0.1% Roflamycoin悬浮剂的研制及其对黄瓜白粉病的防效
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摘要
[目的]研制玫瑰黄链霉菌Men-myco-93-63抗菌活性代谢产物roflamycoin抗生素悬浮剂。[方法]分别采用流点法及尝试法对润湿剂、分散剂和增稠剂等助剂进行筛选及优化,最终采用湿法研磨超微粉碎法研制了0.1% roflamycoin抗生素悬浮剂,对其性能指标进行测定,并将其用于田间黄瓜白粉病的防治。[结果]以质量分数为0.1% rofalmycoin抗生素为有效成分、1%DS 97为润湿剂、1%亨斯迈2208及2% LT-767C为分散剂、1%硅酸铝镁及0.1%黄原胶为增稠剂和5%的乙二醇为防冻剂研制的0.1% rofalmycoin悬浮剂性能良好、悬浮率高、热贮稳定性好。田间该悬浮剂的250、500、1000倍防治效果均达到80%以上,其中1000倍防效达到88.09%。[结论]0.1% Roflamycoin悬浮剂对黄瓜白粉病有较好的防治效果。
[Aims] The rofla mycoin 0.1% SC, the metabolite of streptomyces rose of lavus Me-myco-93-63, was prepared and its efficacy on the cucumber powdery mildew was studied. [Methods] A series of wetting agent,dispersing agent, thickening agent and other agent were screened and optimized by flow point method and selection method. [Results] The wet milling method was ultimately chosen as the optimal method to prepare the roflamycoin0.1% SC which contains the following formula: roflamycoin 0.1% as active ingredient, DS 97 1% as wetting agent,Huntsman 2208 1% as dispersing agent, xanthan gum 0.1% and veegum 1% as thickening agent, ethanediol 5% as antifreezing agent and SAG-630 0.2% as defaming agent. In the field test, the control effects of 250, 500 and 1000 times of roflamycoin SC were all more than 80%, of which the 1000 times was 88.09%. [Conclusions] The roflamycoin 0.1% SC showed good effect on cucumber powdery mildew.
[Aims] The rofla mycoin 0.1% SC, the metabolite of streptomyces rose of lavus Me-myco-93-63, was prepared and its efficacy on the cucumber powdery mildew was studied. [Methods] A series of wetting agent,dispersing agent, thickening agent and other agent were screened and optimized by flow point method and selection method. [Results] The wet milling method was ultimately chosen as the optimal method to prepare the roflamycoin0.1% SC which contains the following formula: roflamycoin 0.1% as active ingredient, DS 97 1% as wetting agent,Huntsman 2208 1% as dispersing agent, xanthan gum 0.1% and veegum 1% as thickening agent, ethanediol 5% as antifreezing agent and SAG-630 0.2% as defaming agent. In the field test, the control effects of 250, 500 and 1000 times of roflamycoin SC were all more than 80%, of which the 1000 times was 88.09%. [Conclusions] The roflamycoin 0.1% SC showed good effect on cucumber powdery mildew.
引文
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[3]RYCHNOVSKY S D,K HIRE U R,YANG Guang.Total Synthesis of the Polyene Macrolide Roflamycoin[J].Journal of The American Chemical Society,1997,119(8):2058-2059.
[4]韩兴.玫瑰黄链霉菌Men-myco-93-63抗菌物质的研究及其发酵培养基的优化(硕士论文)[D].保定:河北农业大学,2016.
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[7]刘景坤,刘润峰,宋建华,等.50%噻虫嗪悬浮种衣剂的研制及其对棉花蚜虫的防治效果[J].农药学学报,2015,17(1):60-67.
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[11]冯建国,项盛,郁倩瑶,等.农药悬浮剂物理稳定性的研究进展[J].日用化学工业,2015(12):710-714.
[12]王丹丹.D-松醇对黄瓜白粉病的作用方式、作用机理及其和其它药剂的复配研究(硕士论文)[D].上海:上海交通大学,2013.
[2]SCHLEGEL R,THRUM H,ZIELINSKI J,et al.The Structure of Roflamycoin,a New Polyene Macrolide Antifungal Antibiotic[J].The Journal of Antibiotics,1981,34(1):122-123.
[3]RYCHNOVSKY S D,K HIRE U R,YANG Guang.Total Synthesis of the Polyene Macrolide Roflamycoin[J].Journal of The American Chemical Society,1997,119(8):2058-2059.
[4]韩兴.玫瑰黄链霉菌Men-myco-93-63抗菌物质的研究及其发酵培养基的优化(硕士论文)[D].保定:河北农业大学,2016.
[5]潘立刚,陶岭梅,张兴.农药悬浮剂研究进展[J].植物保护,2005,31(2):17-20.
[6]仲苏林.农药悬浮剂的开发现状和展望[J].世界农药,2010,32(3):47-51.
[7]刘景坤,刘润峰,宋建华,等.50%噻虫嗪悬浮种衣剂的研制及其对棉花蚜虫的防治效果[J].农药学学报,2015,17(1):60-67.
[8]刘广文.现代农药剂型加工技术[M].北京:化学工业出版社,2013.
[9]楼少巍.GB/T 14825-2006.农药悬浮率测定方法[S].北京:中国标准出版社,2007.
[10]徐范.GB/T 1601-93.农药p H值的测定方法[S].北京:中国标准出版社,1994.
[11]冯建国,项盛,郁倩瑶,等.农药悬浮剂物理稳定性的研究进展[J].日用化学工业,2015(12):710-714.
[12]王丹丹.D-松醇对黄瓜白粉病的作用方式、作用机理及其和其它药剂的复配研究(硕士论文)[D].上海:上海交通大学,2013.