甲状腺结节的现状与发展展望
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摘要
在现代医学技术逐渐发展和进步的过程中,超声检查仪器的分辨率也越来越高,并在临床中得到了广泛的应用,进而也在一定程度上提高了甲状腺结节的临床检出率。现阶段临床中在对甲状腺结节的性质进行术前判断时,常用的方法主要为单光子发射计算机断层扫描、高频超声检查、细针穿刺抽吸活检细胞学检查等。而现阶段临床中常用的治疗方法则包括西医治疗、中医治疗等。本文主要分析现阶段用于术前判断甲状腺结节良恶性的常用方法和治疗方法,并对发展进行了展望。
In the process of the development and progress of modern medical technology, the resolution of ultrasonographic instruments is getting higher and higher, and it has been widely used in clinic, which also improves the clinical detection rate of thyroid nodules to a certain extent. At present, in the preoperative judgement of the nature of thyroid nodules, the commonly used methods are single photon emission computed tomography(SPECT), high frequency ultrasound(HFUS), fine needle aspiration biopsy(FNAB) and so on. At present, the commonly used clinical treatment methods include western medicine treatment, traditional Chinese medicine treatment and so on. This article mainly analyses the common methods and treatment methods used to preoperatively judge the benign and malignant thyroid nodules, and prospects the development.
In the process of the development and progress of modern medical technology, the resolution of ultrasonographic instruments is getting higher and higher, and it has been widely used in clinic, which also improves the clinical detection rate of thyroid nodules to a certain extent. At present, in the preoperative judgement of the nature of thyroid nodules, the commonly used methods are single photon emission computed tomography(SPECT), high frequency ultrasound(HFUS), fine needle aspiration biopsy(FNAB) and so on. At present, the commonly used clinical treatment methods include western medicine treatment, traditional Chinese medicine treatment and so on. This article mainly analyses the common methods and treatment methods used to preoperatively judge the benign and malignant thyroid nodules, and prospects the development.
引文
[1]Pilli Tania,Cantara Silvia,Marzocchi Carlotta,et al.Diagnostic Value of Circulating microRNA-95 and-190 in the Differential Diagnosis of Thyroid Nodules:A Validation Study in 1000 Consecutive Patients[J].Thyroid:official journal of the American Thyroid Association,2017,27(8):35.
[2]Chew Carolyn R,Lam Tracey,Chan Steven TF,et al.Systematic differences between ultrasound and pathological evaluation of thyroid nodules:a method comparison study[J].ANZ journal of surgery,2018,88(5):464-467.
[3]薛峰,单华,孙丹,等.256层CT双期增强扫描在甲状腺腺瘤和甲状腺癌鉴别诊断中的价值[J].影像研究与医学应用,2018,2(23):4-5.
[4]张丽丽.彩色多普勒超声检查对甲状腺结节良恶性的诊断意义[J].影像研究与医学应用,2018,2(23):107-108.
[5]刘平.高频超声在甲状腺良恶性结节诊断中的价值[J].影像研究与医学应用,2018,2(23):162-163.
[6]王利利,王春梅,刘琳琳.超声诊断甲状腺结节ACR分级与病理结果对比分析[J].影像研究与医学应用,2018,2(23):166-167.
[7]周海霞,刘艳萍.多模态超声技术在甲状腺微小癌诊断中的应用[J].中国老年学杂志,2018,38(22):5443-5444.
[8]王文普,张丹,张凯,等.分析甲状腺实性结节诊断中超声引导下细针吸取活检的应用价值[J].中国医疗器械信息,2018,24(22):3-4.
[9]Beril Guler,Tugce Kiran,Dilek Sema Arici,et al.Should Core Needle Biopsy be Used in the Evaluation of Thyroid Nodules?[J].Endocrine Pathology,2016,27(4):352-358.
[10]Idil Gunes Tatar,Aydin Kurt,Kerim Bora Yilmaz,et al.The role of elastosonography,gray-scale and colour flow Doppler sonography in prediction of malignancy in thyroid nodules[J].Radiology and Oncology,2014,48(4):348-353.
[11]Arva NC,Deitch SG.Reclassification of cytologically atypical thyroid nodules based on radiologic features in pediatric patients[J].Journal of Pediatric Endocrinology&Metabolism,2015,28(8):753-760.
[12]曾婷婷.超声弹性成像和常规超声在诊断甲状腺良恶性结节中的优劣差异[J].数理医药学杂志,2018,31(11):1620-1621.
[13]吴贵标.多层螺旋CT在甲状腺良恶性结节诊断及鉴别诊断中的应用价值[J].影像研究与医学应用,2018,2(22):191-192.
[14]陈小红.多普勒超声技术对甲状腺结节诊断价值的究[J].中国医药指南,2018,16(30):161-162.
[15]吴艳辉,胡大海,韩锡铁.彩色多普勒超声诊断甲状腺结节的临床价值评估[J].现代医药卫生,2018,34(20):3198-3200.
[16]干露.超声鉴别诊断甲状腺弥漫性病变合并良恶性结节的声图像分析[J].安徽卫生职业技术学院学报,2018,17(5):26-27,29.
[17]张衡,舒政.纹理分析在甲状腺结节影像学中的研究进展[J].中国医学计算机成像杂志,2018,24(5):434-440.
[18]Koltin D,O’Gorman CS,Murphy A,et al.Pediatric thyroid nodules:ultrasonographic characteristics and inter-observer variability in prediction of malignancy[J].Journal of Pediatric Endocrinology&Metabolism Jpem,2016,29(7):789-794.
[19]Sui X,Liu HJ,Jia HL,et al.Contrast-enhanced ultrasound and real-time elastography in the differential diagnosis of malignant and benign thyroid nodules[J].Experimental&Therapeutic Medicine,2016,12(2):783.
[20]赵碧璇,张英霞.超声引导下细针细胞学检查在甲状腺结节诊断中的应用进展[J].山东医药,2018,58(38):100-102.
[21]王春玲,叶加润.甲状腺结节患者应用超声成像定性诊断的效果及其应用价值[J].中国医学创新,2018,15(28):135-138.
[22]黄冬芳,林晓丹.常规超声成像与超声弹性成像在良恶性甲状腺结节诊断中的应用效果[J].医疗装备,2018,31(18):33-34.
[23]杨淑君,黄季萌.彩色多普勒血流显像对甲状腺疾病的诊断价值[J].中国现代医生,2018,56(27):109-111,169.
[24]Zahir ST,Vakili M,Ghaneei A,et al.Ultrasound assistance in differentiating malignant thyroid nodules from benign ones[J].Journal of Ayub Medical College Abbottabad Jamc,2016,28(4):644.
[25]Wei-Ying L,Qin-Yi G,Ya-Ming LI,et al.Values of Radionuclide Imaging,Serum TSH and Ultrasonography in the Diagnoses of Thyroid Nodules[J].Journal of Isotopes,2014,27(1):15-21.
[2]Chew Carolyn R,Lam Tracey,Chan Steven TF,et al.Systematic differences between ultrasound and pathological evaluation of thyroid nodules:a method comparison study[J].ANZ journal of surgery,2018,88(5):464-467.
[3]薛峰,单华,孙丹,等.256层CT双期增强扫描在甲状腺腺瘤和甲状腺癌鉴别诊断中的价值[J].影像研究与医学应用,2018,2(23):4-5.
[4]张丽丽.彩色多普勒超声检查对甲状腺结节良恶性的诊断意义[J].影像研究与医学应用,2018,2(23):107-108.
[5]刘平.高频超声在甲状腺良恶性结节诊断中的价值[J].影像研究与医学应用,2018,2(23):162-163.
[6]王利利,王春梅,刘琳琳.超声诊断甲状腺结节ACR分级与病理结果对比分析[J].影像研究与医学应用,2018,2(23):166-167.
[7]周海霞,刘艳萍.多模态超声技术在甲状腺微小癌诊断中的应用[J].中国老年学杂志,2018,38(22):5443-5444.
[8]王文普,张丹,张凯,等.分析甲状腺实性结节诊断中超声引导下细针吸取活检的应用价值[J].中国医疗器械信息,2018,24(22):3-4.
[9]Beril Guler,Tugce Kiran,Dilek Sema Arici,et al.Should Core Needle Biopsy be Used in the Evaluation of Thyroid Nodules?[J].Endocrine Pathology,2016,27(4):352-358.
[10]Idil Gunes Tatar,Aydin Kurt,Kerim Bora Yilmaz,et al.The role of elastosonography,gray-scale and colour flow Doppler sonography in prediction of malignancy in thyroid nodules[J].Radiology and Oncology,2014,48(4):348-353.
[11]Arva NC,Deitch SG.Reclassification of cytologically atypical thyroid nodules based on radiologic features in pediatric patients[J].Journal of Pediatric Endocrinology&Metabolism,2015,28(8):753-760.
[12]曾婷婷.超声弹性成像和常规超声在诊断甲状腺良恶性结节中的优劣差异[J].数理医药学杂志,2018,31(11):1620-1621.
[13]吴贵标.多层螺旋CT在甲状腺良恶性结节诊断及鉴别诊断中的应用价值[J].影像研究与医学应用,2018,2(22):191-192.
[14]陈小红.多普勒超声技术对甲状腺结节诊断价值的究[J].中国医药指南,2018,16(30):161-162.
[15]吴艳辉,胡大海,韩锡铁.彩色多普勒超声诊断甲状腺结节的临床价值评估[J].现代医药卫生,2018,34(20):3198-3200.
[16]干露.超声鉴别诊断甲状腺弥漫性病变合并良恶性结节的声图像分析[J].安徽卫生职业技术学院学报,2018,17(5):26-27,29.
[17]张衡,舒政.纹理分析在甲状腺结节影像学中的研究进展[J].中国医学计算机成像杂志,2018,24(5):434-440.
[18]Koltin D,O’Gorman CS,Murphy A,et al.Pediatric thyroid nodules:ultrasonographic characteristics and inter-observer variability in prediction of malignancy[J].Journal of Pediatric Endocrinology&Metabolism Jpem,2016,29(7):789-794.
[19]Sui X,Liu HJ,Jia HL,et al.Contrast-enhanced ultrasound and real-time elastography in the differential diagnosis of malignant and benign thyroid nodules[J].Experimental&Therapeutic Medicine,2016,12(2):783.
[20]赵碧璇,张英霞.超声引导下细针细胞学检查在甲状腺结节诊断中的应用进展[J].山东医药,2018,58(38):100-102.
[21]王春玲,叶加润.甲状腺结节患者应用超声成像定性诊断的效果及其应用价值[J].中国医学创新,2018,15(28):135-138.
[22]黄冬芳,林晓丹.常规超声成像与超声弹性成像在良恶性甲状腺结节诊断中的应用效果[J].医疗装备,2018,31(18):33-34.
[23]杨淑君,黄季萌.彩色多普勒血流显像对甲状腺疾病的诊断价值[J].中国现代医生,2018,56(27):109-111,169.
[24]Zahir ST,Vakili M,Ghaneei A,et al.Ultrasound assistance in differentiating malignant thyroid nodules from benign ones[J].Journal of Ayub Medical College Abbottabad Jamc,2016,28(4):644.
[25]Wei-Ying L,Qin-Yi G,Ya-Ming LI,et al.Values of Radionuclide Imaging,Serum TSH and Ultrasonography in the Diagnoses of Thyroid Nodules[J].Journal of Isotopes,2014,27(1):15-21.