槐米中芦丁提取工艺及其应用研究
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摘要
通过用碱溶酸提法对槐米提取工艺的改进提高芦丁提取效率,主要从pH、温度方面探索如何提高提取效率。利用控制变量法找出最合适的提取pH值和温度值,发现在pH为3.0和10.0,温度在80.0℃时提取效率最高。
In order to improve the extraction efficiency of rutin from Sophora japonica L. by improving the extraction process of Sophora japonica L. with alkali-acid solution, the paper explored how to improve the extraction efficiency from the aspects of pH and temperature. The control variable method was used to find out the most suitable extraction pH value and temperature value, and it was found that the extraction efficiency was the highest when the pH value was 3.0 and 10.0,and the temperature was 80.0 ℃.
In order to improve the extraction efficiency of rutin from Sophora japonica L. by improving the extraction process of Sophora japonica L. with alkali-acid solution, the paper explored how to improve the extraction efficiency from the aspects of pH and temperature. The control variable method was used to find out the most suitable extraction pH value and temperature value, and it was found that the extraction efficiency was the highest when the pH value was 3.0 and 10.0,and the temperature was 80.0 ℃.
引文
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[8]Ye M,Li Y,Yan Y,et al.Determination of flavonoids in Semen Cuscutae by RP-HPLC[J].Journal of Pharmaceutical and Biomedical Analysis,2002,28(3):621-628.
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[2]李锋,唐辉,韦宵,等.广西全州县金槐生产存在的问题及发展对策[J].广西科学院学报,2009,25(2):130-134.
[3]温著红,李宗孝,高拴平.芦丁生产新工艺[J].中医药学报,2004,32(4):2022,63.
[4]EI Dnditys E,Khalifa TL,Annarha,et al.Chemical and biological study of Sophora japonica L.growing in Egypt[J].Al Azhar JPharmSci,1999,24:230.
[5]许植方,韩公羽.国产槐花米成分研究(Ⅱ)[J].药学学报,1957,5(3):205.
[6]李茂星,谢景文,葛欣.芦丁的药效学研究进展[J].华西药学杂志,2000,15(6):450-451.
[7]王艳芳,王新华,朱宇同.槲皮素药理作用研究进展[J].天然产物研究与开发,2003,15(2):171-173.
[8]Ye M,Li Y,Yan Y,et al.Determination of flavonoids in Semen Cuscutae by RP-HPLC[J].Journal of Pharmaceutical and Biomedical Analysis,2002,28(3):621-628.
[9]姜廷福,师彦平.天然产物黄酮类化合物的高效液相色谱分析[J].分析测试技术与仪器,2002,8(4):199-207.