脓毒症患者早期急性胃肠功能损伤2种分级标准评估的临床研究
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摘要
目的:比较脓毒症患者早期急性胃肠功能损伤GIF和AGI评分标准评估的临床应用差异性。方法:在入选患者入老年重症医学科时给予肠道功能评分量表(GIF和AGI评分标准)评分。结果:在脓毒症伴随急性胃肠功能损伤患者中AGI标准诊断率高于GIF标准诊断率(P=0.022),差异有统计学意义。GIF、AGI标准预测患者院内死亡的ROC曲线AUC分别为0.614和0.734。结论:在急性胃肠功能损伤患者中可使用AGI标准进行病情评估,在预测患者院内死亡方面,AGI标准比GIF标准更为准确。
Objective: To compare the clinical application of GIF and AGI in patients with early acute gastrointestinal injury. Methods: The intestinal function score scale(GIF and AGI) was given to the selected patients when they were admitted to geriatric critical medicine department. Results: The diagnostic rate of AGI standard was higher than that of GIF standard in sepsis patients with acute gastrointestinal dysfunction(P =0.022), and the difference was statistically significant. The ROC curve AUC of GIF and AGI for predicting hospital mortality was 0.614 and 0.734, respectively. Conclusion: AGI criteria can be used to assess the condition of patients with acute gastrointestinal dysfunction. AGI standard is more accurate than GIF standard in predicting the probability of patients to die in hospital.
Objective: To compare the clinical application of GIF and AGI in patients with early acute gastrointestinal injury. Methods: The intestinal function score scale(GIF and AGI) was given to the selected patients when they were admitted to geriatric critical medicine department. Results: The diagnostic rate of AGI standard was higher than that of GIF standard in sepsis patients with acute gastrointestinal dysfunction(P =0.022), and the difference was statistically significant. The ROC curve AUC of GIF and AGI for predicting hospital mortality was 0.614 and 0.734, respectively. Conclusion: AGI criteria can be used to assess the condition of patients with acute gastrointestinal dysfunction. AGI standard is more accurate than GIF standard in predicting the probability of patients to die in hospital.
引文
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[4] HERNáNDEZ-PALAZóN J, FUENTES-GARCíA D,BURGUILLOS-LóPEZ S, et al. Analysis of organ failure and mortality in sepsis due to secondary peritonitis[J]. Med Intensiva, 2013, 37(7):461-467.
[5]但汉雷,张亚历,张振书,等.小肠功能障碍与衰竭的诊断和评分[J].世界华人消化杂志, 2002, 10(10):1170-1176.
[6] SHI L, HU L H. The normal flora may contribute to the quantitative preponderance of myeloid cells under physiological conditions[J]. Med Hypotheses, 2011, 76(1):141-143.
[7]何振扬. 2017 ESICM重症患者早期肠内营养指南解读[J].中华重症医学电子杂志(网络版), 2018, 4(1):51-56.
[8]许媛.急性胃肠黏膜损伤:病理生理与治疗[J].中华重症医学电子杂志, 2016, 2(1):16-20.
[2] TIAN R, TAN J T, WANG R L, et al. The role of intestinal mucosa oxidative stress in gut barrier dysfunction of severe acute pancreatitis[J]. Eur Rev Med Pharmacol Sci, 2013, 17(3):349-355.
[3] AN G, NAMAS R A, VODOVOTZ Y. Sepsis:from pattern to mechanism and back[J]. Crit Rev Biomed Eng, 2012, 40(4):341-351.
[4] HERNáNDEZ-PALAZóN J, FUENTES-GARCíA D,BURGUILLOS-LóPEZ S, et al. Analysis of organ failure and mortality in sepsis due to secondary peritonitis[J]. Med Intensiva, 2013, 37(7):461-467.
[5]但汉雷,张亚历,张振书,等.小肠功能障碍与衰竭的诊断和评分[J].世界华人消化杂志, 2002, 10(10):1170-1176.
[6] SHI L, HU L H. The normal flora may contribute to the quantitative preponderance of myeloid cells under physiological conditions[J]. Med Hypotheses, 2011, 76(1):141-143.
[7]何振扬. 2017 ESICM重症患者早期肠内营养指南解读[J].中华重症医学电子杂志(网络版), 2018, 4(1):51-56.
[8]许媛.急性胃肠黏膜损伤:病理生理与治疗[J].中华重症医学电子杂志, 2016, 2(1):16-20.