彩色多普勒超声在2型糖尿病合并亚临床甲减患者下肢动脉硬化诊断价值
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摘要
目的应用超声检测2型糖尿病合并亚临床甲减患者下肢动脉硬化,评价其诊断价值。方法选取患者90例,其中45例2型糖尿病合并亚临床甲减患者作为研究组,45例2型糖尿病患者作为对照组,对比两组间临床、生化指标、下肢动脉超声检查结果。结果研究组动脉内-中膜较对照组增厚,差异无统计学意义(P>0.05),与对照组比较,研究组TC、TG、LDL-C、TSH、TPOAb、TGAb水平升高,下肢动脉血管阻力指数、膝以下动脉斑块发生率、狭窄发生率、峰值流速均高于对照组,差异有统计学意义(P<0.05)。结论彩超可评估下肢动脉粥样硬化病变,协助临床干预治疗亚临床甲减患者,减缓动脉硬化进程。
Objective Ultrasound was used to detect arteriosclerosis of lower extremity in patients with type 2 diabetes mellitus complicated with subclinical hypothyroidism and evaluate its diagnostic value.Methods 90 patients were selected,45 patients with type 2 diabetes mellitus complicated with subclinical hypothyroidism as the study group,45 patients with type 2 diabetes mellitus as the control group,and the clinical,biochemical indicators,lower extremity arterial ultrasound results were compared between the two groups.Results The intima-media thickness in the study group was significantly thicker than that in the control group(P>0.05).Compared with the control group,the levels of TC,TG,LDL-C,TSH,TPOAb and TGAb in the study group were higher,and the lower extremity arterial resistance index,the incidence of subgenicular artery plaque,the incidence of stenosis and peak velocity were higher than those in the control group.There was statistical significance(P<0.05).Conclusions Color Doppler ultrasound can evaluate atherosclerotic lesions of lower extremities,assist clinical intervention in the treatment of subclinical hypothyroidism,and slow down the process of atherosclerosis.
Objective Ultrasound was used to detect arteriosclerosis of lower extremity in patients with type 2 diabetes mellitus complicated with subclinical hypothyroidism and evaluate its diagnostic value.Methods 90 patients were selected,45 patients with type 2 diabetes mellitus complicated with subclinical hypothyroidism as the study group,45 patients with type 2 diabetes mellitus as the control group,and the clinical,biochemical indicators,lower extremity arterial ultrasound results were compared between the two groups.Results The intima-media thickness in the study group was significantly thicker than that in the control group(P>0.05).Compared with the control group,the levels of TC,TG,LDL-C,TSH,TPOAb and TGAb in the study group were higher,and the lower extremity arterial resistance index,the incidence of subgenicular artery plaque,the incidence of stenosis and peak velocity were higher than those in the control group.There was statistical significance(P<0.05).Conclusions Color Doppler ultrasound can evaluate atherosclerotic lesions of lower extremities,assist clinical intervention in the treatment of subclinical hypothyroidism,and slow down the process of atherosclerosis.
引文
[1]邱萍.彩色多普勒超声在糖尿病患者下肢血管病变的诊断价值.实用医学影像杂志,2017,18(5):393-395.
[2] CENTENO M M,GOMEZ RASJIDO L,FREGENAL M,et al.Prevalence of thyroid dysfunction in patients with type2diabetes mellitus[J].Medicine(B Aires),2016,76(6):355-358.
[3]李辉,杨青青,裴晓燕.2型糖尿病合并甲状腺功能减退患者中红细胞分布宽度与颈动脉粥样硬化相关性研究[J].齐齐哈尔医学院学报,2016,37(23):2888-2890.
[4]中华医学会糖尿病学分会.中国2型糖尿病防治指南(2013年版)[J].中国糖尿病杂志,2015,88(3):26-89.
[5]唐杰,温朝阳,主编.腹部和外周血管彩色多普勒超声诊断学:第3版[M].北京:人民卫生出版社,2007:206-208.
[6]刘文静,吕焱.左旋甲状腺素片治疗对妊娠合并亚临床甲状腺功能减退孕妇妊娠结局的影响[J].中国妇幼保健,2016,31(17):3506-3508.
[7]景蓉,李秀琴.妊娠期甲状腺功能减退与妊娠期糖尿病对妊娠结局的影响及相关性分析[J].解放军医药杂志,2017,29(8):66-71.
[8]黄婧.亚临床甲状腺功能减退治疗进展[J].中国明康医学,2015,27(6):82-83.
[9]林蓉香,岳媛,张亚萍.亚临床甲状腺功能减退症与心血管疾病研究进展[J].实用心脑肺血管病杂志,2017,25(8):7-10.
[10] LOPEZ R M A,TARRAGA L PJ,RODRIGUEZ M J A,et al.Subclinical hypothyroidism and cardiovascular risk[J].Nutricion Hospital aria,2015,31(50):2095-2102.
[11]田利民,杨斌,高翠霞,等.亚临床甲状腺功能减退症患者TSH与动脉粥样硬化相关因子关系的研究[J].中华内分泌代谢杂志,2015,(2):133.
[12]郭郁郁,陈颖超,隋春华.2型糖尿病患者亚临床甲状腺功能减退症与颈动脉粥样硬化的相关性研究[J].实用临床医药杂志,2015,19(19):16-18.
[13]隋森,于扬,张弢,等.老年糖尿病合并亚临床甲减患者颅内动脉粥样硬化发生及影响因素分析[J].疑难病杂志,2017,16(9):877-880.
[14]陈丹.彩色多普勒超声真的糖尿病下肢血管病变研究[J].糖尿病新世界,2017,23:166-167.
[2] CENTENO M M,GOMEZ RASJIDO L,FREGENAL M,et al.Prevalence of thyroid dysfunction in patients with type2diabetes mellitus[J].Medicine(B Aires),2016,76(6):355-358.
[3]李辉,杨青青,裴晓燕.2型糖尿病合并甲状腺功能减退患者中红细胞分布宽度与颈动脉粥样硬化相关性研究[J].齐齐哈尔医学院学报,2016,37(23):2888-2890.
[4]中华医学会糖尿病学分会.中国2型糖尿病防治指南(2013年版)[J].中国糖尿病杂志,2015,88(3):26-89.
[5]唐杰,温朝阳,主编.腹部和外周血管彩色多普勒超声诊断学:第3版[M].北京:人民卫生出版社,2007:206-208.
[6]刘文静,吕焱.左旋甲状腺素片治疗对妊娠合并亚临床甲状腺功能减退孕妇妊娠结局的影响[J].中国妇幼保健,2016,31(17):3506-3508.
[7]景蓉,李秀琴.妊娠期甲状腺功能减退与妊娠期糖尿病对妊娠结局的影响及相关性分析[J].解放军医药杂志,2017,29(8):66-71.
[8]黄婧.亚临床甲状腺功能减退治疗进展[J].中国明康医学,2015,27(6):82-83.
[9]林蓉香,岳媛,张亚萍.亚临床甲状腺功能减退症与心血管疾病研究进展[J].实用心脑肺血管病杂志,2017,25(8):7-10.
[10] LOPEZ R M A,TARRAGA L PJ,RODRIGUEZ M J A,et al.Subclinical hypothyroidism and cardiovascular risk[J].Nutricion Hospital aria,2015,31(50):2095-2102.
[11]田利民,杨斌,高翠霞,等.亚临床甲状腺功能减退症患者TSH与动脉粥样硬化相关因子关系的研究[J].中华内分泌代谢杂志,2015,(2):133.
[12]郭郁郁,陈颖超,隋春华.2型糖尿病患者亚临床甲状腺功能减退症与颈动脉粥样硬化的相关性研究[J].实用临床医药杂志,2015,19(19):16-18.
[13]隋森,于扬,张弢,等.老年糖尿病合并亚临床甲减患者颅内动脉粥样硬化发生及影响因素分析[J].疑难病杂志,2017,16(9):877-880.
[14]陈丹.彩色多普勒超声真的糖尿病下肢血管病变研究[J].糖尿病新世界,2017,23:166-167.