经阴道三维超声测定子宫内膜容积对异位妊娠的预测价值
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摘要
目的:探讨经阴道三维超声测定子宫内膜容积对异位妊娠的预测价值。方法:应用经阴道三维超声对120例疑似异位妊娠患者,进行子宫内膜容积的检测。根据子宫内膜容积将患者分为三组(<2 ml、2~4 ml、>4 ml),比较各组的妊娠结局。根据正常妊娠与异位妊娠分为两组,比较两组的子宫内膜容积。结果:120例患者中,临床妊娠97例。子宫内膜容积<2 ml组、2~4 ml组、>4 ml组的妊娠结局比较,差异均无统计学意义(P>0.05)。正常妊娠组和异位妊娠组子宫内膜容积比较,差异无统计学意义(ROC曲线下面积=0.539)。子宫内膜容积与异位妊娠有相关性,但非完全线性相关(rs=0.724 8)。结论:子宫内膜容积不能完全预测异位妊娠,但对于临床判断是否为异位妊娠具有一定的指导意义。
Objective:To investigate the predictive value of transvaginal three-dimensional ultrasound in the determination of endometrial volume in ectopic pregnancy.Method:The volume of endometrium was measured in 120 patients with suspected ectopic pregnancy by transvaginal three-dimensional ultrasound.According to endometrial volume,the patients were divided into three groups(<2 ml,2-4 ml,>4 ml),and the pregnancy outcomes were compared.According to normal pregnancy and ectopic pregnancy,the patients were divided into two groups,and endometrial volume were compared.Result:There were 97 cases of clinical pregnancy among the 120 patients.Compared the pregnancy outcomes between the endometrial volume <2 ml group,2~4 ml group and >4 ml group,there was no significant difference(P>0.05).There was no significant difference in endometrial volume between normal pregnancy and ectopic pregnancy(areas under the ROC curve=0.539).Endometrial volume was associated with ectopic pregnancy,but not entirely linear(rs=0.724 8).Conclusion:The volume of endometrium can not predict the ectopic pregnancy,but it has some guiding significance for the clinical diagnosis of ectopic pregnancy
Objective:To investigate the predictive value of transvaginal three-dimensional ultrasound in the determination of endometrial volume in ectopic pregnancy.Method:The volume of endometrium was measured in 120 patients with suspected ectopic pregnancy by transvaginal three-dimensional ultrasound.According to endometrial volume,the patients were divided into three groups(<2 ml,2-4 ml,>4 ml),and the pregnancy outcomes were compared.According to normal pregnancy and ectopic pregnancy,the patients were divided into two groups,and endometrial volume were compared.Result:There were 97 cases of clinical pregnancy among the 120 patients.Compared the pregnancy outcomes between the endometrial volume <2 ml group,2~4 ml group and >4 ml group,there was no significant difference(P>0.05).There was no significant difference in endometrial volume between normal pregnancy and ectopic pregnancy(areas under the ROC curve=0.539).Endometrial volume was associated with ectopic pregnancy,but not entirely linear(rs=0.724 8).Conclusion:The volume of endometrium can not predict the ectopic pregnancy,but it has some guiding significance for the clinical diagnosis of ectopic pregnancy
引文
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[13]俞慧,陈萍.经阴道超声诊断早期异位妊娠的临床价值[J].临床和实验医学杂志,2013,12(6):447.
[2]Ng E H,Yeung W S,Ho P C.Endometrial and subendometrial vascularity are significantly lower in patients with endometrial volume 2.5 ml or less[J].Reprod Biomed Online,2009,18(2):262-268.
[3]Horcajadas J A,Pellicer A,Simón C.Wide genomic analysis of human endometrial receptivity:new times,new opportunities[J].Hum Reprod Update,2007,13(1):77-86.
[4]乐杰.妇产科学[M].第7版.北京:人民卫生出版社,2008:105.
[5]曹泽毅.中华妇产科学(临床版)[M].北京:人民卫生出版社,2010:315-317.
[6]魏璐华,黎莉,戴峻,等.血清β-h CG、Prog检测联合阴道彩超对异位妊娠早期诊断的临床应用价值[J].现代诊断与治疗,2013,24(4):750-751.
[7]李慧东.超声在辅助生殖助孕技术中的应用[J].国外医学能计划生育/生殖健康分册,2007,26(1):17-20.
[8]Komine A S,Majima H,Yoshida N C,et a1.Stimuli through toll like receptor(TLR)3 and 9 affect human chorionic gonadtropin(h CG)production in a choriocarcinom a cell line[J].Obstet Gynaecol Res,2008,34(2):144.
[9]周永昌,郭万学.超声医学[M].第4版.北京:北京科学技术出版社,2003:1394.
[10]Isaacs J J,Wells C S,Williams D B,et a1.Endometrial thickness is a valid monitoring parameter in cycles of ovulation induction with menotropins alone[J].Fertil Steril,1996,65(2):262-266.
[11]Yang J H,Wu M Y,Chen C D,et a1.Association of endometrial blood flow as determined by amodified color doppler technique with subsequent outcome of invitro fertilization[J].Hum Reprod,1999,14(6):1606-1610.
[12]王艳,冯丽华,张萌,等.阴道超声下子宫内膜厚度与血清β-h CG联合检测异位妊娠早期的诊断价值[J].中国妇幼保健,2013,28(15):2415-2417.
[13]俞慧,陈萍.经阴道超声诊断早期异位妊娠的临床价值[J].临床和实验医学杂志,2013,12(6):447.