动物应激模型的构建与应用
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摘要
应激是动物受到病原性和非病原性抗原的刺激时产生精神萎靡、食欲下降,嗜睡、生长缓慢等现象。因此,构建可靠的动物应激模型,对于揭示动物应激机制及研制抗应激添加剂具有重要意义。主要综述了应激模型的构建方法及其在动物生产中的应用,以期为动物生产中应激防治提供依据。
Stress is a phenomenon, of which an animal is stimulated by pathogenic and non-pathogenic antigens, resulting in suffer from depression, loss of appetite, lethargy, and slow growth. Therefore, it is of great significance to establish reliable animal stress model to reveal the mechanism of animal stress and to develop an anti stress additive. This paper mainly reviews the establishment of stress models and its application in animal production, so as to provide basis for the prevention and treatment of stress in animal production.
Stress is a phenomenon, of which an animal is stimulated by pathogenic and non-pathogenic antigens, resulting in suffer from depression, loss of appetite, lethargy, and slow growth. Therefore, it is of great significance to establish reliable animal stress model to reveal the mechanism of animal stress and to develop an anti stress additive. This paper mainly reviews the establishment of stress models and its application in animal production, so as to provide basis for the prevention and treatment of stress in animal production.
引文
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[2]刘玉兰,李德发,龚利敏,等.免疫应激对断奶仔猪免疫和神经内分泌激素的影响[J].中国畜牧杂志,2004,40(4):4-6.
[3]Plessers E,Wyns H,Watteyn A,et al.Characterization of an intravenous lipopolysaccharide inflammation model in calves with respect to the acute-phase response[J].Veterinary Immunology&Immunopathology,2015,163(1/2):46-56.
[4]Baert K,Duchateau L,De B S,et al.Antipyretic effect of oral sodium salicylate after an intravenous E.coli LPS injection in broiler chickens[J].British Poultry Science,2005,46(2):137.
[5]张锦玥,林诗宇,赵瑾,等.竹叶黄酮对免疫抑制肉鸡生产性能和免疫功能的影响[J].四川农业大学学报,2015,33(3):314-318.
[6]Wright K J,Balaji R,Hill C M,et al.Integrated adrenal,somatotropic,and immune responses of growing pigs to treatment with lipopolysaccharide[J].Journal of Animal Science,2000,78(7):1892.
[7]Li K,Zhang P,Shi B,et al.Dietary Artemisia ordosica extract alleviating immune stress in broilers exposed to lipopolysaccharide[J].2017,16(2):1-7.
[8]张玲.壳寡糖对脂多糖和环磷酰胺应激仔猪生产性能和免疫功能的影响[D].雅安:四川农业大学,2013.
[9]贾安峰,冯京海,张敏红,等.递增注射脂多糖诱导慢性免疫应激对仔猪生长性能的影响[J].动物营养学报,2015,27(6):1868-1874.
[10]潘迪子,李国军,胡贵丽,等.活性酵母对脂多糖应激黄羽肉鸡肠道健康的影响[J].动物营养学报,2017,29(7):2520-2534.
[11]Fan Y,Ma L,Zhang W,et al.Microemulsion can improve the immuneenhancing activity of propolis flavonoid on immunosuppression and immune response[J].International Journal of Biological Macromolecules,2014,63:126-132.
[12]张锦玥,林诗宇,赵瑾,等.竹叶黄酮对免疫抑制肉鸡生产性能和免疫功能的影响[J].四川农业大学学报,2015,33(3):314-318.
[13]鲍伟光,郝月,崔艳军,等.敌草快和硫辛酸对育肥猪肠道结构及消化功能的影响[J].动物营养学报,2016,28(10):3264-3274.
[14]谢梦蕊,李秋明,邱思奇,等.地鳖肽对氧化应激肉仔鸡生长性能、肉品质、脏器指数和抗氧化能力的影响[J].动物营养学报,2018(5):1726-1735
[15]Cao S,Wu H,Wang C,et al.Diquat-induced Oxidative Stress Increases Intestinal Permeability,Impairs Mitochondrial Function and Triggers Mitophagy in Piglets[J].Journal of Animal Science,2018.
[16]钟光,王进圣,王炎辉,等.微生态制剂对应激雄性肉仔鸡生长性能和肠道健康的影响[J].动物营养学报,2017,29(11):4123-4130.
[17]Mao X,LüM,Yu B,et al.The effect of dietary tryptophan levels on oxidative stress of liver induced diquat in weaned piglets[J].Journal of Animal Science and Biotechnology,2015,5(1):1-7.
[18]刘松.苜蓿多糖的提取及其对蛋鸡抗氧化能力的影响[D].北京:中国农业科学院,2016.
[19]Dai C,Zheng C Q,Meng F J,et al.VSL#3 probiotics exerts the antiinflammatory activity via PI3k/Akt and NF-κB pathway in rat model of DSS-induced colitis[J].Molecular&Cellular Biochemistry,2013,374(1/2):1-11.
[20]Zhang W H,Gao F,Zhu Q F,et al.Dietary sodium butyrate alleviates the oxidative stress induced by corticosterone exposure and improves meat quality in broiler chickens[J].Poult Sci.,2011,90(11):2592-2599.
[21]李欢,黄牛,何流琴,等.谷氨酰胺对脂多糖诱导的断奶仔猪氧化应激的影响[J].动物营养学报,2017,29(4):1350-1358.
[22]郝二英,陈辉,赵宇,等.冷热应激对蛋鸡生产性能、蛋品质的影响[J].中国家禽,2015,37(13):39-42.
[23]Zhao F Q,Zhang Z W,Wang C,et al.The role of heat shock proteins in inflammatory injury induced by cold stress in chicken hearts[J].Cell Stress&Chaperones,2013,18(6):773-783.
[24]Zhao F Q,Zhang Z W,Qu J P,et al.Cold stress induces antioxidants and Hsps in chicken immune organs[J].Cell Stress&Chaperones,2014,19(5):635-48.
[25]Lord-Fontaine S,Averill-Bates D A.Heat shock inactivates cellular antioxidant defenses against hydrogen peroxide:protection by glucose[J].Free Radical Biology&Medicine,2002,32(8):752-765.
[26]Lin H,Decuypere E,Buyse J.Acute heat stress induces oxidative stress in broiler chickens.[J].Comparative Biochemistry&Physiology Part A,2006,144(1):11-17.
[27]李丽.鸡持续冷应激启动Nrf2抗氧化信号转导路径的研究[D].合肥:安徽农业大学,2013.
[28]王继强,龙强,李爱琴,等.鸡的热应激及抗热应激添加剂的应用研究[J].饲料工业,2008,29(15):20-22.
[29]冯跃进,顾宪红.热应激对猪肉品质的影响及其机制的研究进展[J].中国畜牧兽医,2013,40(2):96-99.
[30]杨游,袁志琳,董国忠,等.饲粮中添加脂肪酸钙和烟酸铬对热应激奶牛产奶性能、生理指标及血清生化指标的影响[J].动物营养学报,2012,24(1):145-151.
[31]Costa M J R P D,Silva R G D,Souza R C D.Effect of air temperature and humidity on ingestive behaviour of sheep[J].International Journal of Biometeorology,1992,36(4):218-222.
[32]田军权,何流琴,黄牛,等.谷氨酰胺对脂多糖应激仔猪生长性能及血清生化指标的影响[J].动物营养学报,2017,29(5):1670-1677.
[33]Zhang P F,Shi B L,Su J L,et al.Relieving effect of Artemisia argyi,aqueous extract on immune stress in broilers[J].Journal of Animal Physiology&Animal Nutrition,2016,101(2).
[34]王娟娟.硒和维生素E缓解肉鸡免疫应激的效果[D].杨凌:西北农林科技大学,2013.
[35]Gross J J,Grossenr?sti L,Héritier R,et al.Inflammatory and metabolic responses to an intramammary lipopolysaccharide challenge in early lactating cows supplemented with conjugated linoleic acid[J].Journal of Animal Physiology&Animal Nutrition,2017,102(2).
[36]Wang J,Guo C,Wei Z,et al.Morin suppresses inflammatory cytokine expression by downregulation of nuclear factor-κB and mitogen-activated protein kinase(MAPK)signaling pathways in lipopolysaccharide-stimulated primary bovine mammary epithelial cells[J].Journal of Dairy Science,2016,99(4):3016-3022.
[37]王平.益生素对免疫应激肉仔鸡生长性能及血液指标的影响[D].晋中:山西农业大学,2013.
[38]韩杰,张飞,边连全.刺五加多糖对免疫应激断奶仔猪免疫器官指数、粪便微生物菌群数量和胃肠道pH的影响[J].动物营养学报,2014,26(8):2314-2319.
[39]赵娇.葡萄籽原花青素缓解氧化应激仔猪肝脏损伤及可能机制研究[D].雅安:四川农业大学,2013.
[40]Yin J,Liu M,Ren W,et al.Effects of Dietary Supplementation with Glutamate and Aspartate on Diquat-Induced Oxidative Stress in Piglets[J].Plos One,2015,10(4):e0122893.
[41]徐静.猪氧化应激模型构建以及茶多酚的抗应激效应的研究[D]..雅安:四川农业大学,2009.
[42]石慧芹,周建川,马秋刚,等.酵母硒和维生素E对氧化应激状态蛋鸡抗氧化能力的影响[J].中国畜牧杂志,2013,49(21):37-40.
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