况及流行特征
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摘要
目的了解南京市成年居民代谢综合征(MS)的患病情况以及流行特征。方法 2010—2013年,采用多阶段分层与人口成比例的整群随机抽样的方法,共调查南京市成年居民4918人。对调查对象进行问卷调查、体格检查和实验室检查,收集调查对象的基本情况、个人健康情况以及身高、体重、腰围、血压、空腹血糖、总胆固醇、甘油三酯、高密度脂蛋白胆固醇等相关指标。MS患者的筛查采用2009年国际联合暂定声明(JIS)诊断标准。结果 4918名调查对象中有1627人患MS,粗患病率为33.1%,年龄标化患病率为26.3%,男性MS年龄标化患病率为29.0%,女性为24.8%,不同性别之间的年龄标化患病率差异无统计学意义(χ~2=1.352,P=0.245)。不同年龄段(χ~2=132.557,P<0.001)、职业(χ~2=87.572,P<0.001)、文化程度(χ~2=26.077,P<0.001)的调查对象MS患病率间差异均有统计学意义。有高血压(χ~2=26.582,P<0.001)、糖尿病(χ~2=16.013,P<0.001)家族史的调查对象MS患病率更高。结论 2010—2013年南京市成年居民代谢综合征患病率较高。
OBJECTIVE To understand the prevalence and epidemic characteristics of metabolic syndrome(MS) among adult residents in Nanjing City. METHODS In 2010-2013, a total of 4918 adult residents in Nanjing City were surveyed using a multi-stage stratification and population proportional clustering random sampling method.Questionnaires, physical examinations and laboratory examinations were conducted to collect the basic conditions, health history of the subjects and related indicators including height, weight, waist circumference, blood pressure, fasting blood glucose, total cholesterol, triglycerides, high-density lipoprotein cholesterol, etc. The 2009 International Joint Interim Statement(JIS) was used to filter patients with metabolic syndrome. RESULTS Among the 4918 surveyed subjects, 1627 were MS, with a crude prevalence rate of 33.1% and an age-standardized prevalence rate of 26.3%, the standardized prevalence rate of MS was 29.0% in males and 24.8% in females. Age-standardized prevalence rates between different genders had no significant statistical difference(χ~2=1.352,P=0.245). There were significant statistical differences between the crude prevalence rate of MS among subjects of different ages(χ~2=132.557,P<0.001), occupations(χ~2=87.572,P<0.001)and educational level(χ~2=26.077,P<0.001). Patients with a family history of hypertension(χ~2=26.582,P<0.001) and a family history of diabetes(χ~2=16.013,P<0.001)had a higher prevalence of MS. CONCLUSION The prevalence of metabolic syndrome in adult residents in Nanjing City in 2010-2013 was relatively high.
OBJECTIVE To understand the prevalence and epidemic characteristics of metabolic syndrome(MS) among adult residents in Nanjing City. METHODS In 2010-2013, a total of 4918 adult residents in Nanjing City were surveyed using a multi-stage stratification and population proportional clustering random sampling method.Questionnaires, physical examinations and laboratory examinations were conducted to collect the basic conditions, health history of the subjects and related indicators including height, weight, waist circumference, blood pressure, fasting blood glucose, total cholesterol, triglycerides, high-density lipoprotein cholesterol, etc. The 2009 International Joint Interim Statement(JIS) was used to filter patients with metabolic syndrome. RESULTS Among the 4918 surveyed subjects, 1627 were MS, with a crude prevalence rate of 33.1% and an age-standardized prevalence rate of 26.3%, the standardized prevalence rate of MS was 29.0% in males and 24.8% in females. Age-standardized prevalence rates between different genders had no significant statistical difference(χ~2=1.352,P=0.245). There were significant statistical differences between the crude prevalence rate of MS among subjects of different ages(χ~2=132.557,P<0.001), occupations(χ~2=87.572,P<0.001)and educational level(χ~2=26.077,P<0.001). Patients with a family history of hypertension(χ~2=26.582,P<0.001) and a family history of diabetes(χ~2=16.013,P<0.001)had a higher prevalence of MS. CONCLUSION The prevalence of metabolic syndrome in adult residents in Nanjing City in 2010-2013 was relatively high.
引文
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[12] 丁贤彬,毛德强,沈卓之,等. 重庆市城市居民代谢综合征患病率及影响因素分析[J]. 华南预防医学,2017,43 (4):301-305.
[13] 宋雅珊,王明军,叶旭东,等. 广西地区成年人代谢综合征患病率横断面调查[J]. 临床肾脏病杂志,2017,17 (5):271-275.
[14] 洪汝丹,陆林,杨永芳,等. 云南省6县(区)常住居民代谢综合征患病率及其影响因素分析[J]. 中国慢性病预防与控制,2013,21 (5):530-535.
[15] 董莹,王馨,张林峰,等. 新疆地区≥35岁人群代谢综合征患病率情况调查[J]. 中华疾病控制杂志,2017,21(7):684-687,692.
[16] 陶然,武鸣,覃玉江,等. 江苏省成年人代谢综合征流行特征及其不同诊断标准的对比研究[J]. 吉林大学学报(医学版),2015,41(1):181-189.
[17] 秘迎君. 中国九省成人超重、肥胖的患病率及其与全死因死亡风险的关联研究[D]. 石家庄:河北医科大学,2017.
[18] KUZUYA M, ANDO F,IGUCHI A,et al. Age-specific change of prevalence of metabolic syndrome: longitudinal observation of large Japanese cohort[J]. Atherosclerosis, 2007,191(2): 305-312.
[19] SANTOS A C,EBRAHIM S,BARROS H. Gender, socio-economic status and metabolic syndrome in middle-aged and old adults[J]. BMC Public Health,2008,8:62.
[20] PARK H S,OH S W,CHO S I, et al. The metabolic syndrome and associated lifestyle factors among South Korean adults[J]. Int J Epidemiol,2004,33(2): 328-336.
[21] 张海滨,刘学双,康凯燕,等. 代谢综合征的影响因素分析[J]. 中国卫生统计,2013,30(1):93-94.
[2] LU J L, WANG L M, LI M, et al. Metabolic syndrome among adults in China: the 2010 China Noncommunicable Disease Surveillance[J]. J Clin Endocrinol Metab, 2017,102(2): 507-515.
[3] PRASAD D S, KABIR Z, DASH A K, et al. Prevalence and risk factors for metabolic syndrome in Asian Indians: a community study from urban Eastern India[J]. J Cardiovasc Dis Res, 2012, 3(3): 204-211.
[4] AGUILAR M, BHUKET T, TORRES S, et al. Prevalence of the metabolic syndrome in the United States, 2003-2012[J]. JAMA, 2015, 313(19): 1973-1974.
[5] HUH J H, KANG D R, JANG J Y, et al. Metabolic syndrome epidemic among Korean adults: Korean survey of Cardiometabolic Syndrome (2018) [J]. Atherosclerosis, 2018,277: 47-52.
[6] VERNAY M, SALANAVE B, DE P C, et al. Metabolic syndrome and socioeconomic status in France: the French Nutrition and Health Survey (ENNS, 2006-2007) [J]. Int J Public Health, 2013, 58(6): 855-864.
[7] ALBERTI K G M M, ECKEL R H, GRUNDY S M,et al. Harmonizing the metabolic syndrome a joint Interim Statement of the International Diabetes Federation Task Force on Epidemiology and Prevention; National Heart, Lung, and Blood Institute; American Heart Association; World Heart Federation; International Atherosclerosis Society; and International Association for the Study of Obesity[J]. Circulation, 2009,120(16): 1640-1645.
[8] 中国肥胖问题工作组. 中国成人超重和肥胖症预防与控制指南(节录)[J]. 营养学报, 2004,26(1):1-4.
[9] 中国2型糖尿病防治指南(2013年版)[J]. 中国糖尿病杂志,2014,22(8):2-42.
[10] 刘力生. 中国高血压防治指南2010[J]. 中华高血压杂志,2011,19(8):701-743.
[11] 中国成人血脂异常防治指南制订联合委员会. 中国成人血脂异常防治指南[J]. 中华心血管病杂志,2007,35(5):390-419.
[12] 丁贤彬,毛德强,沈卓之,等. 重庆市城市居民代谢综合征患病率及影响因素分析[J]. 华南预防医学,2017,43 (4):301-305.
[13] 宋雅珊,王明军,叶旭东,等. 广西地区成年人代谢综合征患病率横断面调查[J]. 临床肾脏病杂志,2017,17 (5):271-275.
[14] 洪汝丹,陆林,杨永芳,等. 云南省6县(区)常住居民代谢综合征患病率及其影响因素分析[J]. 中国慢性病预防与控制,2013,21 (5):530-535.
[15] 董莹,王馨,张林峰,等. 新疆地区≥35岁人群代谢综合征患病率情况调查[J]. 中华疾病控制杂志,2017,21(7):684-687,692.
[16] 陶然,武鸣,覃玉江,等. 江苏省成年人代谢综合征流行特征及其不同诊断标准的对比研究[J]. 吉林大学学报(医学版),2015,41(1):181-189.
[17] 秘迎君. 中国九省成人超重、肥胖的患病率及其与全死因死亡风险的关联研究[D]. 石家庄:河北医科大学,2017.
[18] KUZUYA M, ANDO F,IGUCHI A,et al. Age-specific change of prevalence of metabolic syndrome: longitudinal observation of large Japanese cohort[J]. Atherosclerosis, 2007,191(2): 305-312.
[19] SANTOS A C,EBRAHIM S,BARROS H. Gender, socio-economic status and metabolic syndrome in middle-aged and old adults[J]. BMC Public Health,2008,8:62.
[20] PARK H S,OH S W,CHO S I, et al. The metabolic syndrome and associated lifestyle factors among South Korean adults[J]. Int J Epidemiol,2004,33(2): 328-336.
[21] 张海滨,刘学双,康凯燕,等. 代谢综合征的影响因素分析[J]. 中国卫生统计,2013,30(1):93-94.