贵阳市机关职工体检人群血脂异常患病率现况调查
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摘要
目的:调查贵阳市机关职工体检人群血脂异常患病率现况。方法:收集2013年贵阳市机关职工体检资料,包括性别、年龄、血清甘油三酯(TG)、血清总胆固醇(TC)、高密度脂蛋白胆固醇(HDL-C)水平,分析不同性别各年龄组体检者高TG血症、高TC血症及低HDL-C血症异常患病率分布。结果:体检者共62 359例,男性33 886例(54.34%),女性28 453例(45.66%),总的血脂异常患病率为64.86%,血脂异常患病率随受试者年龄的增长呈上升趋势(P<0.05),男性高于女性(P<0.05);<50岁的各年龄组男性血脂异常患病率高于女性(P<0.05),≥55~<85岁的各年龄组男性血脂异常患病率低于女性(P<0.05);体检者总高TG、高TC血症及低HDL-C血症异常患病率分别为34.18%、31.22%、23.21%,差异有统计学意义(P<0.05);其中,高TG血症异常率比较,<60岁各年龄组男性高于女性,≥60~<85岁的各年龄组男性低于女性(P<0.05);高TC血症异常率比较,<50岁各年龄组男性高于女性,≥50岁的各年龄组男性低于女性(P<0.05);低HDL-C血症异常率在所有年龄组男性低于女性(P<0.05)。结论:贵阳市机关职工总体高TG血症、高TC血症及低HDL-C血症异常患病率较高。
Objective: To investigate the prevalence of dyslipidemia in physical check population of government staff in Guiyang. Methods: Collecting following data from 2013 government staff physical check: gender,age,TG,TC,HDL-C level,analyzing abnormal prevalence distribution of high TG disease,high TC disease and low HDL-C disease according to gender and age differences. Result: Of the total 62 359 physical check participants,there were 33 886 males( 54. 34%),28 453 females( 45. 66%),total dyslipidemia prevalence was 64. 86%; dyslipidemia prevalence rate increased with the increasement of age of patients( P < 0. 05),that of males were higher than that of females( P <0. 05); comparison among age groups under 50,morbidity of male was higher than that of female( P <0. 05); while in age groups from≥55 to < 85,morbidity of males was lower than that of female( P <0. 05). Total dyslipidemia morbidity of participants were 34. 18%,31. 22% and 23. 21% respectively,differences were statistical significant( P < 0. 05). According to the results,high TG disease abnormal ratio showed that,age groups below 60 showed males were higher than that of female,age groups over 60 showed males were lower than females( P < 0. 05).Comparison of high TC disease abnormal ratio showed that,age groups below 50,males were higher than females,age groups over 55,males were higher than female; low HDL-C disease abnormal ratio in all age groups showed lower ratio in male than female( overall P < 0. 05). Conclusion: The prevalence of dyslipidemia of government staff in Guiyang was higher than that of national level.
Objective: To investigate the prevalence of dyslipidemia in physical check population of government staff in Guiyang. Methods: Collecting following data from 2013 government staff physical check: gender,age,TG,TC,HDL-C level,analyzing abnormal prevalence distribution of high TG disease,high TC disease and low HDL-C disease according to gender and age differences. Result: Of the total 62 359 physical check participants,there were 33 886 males( 54. 34%),28 453 females( 45. 66%),total dyslipidemia prevalence was 64. 86%; dyslipidemia prevalence rate increased with the increasement of age of patients( P < 0. 05),that of males were higher than that of females( P <0. 05); comparison among age groups under 50,morbidity of male was higher than that of female( P <0. 05); while in age groups from≥55 to < 85,morbidity of males was lower than that of female( P <0. 05). Total dyslipidemia morbidity of participants were 34. 18%,31. 22% and 23. 21% respectively,differences were statistical significant( P < 0. 05). According to the results,high TG disease abnormal ratio showed that,age groups below 60 showed males were higher than that of female,age groups over 60 showed males were lower than females( P < 0. 05).Comparison of high TC disease abnormal ratio showed that,age groups below 50,males were higher than females,age groups over 55,males were higher than female; low HDL-C disease abnormal ratio in all age groups showed lower ratio in male than female( overall P < 0. 05). Conclusion: The prevalence of dyslipidemia of government staff in Guiyang was higher than that of national level.
引文
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[3]JELLINGER P S,HANDELSMAN Y,ROSENBLIT P D,et al.American association of clinical endocrinologists and american college of endocrinology guidelines for management of dyslipidemia and prevention of cardiovascular disease[J].Endocrine Practice:Official Journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists,2017,23(s2):1-87.
[4]诸骏仁,高润霖,赵水平.中国成人血脂异常防治指南(2016年修订版)[J].中国循环杂志,2016,31(10):937-953.
[5]HALCOX J P,BANEGAS J R,ROY C,et al.Prevalence and treatment of atherogenic dyslipidemia in the primary prevention of cardiovascular disease in Europe:EURIKA,a cross-sectional observational study[J].BMC Cardiovasc Disord,2017,17(1):160.
[6]COHEN A M,RADER D J.Dyslipidemia[J].Current Treatment Options in Cardiovascular Medicine,2001,3(4):347-357.
[7]DEEPIKA P,RAJESHWARY A,USHA S,et al.Does dyslipidemia worsen the hearing level in diabetics[J].Journal of Otology,2017,12(4):198-201.
[8]中国成人血脂异常防治指南[J].中华心血管病杂志,2007,(5):390-419.
[9]李立明,饶克勤,孔灵芝.中国居民2002年营养与健康状况调查[J].中华流行病学杂志,2005,(7):478-484.
[10]国家卫生和计划生育委员会疾病预防控制报告(2015).中国居民营养与慢性病状况报告[C].人民卫生出版社,2015.
[11]张坚,满青青,王春荣.中国18岁及以上人群血脂水平及分布特征[J].中华预防医学杂志,2005,(5):8-11.
[12]段丹,杨大刚,李俊良.贵阳市13 444例成年体检人群代谢综合征流行现状分析[J].贵州医科大学学报,2017,42(4):449-453.
[13]杨雪莹,王亭,王亚平.天津市成年居民血脂异常流行特征及影响因素分析[J].中国公共卫生,2016,38(3):286-290.
[14]QI L,DING X,TANG W,et al.Prevalence and risk factors associated with dyslipidemia in chongqing,china[J].Int J Environ Res Public Health,2015,12(10):13455-13465.
[15]杨丽梅,赵艳华,路海英.北京市怀柔区居民血脂异常分布特征及影响因素[J].现代预防医学,2015,40(8):1436-1440.
[16]GE P,DONG C,REN X,et al.The high prevalence of low HDL-Cholesterol levels and dyslipidemia in rural populations in northwestern china[J].Plos One,2015,10(12):e0144104.
[17]SUN G Z,LI Z,GUO L,et al.High prevalence of dyslipidemia and associated risk factors among rural Chinese adults[J].Lipids in Health and Disease,2014,13(1):189.
[18]LUO J Y,MA Y T,YU Z X,et al.Prevalence,awareness,treatment and control of dyslipidemia among adults in Northwestern China:the cardiovascular risk survey[J].Lipids in Health and Disease,2014,13(1):4.
[19]DOUPA D,SECK S M,DIA C A,et al.Dyslipidemia,obesity and other cardiovascular risk factors in the adult population in Senegal[J].The Pan African medical journal,2014,19:181.
[20]SHARMA U,KISHORE J,GARG A,et al.Dyslipidemia and associated risk factors in a resettlement colony of Delhi[J].J Clin Lipidol,2013,7(6):653-660.