巴戟天微型饮片工艺优选
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摘要
目的优选巴戟天微型饮片切制工艺参数,探讨其是否适用于不同产地来源的巴戟天。方法以蒸制时间、饮片长度、饮片厚度、烘干温度为影响因素,以水晶兰苷、去乙酰车叶草苷酸、甲基异茜草素-1-甲醚、甲基异茜草素、耐斯糖的含量及出膏率、休止角为评价指标,采用正交试验优选巴戟天微型饮片切制工艺,并建立不同产地来源巴戟天微型饮片HPLC指纹图谱。结果巴戟天微型饮片最佳切制工艺为:常压蒸制软化30 min,切片长度3 mm,切片宽度1～2 mm,40℃烘干。结论巴戟天微型饮片软化切制工艺简单易行,具有良好的适用性。
Objective To optimize cutting process for Morindae Officinalis Radix miniature decoction pieces; To investigate whether the cutting technology was suitable for Morindae Officinalis Radix from different producing areas. Methods Steaming time, length of decoction pieces, thickness of decoction pieces, and drying temperature were set as influencing factors, and the contents of crystal lanolin, deacetyl levulinic acid, methyl isophorin-1-methyl ether, methyl isophorin, nes sugar, and the rate of ointment and angle of repose were set as evaluation indexes. The orthogonal test was used to optimize the cutting process of Morindae Officinalis Radix miniature decoction pieces, and HPLC fingerprints of Morindae Officinalis Radix miniature decoction pieces from different producing areas were established. Results The optimal cutting process for Morindae Officinalis Radix miniature decoction pieces was steaming 30 min, then cutting into 3 mm length and 1–2 mm width, and the drying temperature was 40 ℃. Conclusion The optimal cutting process for Morindae Officinalis Radix miniature decoction pieces is easy to conduct, with good applicability.
Objective To optimize cutting process for Morindae Officinalis Radix miniature decoction pieces; To investigate whether the cutting technology was suitable for Morindae Officinalis Radix from different producing areas. Methods Steaming time, length of decoction pieces, thickness of decoction pieces, and drying temperature were set as influencing factors, and the contents of crystal lanolin, deacetyl levulinic acid, methyl isophorin-1-methyl ether, methyl isophorin, nes sugar, and the rate of ointment and angle of repose were set as evaluation indexes. The orthogonal test was used to optimize the cutting process of Morindae Officinalis Radix miniature decoction pieces, and HPLC fingerprints of Morindae Officinalis Radix miniature decoction pieces from different producing areas were established. Results The optimal cutting process for Morindae Officinalis Radix miniature decoction pieces was steaming 30 min, then cutting into 3 mm length and 1–2 mm width, and the drying temperature was 40 ℃. Conclusion The optimal cutting process for Morindae Officinalis Radix miniature decoction pieces is easy to conduct, with good applicability.
引文
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[12]谢伟杰,张永萍,徐剑,等.精源胶囊辅料筛选与成型工艺研究[J].亚太传统医药,2015,11((15):33-35.
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[2]陈士林,黄志海,丘小惠,等.中药精准煮散饮片[J].世界科学技术-中医药现代化,2016,118(9):1430-14440.
[3]成金乐,赖智填,彭丽华.中药破壁饮饮片研究[J].世界科学技术-中医药现代化,2014,16(2):254-262.
[4]余香香,龚千锋,朱龙涛,等.中药传统饮片片型的研究现状与发展[J].江西中医学院学报,2011,223(1):88-90.
[5]国家药典委员会.中华人民共和国药典:一部[M].北京:中国医药科技出版社,2015:81.
[6]陈美燕.巴戟天化学成分研究进展[J].云南中医中药杂志,2009,30(111):63.
[7]胡疆,张卫东,柳润辉,等.巴戟天化学成分及其生理活性研究进展[J].药学实践杂志,2004,222(4):196-199,219.
[8]崔承彬,杨明,姚志伟,等.中药巴戟天中抗抑郁活性成分的研究[J].中国中药杂志,1995,20((l):36.
[9]徐敏,邓响潮,张晓晖,等.巴戟滋补膏对甲状腺切除后致阳虚兔血清甲状腺激素等水平的影响[J].华西医科大学学报,1994,,25(4):431.
[10]黄玉秋,贾天柱,史辑.正交试验优选巴戟天饮片的软化和切制工艺[J].中国实验方剂学杂志,2015,21(16):5-9.
[11]史辑,崔妮,景海漪,等.炮制对巴戟天中茜草素型蒽醌类成分的影响[J].中成药,2015,37(6):1289-1292.
[12]谢伟杰,张永萍,徐剑,等.精源胶囊辅料筛选与成型工艺研究[J].亚太传统医药,2015,11((15):33-35.
[13]张成俊,周澜.浅述中药饮片的传统切制经验及其规格[J].时珍国医国药,,2007,18(8):19960-1961.
[14]陈伟英.中药饮片机械化包装研究[J].实用中医药杂志,2007,23(11):742-7743.