噻虫嗪及其代谢物在大葱中的消解动态及最终残留
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摘要
[目的]研究噻虫嗪及其代谢物在大葱中的消解动态及最终残留量,评价其在大葱上的使用安全性,为噻虫嗪在大葱中的最大残留限量标准的制定提供科学依据。[方法]通过2016—2017年在吉林、山东2年2地的田间小区试验和高效液相色谱串联质谱分析技术研究2%噻虫嗪颗粒剂在大葱中的消解动态及其最终残留量。[结果]吉林、山东省2年2地的残留数据结果表明:噻虫嗪在大葱植株和土壤中的半衰期分别为0.2~1.8、4.4~14.9 d。收获期大葱植株和土壤中噻虫嗪及其代谢物的残留量分别为0.015~0.117、0.019~0.233 mg/kg。[结论]综合多方面因素,建议我国2%噻虫嗪颗粒剂在大葱上施用,最高制剂用药量40 500 g/hm2(810 g a.i./hm2)最多施药1次。推荐我国对噻虫嗪在大葱中的最大允许残留水平(MRL)值为0.50 mg/kg。
[Aims] The degradation and final residues of thiamethoxam and its metabolites in welsh onion were investigated to evaluate its application safety. [Methods] Field experiments at Jilin and Shandong were conducted in2016-2017, and liquid chromatography tandem mass spectrometry were carried out to study residual decline and final residues of thiamethoxam in welsh onion and soil. [Results] The average degradation half-lives of thiamethoxam at high dosage(spraying for one time) were 0.2-1.8 d in welsh onion and 4.4-14.9 d in soil. The results of the final residue experiments showed that the final residues of thiamethoxam and its metabolites in welsh onion and soil were 0.015-0.117 and 0.019-0.233 mg/kg, respectively. [Conclusions] Comprehensive multifaceted factors, the thiamethoxam 2% GR could be applied on welsh onion once with the maximum dosage of 40 500 g/ha(810 g a.i./ha), 0.50 mg/kg was recommended as maximum residue level(MRL) for thiamethoxam in welsh onion.
[Aims] The degradation and final residues of thiamethoxam and its metabolites in welsh onion were investigated to evaluate its application safety. [Methods] Field experiments at Jilin and Shandong were conducted in2016-2017, and liquid chromatography tandem mass spectrometry were carried out to study residual decline and final residues of thiamethoxam in welsh onion and soil. [Results] The average degradation half-lives of thiamethoxam at high dosage(spraying for one time) were 0.2-1.8 d in welsh onion and 4.4-14.9 d in soil. The results of the final residue experiments showed that the final residues of thiamethoxam and its metabolites in welsh onion and soil were 0.015-0.117 and 0.019-0.233 mg/kg, respectively. [Conclusions] Comprehensive multifaceted factors, the thiamethoxam 2% GR could be applied on welsh onion once with the maximum dosage of 40 500 g/ha(810 g a.i./ha), 0.50 mg/kg was recommended as maximum residue level(MRL) for thiamethoxam in welsh onion.
引文
[1]崔淑华.大葱中农药多残留检测技术及推荐使用品种的残留动态研究(博士论文)[D].泰安:山东农业大学,2012.
[2]张庆臣,薛明,王钲,等.新烟碱类等杀虫剂对葱蝇的毒力及其对生长发育和繁殖的影响[J].植物保护学报,2011,38(2):159-165.
[3]张鹏,赵云贺,韩京坤,等.不同施药方式下噻虫嗪和噻虫胺对韭菜迟眼蕈蚊的防治效果[J].植物保护学报,2015,42(4):645-650.
[4]MORAIS E H D C,NEVES A A,MORAIS P H D.Determination of Thiamethoxam,Triadimenol and Deltamethrin in Pineapple Using SLE-LTP Extraction and Gas Chromatography[J].Food Control,2014,42(2):9-17.
[5]刘博静,范小振,王茜,等.22%噻虫嗪·高效氯氟氰菊酯悬乳剂气相色谱分析[J].农药,2017,56(2):116-118.
[6]陈国峰,刘峰,张晓波,等.气质联用法检测麦田中的噻虫嗪和高效氯氟氰菊酯残留[J].现代农药,2015,14(5):39-41.
[7]ABDALRAHMAN S H.Residue and Dissipation Kinetics of Thiamethoxam in a Vegetable-field Ecosystem Using Qu ECh ERS Methodology Combined with HPLC-DAD[J].Food Chemistry,2014,159(6):1-4.
[8]ABDELGHANY M F,HUSSEIN L A,EL N A,et al.Simultaneous Determination of Eight Neonicotinoid Insecticide Residues and Two Primary Metabolites in Cucumbers and Soil by Liquid Chromatography-tandem Mass Spectrometry Coupled with Qu ECh ERS[J].J Chromatogr B Analyt Technol Biomed Life Sci,2016,1031:15-28.
[9]丁葵英,许文娟,郭礼强,等.液相色谱-串联质谱法测定葱属蔬菜中的噻虫嗪、多菌灵等5种农药的残留量[J].食品与生物技术学报,2016,35(4):424-428.
[10]王东,侯传金,赵尔成,等.盐析辅助均相液液萃取/分散固相萃取-超高效液相色谱串联质谱法测定蜂蜜中新烟碱类农药残留[J].分析测试学报,2015,34(6):681-685.
[11]罗梅梅,铁柏清,贺敏,等.超高效液相色谱-串联质谱法检测韭菜中噻虫嗪及其代谢物噻虫胺[J].农药,2014,53(7):494-496,508.
[12]刘炎,欧阳迪庆,叶玉凤,等.Qu ECh ERS结合超高效液相色谱-串联质谱法同时测定番茄中噻虫嗪、噻虫胺、螺虫乙酯及其代谢物残留[J].分析测试学报,2017,36(12):1431-1438.
[13]FAN Yin-jun,SHI Xue-yan.Characterization of the Metabolic Transformation of Thiamethoxam to Clothianidin in Helicoverpa Armigera Larvae by SPE Combined UPLC-MS/MS and Its Relationship with the Toxicity of Thiamethoxam to Helicoverpa armigera Larvae[J].Journal of Chromatography B Analytical Technologies in the Biomedical&Life Sciences,2017,1061-1062:349.
[14]李慧思,黄超群,蒋沁婷,等.在线净化-液相色谱-串联质谱法测定茶叶中5种烟碱类农药残留[J].色谱,2016,34(3):263-269.
[15]RAHMAN M M,FARHA W,ABD EL-ATY A M,et al.Dynamic Behaviour and Residual Pattern of Thiamethoxam and Its Metabolite Clothianidin in Swiss Chard Using Liquid Chromatography-tandem Mass Spectrometry[J].Food Chemistry,2015,174:248-255.
[16]冯义志,潘金菊,齐晓雪,等.噻虫嗪及其代谢物噻虫胺在韭菜和土壤中的残留消解动态及残留量[J].现代农药,2016,15(5):45-48.
[17]王运儒,秦玉燕,杨秀娟,等.40%氯虫·噻虫嗪水分散粒剂在辣椒及土壤中的残留消解动态[J].江苏农业学报,2018(1):207-212.
[18]陈国峰,李雪茹,刘峰,等.高效氯氟氰菊酯、噻虫嗪及其代谢物噻虫胺在小麦中的残留及消解动态分析[J].麦类作物学报,2018,38(1):119-125.
[19]农业部.GB 2673—2016食品安全国家标准:食品中农药最大残留限量[S].北京:中国标准出版社,2016.
[20]NY/T 788—2004.农药残留试验准则[S].北京:中国农业出版社,2004.
[21]农业部药检所.农药登记田间试验标准操作规程[M].北京:中国标准出版社,2007:3-38.
[2]张庆臣,薛明,王钲,等.新烟碱类等杀虫剂对葱蝇的毒力及其对生长发育和繁殖的影响[J].植物保护学报,2011,38(2):159-165.
[3]张鹏,赵云贺,韩京坤,等.不同施药方式下噻虫嗪和噻虫胺对韭菜迟眼蕈蚊的防治效果[J].植物保护学报,2015,42(4):645-650.
[4]MORAIS E H D C,NEVES A A,MORAIS P H D.Determination of Thiamethoxam,Triadimenol and Deltamethrin in Pineapple Using SLE-LTP Extraction and Gas Chromatography[J].Food Control,2014,42(2):9-17.
[5]刘博静,范小振,王茜,等.22%噻虫嗪·高效氯氟氰菊酯悬乳剂气相色谱分析[J].农药,2017,56(2):116-118.
[6]陈国峰,刘峰,张晓波,等.气质联用法检测麦田中的噻虫嗪和高效氯氟氰菊酯残留[J].现代农药,2015,14(5):39-41.
[7]ABDALRAHMAN S H.Residue and Dissipation Kinetics of Thiamethoxam in a Vegetable-field Ecosystem Using Qu ECh ERS Methodology Combined with HPLC-DAD[J].Food Chemistry,2014,159(6):1-4.
[8]ABDELGHANY M F,HUSSEIN L A,EL N A,et al.Simultaneous Determination of Eight Neonicotinoid Insecticide Residues and Two Primary Metabolites in Cucumbers and Soil by Liquid Chromatography-tandem Mass Spectrometry Coupled with Qu ECh ERS[J].J Chromatogr B Analyt Technol Biomed Life Sci,2016,1031:15-28.
[9]丁葵英,许文娟,郭礼强,等.液相色谱-串联质谱法测定葱属蔬菜中的噻虫嗪、多菌灵等5种农药的残留量[J].食品与生物技术学报,2016,35(4):424-428.
[10]王东,侯传金,赵尔成,等.盐析辅助均相液液萃取/分散固相萃取-超高效液相色谱串联质谱法测定蜂蜜中新烟碱类农药残留[J].分析测试学报,2015,34(6):681-685.
[11]罗梅梅,铁柏清,贺敏,等.超高效液相色谱-串联质谱法检测韭菜中噻虫嗪及其代谢物噻虫胺[J].农药,2014,53(7):494-496,508.
[12]刘炎,欧阳迪庆,叶玉凤,等.Qu ECh ERS结合超高效液相色谱-串联质谱法同时测定番茄中噻虫嗪、噻虫胺、螺虫乙酯及其代谢物残留[J].分析测试学报,2017,36(12):1431-1438.
[13]FAN Yin-jun,SHI Xue-yan.Characterization of the Metabolic Transformation of Thiamethoxam to Clothianidin in Helicoverpa Armigera Larvae by SPE Combined UPLC-MS/MS and Its Relationship with the Toxicity of Thiamethoxam to Helicoverpa armigera Larvae[J].Journal of Chromatography B Analytical Technologies in the Biomedical&Life Sciences,2017,1061-1062:349.
[14]李慧思,黄超群,蒋沁婷,等.在线净化-液相色谱-串联质谱法测定茶叶中5种烟碱类农药残留[J].色谱,2016,34(3):263-269.
[15]RAHMAN M M,FARHA W,ABD EL-ATY A M,et al.Dynamic Behaviour and Residual Pattern of Thiamethoxam and Its Metabolite Clothianidin in Swiss Chard Using Liquid Chromatography-tandem Mass Spectrometry[J].Food Chemistry,2015,174:248-255.
[16]冯义志,潘金菊,齐晓雪,等.噻虫嗪及其代谢物噻虫胺在韭菜和土壤中的残留消解动态及残留量[J].现代农药,2016,15(5):45-48.
[17]王运儒,秦玉燕,杨秀娟,等.40%氯虫·噻虫嗪水分散粒剂在辣椒及土壤中的残留消解动态[J].江苏农业学报,2018(1):207-212.
[18]陈国峰,李雪茹,刘峰,等.高效氯氟氰菊酯、噻虫嗪及其代谢物噻虫胺在小麦中的残留及消解动态分析[J].麦类作物学报,2018,38(1):119-125.
[19]农业部.GB 2673—2016食品安全国家标准:食品中农药最大残留限量[S].北京:中国标准出版社,2016.
[20]NY/T 788—2004.农药残留试验准则[S].北京:中国农业出版社,2004.
[21]农业部药检所.农药登记田间试验标准操作规程[M].北京:中国标准出版社,2007:3-38.