激光虹膜切除术在早期原发性闭角型青光眼中的疗效观察
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摘要
目的探讨激光虹膜切除术临床治疗早期原发性闭角型青光眼的效果。方法随机选取170例早期原发性闭角型青光眼患者作为研究对象,分为观察组和对照组各85例,观察组患者在甘露醇联合毛果芸香碱药物治疗的基础上采取激光虹膜切除术治疗,对照组采取单纯的甘露醇联合毛果芸香碱药物治疗,对研究进行回顾性分析,比较两组患者治疗有效率及治疗后眼内压和视力的水平。结果观察组治疗有效率(90.6%)明显高于对照组(80.0%)且治疗后的眼内压和视力水平(18.67±2.34,0.8±0.2)明显优于对照组(23.06±1.07,0.5±0.1),差异有统计学意义(P<0.05)。结论激光虹膜切除术临床治疗早期原发性闭角型青光眼的效果显著,有效降低了患者的眼内压且提高了患者的视力水平,治疗有效率明显提高,改善了患者的生活质量,值得在临床推广应用。
Objective To discuss the effect of laser iridectomy in clinical treatment of early primary angle-closure glaucoma. Methods 170 cases of patients with early primary angle-closure glaucoma were selected as the research object and divided into two groups with 85 cases in each, the observation group were treated with laser iridectomy on the basis of mannitol combined with pilocarpine, the control group were treated with simple mannitol combined with pilocarpine, the research was retrospectively analyzed, and the treatment effective rates, intra-ocular pressures and vision levels after treatment were compared between the two groups. Results The treatment effective rate in the observation group was obviously higher than that in the control group(90.6% vs 80.0%), the intra-ocular pressure and vision level after treatment in the observation group were obviously better than those in the control group, [(18.67 ±2.34),(0.8 ±0.2) vs(23.06 ±1.07),(0.5 ±0.1)], and the differences were statistically significant P<0.05. Conclusion The effect of laser iridectomy in clinical treatment of early primary angle-closure glaucoma is obvious, which effectively decreases the patient's intra-ocular pressure and improve the patient's vision level, the treatment effective rate was obviously improved, and it improves the patient's quality of life, and it is worth clinical promotion and application.
Objective To discuss the effect of laser iridectomy in clinical treatment of early primary angle-closure glaucoma. Methods 170 cases of patients with early primary angle-closure glaucoma were selected as the research object and divided into two groups with 85 cases in each, the observation group were treated with laser iridectomy on the basis of mannitol combined with pilocarpine, the control group were treated with simple mannitol combined with pilocarpine, the research was retrospectively analyzed, and the treatment effective rates, intra-ocular pressures and vision levels after treatment were compared between the two groups. Results The treatment effective rate in the observation group was obviously higher than that in the control group(90.6% vs 80.0%), the intra-ocular pressure and vision level after treatment in the observation group were obviously better than those in the control group, [(18.67 ±2.34),(0.8 ±0.2) vs(23.06 ±1.07),(0.5 ±0.1)], and the differences were statistically significant P<0.05. Conclusion The effect of laser iridectomy in clinical treatment of early primary angle-closure glaucoma is obvious, which effectively decreases the patient's intra-ocular pressure and improve the patient's vision level, the treatment effective rate was obviously improved, and it improves the patient's quality of life, and it is worth clinical promotion and application.
引文
[1]赵恩贤,秦继跃.甘露醇联合毛果芸香碱治疗原发性急性闭角型青光眼的疗效观察[J].中国民康医学,2013(18):45-46.
[2]申爱军,高永杰,贾艳红.两种术式治疗早期慢性闭角型青光眼的远期疗效[J].国际眼科杂志,2015(5):895-897.
[3]方敏,胡忆群,陈聪玲,等.早期原发性闭角型青光眼合并白内障的手术治疗[J].国际眼科杂志,2012(5):926-927.
[4]边俊杰,戴惟葭,刘大川.应用OCT评价激光周边虹膜成形联合切除术治疗临床前期原发性闭角型青光眼的有效性[J].国际眼科杂志,2015(12):2107-2109.
[5]边俊杰,戴惟葭,刘大川.原发性急性闭角型青光眼眼前节生物测量参数的探讨[J].国际眼科杂志,2015,15(2):283-285.
[6]李松峰,常海敏.前房穿刺术联合激光周边虹膜切除术治疗急性原发性闭角型青光眼[J].眼科新进展,2013,33(6):568-570.
[7]郑策.早期原发性闭角型青光眼应用激光虹膜切除术治疗的效果研究[J].中国医学创新,2015(24):111-112.
[8]孙淑娟.综合手术治疗青光眼临床效果分析[J].中国卫生标准管理,2015,6(7):78-79.
[2]申爱军,高永杰,贾艳红.两种术式治疗早期慢性闭角型青光眼的远期疗效[J].国际眼科杂志,2015(5):895-897.
[3]方敏,胡忆群,陈聪玲,等.早期原发性闭角型青光眼合并白内障的手术治疗[J].国际眼科杂志,2012(5):926-927.
[4]边俊杰,戴惟葭,刘大川.应用OCT评价激光周边虹膜成形联合切除术治疗临床前期原发性闭角型青光眼的有效性[J].国际眼科杂志,2015(12):2107-2109.
[5]边俊杰,戴惟葭,刘大川.原发性急性闭角型青光眼眼前节生物测量参数的探讨[J].国际眼科杂志,2015,15(2):283-285.
[6]李松峰,常海敏.前房穿刺术联合激光周边虹膜切除术治疗急性原发性闭角型青光眼[J].眼科新进展,2013,33(6):568-570.
[7]郑策.早期原发性闭角型青光眼应用激光虹膜切除术治疗的效果研究[J].中国医学创新,2015(24):111-112.
[8]孙淑娟.综合手术治疗青光眼临床效果分析[J].中国卫生标准管理,2015,6(7):78-79.