不同锌制剂治疗小儿抗生素相关性腹泻的临床效果
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摘要
目的比较不同锌制剂治疗小儿抗生素相关性腹泻的临床效果。方法选取我院2015年9月～2017年9月收治的抗生素相关性腹泻患儿90例作为研究对象,按照随机数字表法分成参照组和观察组,各45例。参照组予葡萄糖酸锌治疗,观察组予锌硒制剂治疗,比较两组治疗效果和临床症状消失时间。结果观察组治疗总有效率高于参照组(95.56%vs 82.22%),且观察组发热、恶心呕吐、腹泻消失时间均短于参照组,差异具有统计学意义(P<0.05)。结论锌制剂对小儿抗生素相关性腹泻的临床治疗效果显著,其中锌硒制剂对小儿抗生素相关性腹泻的治疗效果优于葡萄糖酸锌制剂,能有效缩短患儿临床症状消失时间。
Objective To compare the clinical effects of different zinc preparations in the treatment of antibiotic-associated diarrhea in children.Methods A total of 90 children with antibiotic-associated diarrhea admitted to our hospital from September 2015 to September 2017 were enrolled in the study. According to the random number table method, they were divided into reference group and observation group, 45 cases each. The reference group was treated with zinc gluconate, and the observation group was treated with zinc selenium preparation. The treatment effect and the disappearance time of clinical symptoms were compared between the two groups. Results The total effective rate of the observation group was higher than that of the reference group(95.56% vs 82.22%). The fever, nausea and vomiting and diarrhea disappeared in the observation group were shorter than the reference group,the difference was statistically significant(P <0.05). Conclusion Zinc preparation has a significant clinical effect on antibiotic-associated diarrhea in children. Among them, zinc selenium preparation is better than zinc gluconate preparation in the treatment of antibiotic-associated diarrhea in children, which can effectively shorten the disappearance of clinical symptoms.
Objective To compare the clinical effects of different zinc preparations in the treatment of antibiotic-associated diarrhea in children.Methods A total of 90 children with antibiotic-associated diarrhea admitted to our hospital from September 2015 to September 2017 were enrolled in the study. According to the random number table method, they were divided into reference group and observation group, 45 cases each. The reference group was treated with zinc gluconate, and the observation group was treated with zinc selenium preparation. The treatment effect and the disappearance time of clinical symptoms were compared between the two groups. Results The total effective rate of the observation group was higher than that of the reference group(95.56% vs 82.22%). The fever, nausea and vomiting and diarrhea disappeared in the observation group were shorter than the reference group,the difference was statistically significant(P <0.05). Conclusion Zinc preparation has a significant clinical effect on antibiotic-associated diarrhea in children. Among them, zinc selenium preparation is better than zinc gluconate preparation in the treatment of antibiotic-associated diarrhea in children, which can effectively shorten the disappearance of clinical symptoms.
引文
[1]麻玮丽,王若楠.集束化护理干预在预防新生儿抗菌药物相关性腹泻中的应用价值[J].黑龙江医药科学,2018,41(3):190-191.
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[3]马静岩,杨丽萍.肠道微生物调节剂和锌制剂对54例小儿抗生素相关性腹泻的临床效果观察[J].贵州医药,2017,41(7):729-730.
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[6]姚海燕.抗生素相关性腹泻的临床特征分析[J].临床合理用药杂志,2017,10(24):49-51.
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[8]和艳菊.不同锌制剂治疗小儿抗生素相关性腹泻及预防腹泻的临床效果比较[J].医学信息,2016,29(2):135-136.
[2]姚晶晶.不同锌制剂治疗小儿抗生素相关性腹泻及预防腹泻的临床效果对比研究[J].中国社区医师,2018,34(17):74,76.
[3]马静岩,杨丽萍.肠道微生物调节剂和锌制剂对54例小儿抗生素相关性腹泻的临床效果观察[J].贵州医药,2017,41(7):729-730.
[4]林岩.不同锌制剂治疗小儿抗生素相关性腹泻及预防腹泻的临床效果比较[J].中外女性健康研究,2016(7):193,187.
[5]李金林.重症细菌性肺炎患儿抗生素相关性腹泻的相关因素及用药分析[J].儿科药学杂志,2017(3):49-51.
[6]姚海燕.抗生素相关性腹泻的临床特征分析[J].临床合理用药杂志,2017,10(24):49-51.
[7]曲华,李玢.不同锌制剂治疗小儿抗生素相关性腹泻及预防腹泻的临床效果比较[J].中国全科医学,2014,17(8):940-942.
[8]和艳菊.不同锌制剂治疗小儿抗生素相关性腹泻及预防腹泻的临床效果比较[J].医学信息,2016,29(2):135-136.